6IZ4

Crystal Structure Analysis of TRIC counter-ion channels in calcium release

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005267	molecular_function	potassium channel activity
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006811	biological_process	monoatomic ion transport
A	0006813	biological_process	potassium ion transport
A	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
A	0071805	biological_process	potassium ion transmembrane transport
B	0005267	molecular_function	potassium channel activity
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006811	biological_process	monoatomic ion transport
B	0006813	biological_process	potassium ion transport
B	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
B	0071805	biological_process	potassium ion transmembrane transport
C	0005267	molecular_function	potassium channel activity
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0006811	biological_process	monoatomic ion transport
C	0006813	biological_process	potassium ion transport
C	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
C	0071805	biological_process	potassium ion transmembrane transport
D	0005267	molecular_function	potassium channel activity
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0006811	biological_process	monoatomic ion transport
D	0006813	biological_process	potassium ion transport
D	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
D	0071805	biological_process	potassium ion transmembrane transport
E	0005267	molecular_function	potassium channel activity
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0006811	biological_process	monoatomic ion transport
E	0006813	biological_process	potassium ion transport
E	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
E	0071805	biological_process	potassium ion transmembrane transport
F	0005267	molecular_function	potassium channel activity
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0006811	biological_process	monoatomic ion transport
F	0006813	biological_process	potassium ion transport
F	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
F	0071805	biological_process	potassium ion transmembrane transport
G	0005267	molecular_function	potassium channel activity
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0006811	biological_process	monoatomic ion transport
G	0006813	biological_process	potassium ion transport
G	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
G	0071805	biological_process	potassium ion transmembrane transport
H	0005267	molecular_function	potassium channel activity
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0006811	biological_process	monoatomic ion transport
H	0006813	biological_process	potassium ion transport
H	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042802	molecular_function	identical protein binding
H	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
H	0071805	biological_process	potassium ion transmembrane transport
I	0005267	molecular_function	potassium channel activity
I	0005783	cellular_component	endoplasmic reticulum
I	0005789	cellular_component	endoplasmic reticulum membrane
I	0006811	biological_process	monoatomic ion transport
I	0006813	biological_process	potassium ion transport
I	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0042802	molecular_function	identical protein binding
I	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
I	0071805	biological_process	potassium ion transmembrane transport
J	0005267	molecular_function	potassium channel activity
J	0005783	cellular_component	endoplasmic reticulum
J	0005789	cellular_component	endoplasmic reticulum membrane
J	0006811	biological_process	monoatomic ion transport
J	0006813	biological_process	potassium ion transport
J	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0042802	molecular_function	identical protein binding
J	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
J	0071805	biological_process	potassium ion transmembrane transport
K	0005267	molecular_function	potassium channel activity
K	0005783	cellular_component	endoplasmic reticulum
K	0005789	cellular_component	endoplasmic reticulum membrane
K	0006811	biological_process	monoatomic ion transport
K	0006813	biological_process	potassium ion transport
K	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
K	0016020	cellular_component	membrane
K	0034220	biological_process	monoatomic ion transmembrane transport
K	0042802	molecular_function	identical protein binding
K	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
K	0071805	biological_process	potassium ion transmembrane transport
L	0005267	molecular_function	potassium channel activity
L	0005783	cellular_component	endoplasmic reticulum
L	0005789	cellular_component	endoplasmic reticulum membrane
L	0006811	biological_process	monoatomic ion transport
L	0006813	biological_process	potassium ion transport
L	0014808	biological_process	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
L	0016020	cellular_component	membrane
L	0034220	biological_process	monoatomic ion transmembrane transport
L	0042802	molecular_function	identical protein binding
L	0051279	biological_process	regulation of release of sequestered calcium ion into cytosol
L	0071805	biological_process	potassium ion transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Transmembrane: {"description":"Helical;Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	396
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	276
Details	Transmembrane: {"description":"Helical;Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	408
Details	Topological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	228
Details	Transmembrane: {"description":"Helical;Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	216
Details	Transmembrane: {"description":"Helical;Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	204
Details	Transmembrane: {"description":"Helical;Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	204
Details	Transmembrane: {"description":"Helical;Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	240
Details	Transmembrane: {"description":"Helical;Name=7","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9NA73","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---