6IZ3
Structural basis for activity of TRIC counter-ion channels in calcium release
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
| C | 0005267 | molecular_function | potassium channel activity |
| C | 0005783 | cellular_component | endoplasmic reticulum |
| C | 0005789 | cellular_component | endoplasmic reticulum membrane |
| C | 0016020 | cellular_component | membrane |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| C | 0071805 | biological_process | potassium ion transmembrane transport |
| D | 0005267 | molecular_function | potassium channel activity |
| D | 0005783 | cellular_component | endoplasmic reticulum |
| D | 0005789 | cellular_component | endoplasmic reticulum membrane |
| D | 0016020 | cellular_component | membrane |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| D | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 192 |
| Details | TOPO_DOM: Lumenal => ECO:0000305 |
| Chain | Residue | Details |
| A | MET1-SER15 | |
| C | ALA69-THR79 | |
| C | THR122-ALA139 | |
| C | GLY197-ARG204 | |
| D | MET1-SER15 | |
| D | ALA69-THR79 | |
| D | THR122-ALA139 | |
| D | GLY197-ARG204 | |
| A | ALA69-THR79 | |
| A | THR122-ALA139 | |
| A | GLY197-ARG204 | |
| B | MET1-SER15 | |
| B | ALA69-THR79 | |
| B | THR122-ALA139 | |
| B | GLY197-ARG204 | |
| C | MET1-SER15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 64 |
| Details | TRANSMEM: Helical;Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET16-ALA32 | |
| B | MET16-ALA32 | |
| C | MET16-ALA32 | |
| D | MET16-ALA32 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 364 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | ARG33-HIS44 | |
| C | PHE100-ASN102 | |
| C | SER158-MET178 | |
| C | HIS226-LYS284 | |
| D | ARG33-HIS44 | |
| D | PHE100-ASN102 | |
| D | SER158-MET178 | |
| D | HIS226-LYS284 | |
| A | PHE100-ASN102 | |
| A | SER158-MET178 | |
| A | HIS226-LYS284 | |
| B | ARG33-HIS44 | |
| B | PHE100-ASN102 | |
| B | SER158-MET178 | |
| B | HIS226-LYS284 | |
| C | ARG33-HIS44 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 92 |
| Details | TRANSMEM: Helical;Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER45-LEU68 | |
| B | SER45-LEU68 | |
| C | SER45-LEU68 | |
| D | SER45-LEU68 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 76 |
| Details | TRANSMEM: Helical;Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | THR80-LEU99 | |
| B | THR80-LEU99 | |
| C | THR80-LEU99 | |
| D | THR80-LEU99 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 72 |
| Details | TRANSMEM: Helical;Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | CYS103-ARG121 | |
| B | CYS103-ARG121 | |
| C | CYS103-ARG121 | |
| D | CYS103-ARG121 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 68 |
| Details | TRANSMEM: Helical;Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP140-ILE157 | |
| B | TRP140-ILE157 | |
| C | TRP140-ILE157 | |
| D | TRP140-ILE157 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 68 |
| Details | TRANSMEM: Helical;Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER179-HIS196 | |
| B | SER179-HIS196 | |
| C | SER179-HIS196 | |
| D | SER179-HIS196 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical;Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS205-THR225 | |
| B | HIS205-THR225 | |
| C | HIS205-THR225 | |
| D | HIS205-THR225 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9NA73 |
| Chain | Residue | Details |
| A | LYS117 | |
| A | ARG121 | |
| B | LYS117 | |
| B | ARG121 | |
| C | LYS117 | |
| C | ARG121 | |
| D | LYS117 | |
| D | ARG121 |
