6IYY
Crystal structure of human WIPI3,loop deletion mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000045 | biological_process | autophagosome assembly |
| A | 0000407 | cellular_component | phagophore assembly site |
| A | 0000422 | biological_process | autophagy of mitochondrion |
| A | 0000425 | biological_process | pexophagy |
| A | 0005515 | molecular_function | protein binding |
| A | 0005764 | cellular_component | lysosome |
| A | 0005829 | cellular_component | cytosol |
| A | 0006914 | biological_process | autophagy |
| A | 0008289 | molecular_function | lipid binding |
| A | 0009267 | biological_process | cellular response to starvation |
| A | 0030674 | molecular_function | protein-macromolecule adaptor activity |
| A | 0032266 | molecular_function | phosphatidylinositol-3-phosphate binding |
| A | 0034045 | cellular_component | phagophore assembly site membrane |
| A | 0034497 | biological_process | protein localization to phagophore assembly site |
| A | 0044804 | biological_process | nucleophagy |
| A | 0061723 | biological_process | glycophagy |
| A | 0062078 | molecular_function | TSC1-TSC2 complex binding |
| A | 0080025 | molecular_function | phosphatidylinositol-3,5-bisphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ASN16 |
| A | LEU57 |
| A | PHE58 |
| A | ARG59 |
| A | HOH521 |
| A | HOH552 |
| A | HOH556 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ASN141 |
| A | SER142 |
| A | SER142 |
| A | HOH502 |
| A | HOH586 |
| A | HOH586 |
| A | ARG59 |
| A | ASN141 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | HIS175 |
| A | GLU176 |
| A | GLY177 |
| A | SER195 |
| A | LYS197 |
| A | ARG202 |
| A | HOH550 |
| A | HOH553 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | LYS197 |
| A | THR199 |
| A | ARG216 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG216 |
| A | LYS256 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ARG217 |
| A | THR244 |
| A | HIS246 |
| A | LYS261 |
| A | SO4407 |
| A | HOH532 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | LYS70 |
| A | ARG217 |
| A | GLY218 |
| A | SER219 |
| A | GLN220 |
| A | SO4406 |
| A | HOH532 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 39 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Motif: {"description":"L/FRRG motif","evidences":[{"source":"UniProtKB","id":"Q9Y4P8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
