Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
B | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | binding site for residue AWO A 1001 |
Chain | Residue |
A | LEU595 |
A | TYR672 |
A | CYS673 |
A | GLY676 |
A | LEU783 |
A | LEU799 |
A | CYS809 |
A | ASP810 |
A | PHE811 |
A | HOH1157 |
B | ASP760 |
A | ALA621 |
A | LYS623 |
A | GLU640 |
A | LEU644 |
A | LEU647 |
A | ILE653 |
A | THR670 |
A | GLU671 |
site_id | AC2 |
Number of Residues | 17 |
Details | binding site for residue AWO B 1001 |
Chain | Residue |
A | ASP760 |
B | LEU595 |
B | LYS623 |
B | GLU640 |
B | LEU644 |
B | LEU647 |
B | ILE653 |
B | THR670 |
B | GLU671 |
B | TYR672 |
B | CYS673 |
B | GLY676 |
B | LEU783 |
B | LEU799 |
B | CYS809 |
B | ASP810 |
B | PHE811 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 29 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGAGAFGKVVeAtaygliksdaamt.....VAVK |
Chain | Residue | Details |
A | LEU595-LYS623 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNILL |
Chain | Residue | Details |
A | CYS788-LEU800 | |
site_id | PS00240 |
Number of Residues | 14 |
Details | RECEPTOR_TYR_KIN_III Receptor tyrosine kinase class III signature. GnHmNIVNLLGACT |
Chain | Residue | Details |
A | GLY648-THR661 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP792 | |
B | ASP792 | |
site_id | SWS_FT_FI2 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
A | TYR568 | |
B | LYS623 | |
B | GLU671 | |
B | ARG796 | |
B | ASN797 | |
B | ASP810 | |
A | GLY596 | |
A | LYS623 | |
A | GLU671 | |
A | ARG796 | |
A | ASN797 | |
A | ASP810 | |
B | TYR568 | |
B | GLY596 | |
Chain | Residue | Details |
A | TYR547 | |
A | TYR553 | |
B | TYR547 | |
B | TYR553 | |
Chain | Residue | Details |
A | TYR568 | |
B | TYR568 | |
Chain | Residue | Details |
A | TYR570 | |
B | TYR570 | |
Chain | Residue | Details |
A | SER821 | |
B | SER821 | |
Chain | Residue | Details |
A | TYR823 | |
B | TYR823 | |
Chain | Residue | Details |
A | SER891 | |
B | SER891 | |
Chain | Residue | Details |
A | TYR900 | |
B | TYR900 | |