6IJN
The D295N mutant of the N6-methyl-AMP deaminase from Arabidopsis thaliana complexed with N6m-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004000 | molecular_function | adenosine deaminase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006154 | biological_process | adenosine catabolic process |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0009507 | cellular_component | chloroplast |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019239 | molecular_function | deaminase activity |
| A | 0046103 | biological_process | inosine biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0062154 | molecular_function | N6-methyl-AMP deaminase activity |
| A | 0110052 | biological_process | toxic metabolite repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue 6MZ A 401 |
| Chain | Residue |
| A | HIS15 |
| A | ASP160 |
| A | GLY190 |
| A | HIS217 |
| A | GLU220 |
| A | HIS240 |
| A | ASN295 |
| A | ASP296 |
| A | HOH508 |
| A | HOH530 |
| A | HOH550 |
| A | LEU16 |
| A | HOH582 |
| A | HOH640 |
| A | ASN17 |
| A | PHE58 |
| A | PHE61 |
| A | HIS65 |
| A | THR97 |
| A | THR98 |
| A | LYS100 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P03958","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30721978","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31318636","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IJM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6IV5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30721978","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31318636","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IJN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6J4T","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30721978","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31318636","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6J4T","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30721978","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IJP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"P03958","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
