Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 801 |
| Chain | Residue |
| A | HIS529 |
| A | HIS563 |
| A | ASP564 |
| A | ASP674 |
| A | HOH912 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 802 |
| Chain | Residue |
| A | HOH912 |
| A | ASP564 |
| A | GLU592 |
| A | HOH901 |
| A | HOH908 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| B | HIS529 |
| B | HIS563 |
| B | ASP564 |
| B | ASP674 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 802 |
| Chain | Residue |
| B | ASP564 |
| B | GLU592 |
| B | HOH902 |
| B | HOH904 |
| B | HOH918 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue AEL B 803 |
| Chain | Residue |
| B | TYR524 |
| B | LEU675 |
| B | ILE692 |
| B | TYR693 |
| B | MET713 |
| B | GLY725 |
| B | GLN726 |
| B | PHE729 |
| B | HOH903 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS563-TYR574 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 317 |
| Details | Domain: {"description":"PDEase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01192","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
