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6II6

Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
B0004197molecular_functioncysteine-type endopeptidase activity
C0000139cellular_componentGolgi membrane
C0003924molecular_functionGTPase activity
C0005515molecular_functionprotein binding
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005794cellular_componentGolgi apparatus
C0005886cellular_componentplasma membrane
C0006886biological_processintracellular protein transport
C0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C0015031biological_processprotein transport
C0016192biological_processvesicle-mediated transport
C0048471cellular_componentperinuclear region of cytoplasm
C0070062cellular_componentextracellular exosome
D0000139cellular_componentGolgi membrane
D0003924molecular_functionGTPase activity
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005794cellular_componentGolgi apparatus
D0005886cellular_componentplasma membrane
D0006886biological_processintracellular protein transport
D0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
D0015031biological_processprotein transport
D0016192biological_processvesicle-mediated transport
D0048471cellular_componentperinuclear region of cytoplasm
D0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues25
Detailsbinding site for residue GTP C 1001
ChainResidue
CASP26
CGLY70
CASN126
CLYS127
CASP129
CLEU130
CCYS159
CALA160
CTHR161
CMG1002
CHOH1106
CALA27
CHOH1111
CHOH1119
CHOH1120
CHOH1128
CHOH1142
CHOH1148
CALA28
CGLY29
CLYS30
CTHR31
CTHR32
CTHR45
CTHR48

site_idAC2
Number of Residues5
Detailsbinding site for residue MG C 1002
ChainResidue
CTHR31
CTHR48
CGTP1001
CHOH1119
CHOH1120

site_idAC3
Number of Residues22
Detailsbinding site for residue GTP D 1001
ChainResidue
DASP26
DALA27
DALA28
DGLY29
DLYS30
DTHR31
DTHR32
DTHR45
DPRO47
DTHR48
DGLY70
DASN126
DLYS127
DASP129
DCYS159
DALA160
DTHR161
DMG1002
DHOH1112
DHOH1115
DHOH1120
DHOH1122

site_idAC4
Number of Residues5
Detailsbinding site for residue MG D 1002
ChainResidue
DTHR31
DTHR48
DGTP1001
DHOH1115
DHOH1120

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
CGLY24
CASP67
CASN126
DGLY24
DASP67
DASN126

219515

PDB entries from 2024-05-08

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