6II6
Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0000139 | cellular_component | Golgi membrane |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005794 | cellular_component | Golgi apparatus |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006886 | biological_process | intracellular protein transport |
| C | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| C | 0048471 | cellular_component | perinuclear region of cytoplasm |
| C | 0070062 | cellular_component | extracellular exosome |
| D | 0000139 | cellular_component | Golgi membrane |
| D | 0003924 | molecular_function | GTPase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005525 | molecular_function | GTP binding |
| D | 0005794 | cellular_component | Golgi apparatus |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006886 | biological_process | intracellular protein transport |
| D | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| D | 0048471 | cellular_component | perinuclear region of cytoplasm |
| D | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue GTP C 1001 |
| Chain | Residue |
| C | ASP26 |
| C | GLY70 |
| C | ASN126 |
| C | LYS127 |
| C | ASP129 |
| C | LEU130 |
| C | CYS159 |
| C | ALA160 |
| C | THR161 |
| C | MG1002 |
| C | HOH1106 |
| C | ALA27 |
| C | HOH1111 |
| C | HOH1119 |
| C | HOH1120 |
| C | HOH1128 |
| C | HOH1142 |
| C | HOH1148 |
| C | ALA28 |
| C | GLY29 |
| C | LYS30 |
| C | THR31 |
| C | THR32 |
| C | THR45 |
| C | THR48 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 1002 |
| Chain | Residue |
| C | THR31 |
| C | THR48 |
| C | GTP1001 |
| C | HOH1119 |
| C | HOH1120 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue GTP D 1001 |
| Chain | Residue |
| D | ASP26 |
| D | ALA27 |
| D | ALA28 |
| D | GLY29 |
| D | LYS30 |
| D | THR31 |
| D | THR32 |
| D | THR45 |
| D | PRO47 |
| D | THR48 |
| D | GLY70 |
| D | ASN126 |
| D | LYS127 |
| D | ASP129 |
| D | CYS159 |
| D | ALA160 |
| D | THR161 |
| D | MG1002 |
| D | HOH1112 |
| D | HOH1115 |
| D | HOH1120 |
| D | HOH1122 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 1002 |
| Chain | Residue |
| D | THR31 |
| D | THR48 |
| D | GTP1001 |
| D | HOH1115 |
| D | HOH1120 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
