6II6

Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
B	0004197	molecular_function	cysteine-type endopeptidase activity
C	0000139	cellular_component	Golgi membrane
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0005886	cellular_component	plasma membrane
C	0006886	biological_process	intracellular protein transport
C	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C	0015031	biological_process	protein transport
C	0016192	biological_process	vesicle-mediated transport
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0070062	cellular_component	extracellular exosome
D	0000139	cellular_component	Golgi membrane
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0005886	cellular_component	plasma membrane
D	0006886	biological_process	intracellular protein transport
D	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
D	0015031	biological_process	protein transport
D	0016192	biological_process	vesicle-mediated transport
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	binding site for residue GTP C 1001

Chain	Residue
C	ASP26
C	GLY70
C	ASN126
C	LYS127
C	ASP129
C	LEU130
C	CYS159
C	ALA160
C	THR161
C	MG1002
C	HOH1106
C	ALA27
C	HOH1111
C	HOH1119
C	HOH1120
C	HOH1128
C	HOH1142
C	HOH1148
C	ALA28
C	GLY29
C	LYS30
C	THR31
C	THR32
C	THR45
C	THR48

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG C 1002

Chain	Residue
C	THR31
C	THR48
C	GTP1001
C	HOH1119
C	HOH1120

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site_id	AC3
Number of Residues	22
Details	binding site for residue GTP D 1001

Chain	Residue
D	ASP26
D	ALA27
D	ALA28
D	GLY29
D	LYS30
D	THR31
D	THR32
D	THR45
D	PRO47
D	THR48
D	GLY70
D	ASN126
D	LYS127
D	ASP129
D	CYS159
D	ALA160
D	THR161
D	MG1002
D	HOH1112
D	HOH1115
D	HOH1120
D	HOH1122

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG D 1002

Chain	Residue
D	THR31
D	THR48
D	GTP1001
D	HOH1115
D	HOH1120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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