6I5Q

Papaver somniferum O-methyltransferase 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0008171	molecular_function	O-methyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0009708	biological_process	benzyl isoquinoline alkaloid biosynthetic process
A	0009820	biological_process	alkaloid metabolic process
A	0030762	molecular_function	tetrahydrocolumbamine 2-O-methyltransferase activity
A	0030777	molecular_function	(S)-scoulerine 9-O-methyltransferase activity
A	0032259	biological_process	methylation
A	0046983	molecular_function	protein dimerization activity
B	0008168	molecular_function	methyltransferase activity
B	0008171	molecular_function	O-methyltransferase activity
B	0009058	biological_process	biosynthetic process
B	0009708	biological_process	benzyl isoquinoline alkaloid biosynthetic process
B	0009820	biological_process	alkaloid metabolic process
B	0030762	molecular_function	tetrahydrocolumbamine 2-O-methyltransferase activity
B	0030777	molecular_function	(S)-scoulerine 9-O-methyltransferase activity
B	0032259	biological_process	methylation
B	0046983	molecular_function	protein dimerization activity
C	0008168	molecular_function	methyltransferase activity
C	0008171	molecular_function	O-methyltransferase activity
C	0009058	biological_process	biosynthetic process
C	0009708	biological_process	benzyl isoquinoline alkaloid biosynthetic process
C	0009820	biological_process	alkaloid metabolic process
C	0030762	molecular_function	tetrahydrocolumbamine 2-O-methyltransferase activity
C	0030777	molecular_function	(S)-scoulerine 9-O-methyltransferase activity
C	0032259	biological_process	methylation
C	0046983	molecular_function	protein dimerization activity
D	0008168	molecular_function	methyltransferase activity
D	0008171	molecular_function	O-methyltransferase activity
D	0009058	biological_process	biosynthetic process
D	0009708	biological_process	benzyl isoquinoline alkaloid biosynthetic process
D	0009820	biological_process	alkaloid metabolic process
D	0030762	molecular_function	tetrahydrocolumbamine 2-O-methyltransferase activity
D	0030777	molecular_function	(S)-scoulerine 9-O-methyltransferase activity
D	0032259	biological_process	methylation
D	0046983	molecular_function	protein dimerization activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01020, ECO:0000269|DOI:10.1021/acscatal.9b01038

Chain	Residue	Details
A	HIS296
B	HIS296
C	HIS296
D	HIS296

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0007744|PDB:6I6K, ECO:0007744|PDB:6I6N

Chain	Residue	Details
A	GLU153
B	GLU153
C	GLU153
D	GLU153

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q5C9L7

Chain	Residue	Details
A	MET207
B	MET207
C	MET207
D	MET207

---

site_id	SWS_FT_FI4
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|DOI:10.1021/acscatal.9b01038, ECO:0007744|PDB:6I6K, ECO:0007744|PDB:6I6N

Chain	Residue	Details
A	SER211
B	HIS296
C	SER211
C	GLY235
C	ASP278
C	LYS292
C	HIS296
D	SER211
D	GLY235
D	ASP278
D	LYS292
A	GLY235
D	HIS296
A	ASP278
A	LYS292
A	HIS296
B	SER211
B	GLY235
B	ASP278
B	LYS292

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site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01020, ECO:0000269|DOI:10.1021/acscatal.9b01038, ECO:0007744|PDB:6I6K, ECO:0007744|PDB:6I6N

Chain	Residue	Details
A	ASP258
B	ASP258
C	ASP258
D	ASP258

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