Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue H3E A 501 |
| Chain | Residue |
| A | LEU167 |
| A | LEU295 |
| A | HOH653 |
| A | PHE172 |
| A | ALA189 |
| A | LYS191 |
| A | PHE241 |
| A | GLU242 |
| A | LEU244 |
| A | GLY245 |
| A | GLU292 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | HIS233 |
| A | HIS234 |
| A | HOH612 |
| A | HOH621 |
| A | HOH774 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | SER220 |
| A | LYS322 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ARG160 |
| A | HOH605 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | LEU243 |
| A | LEU244 |
| A | VAL297 |
| A | GLN298 |
| A | SER299 |
| A | EDO506 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | LEU244 |
| A | GLY245 |
| A | LEU246 |
| A | EDO505 |
| A | HOH644 |
| A | HOH648 |
| A | HOH723 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | ILE252 |
| A | ASN255 |
| A | LEU258 |
| A | PRO259 |
| A | PHE260 |
| A | HOH622 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | PRO259 |
| A | PHE260 |
| A | ARG261 |
| A | LEU262 |
| A | TYR373 |
| A | LEU441 |
| A | EDO509 |
| A | HOH618 |
| A | HOH710 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | PRO259 |
| A | EDO508 |
| A | HOH618 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | LEU262 |
| A | ASP263 |
| A | ARG266 |
| A | GLU446 |
| A | HOH731 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | MET440 |
| A | LEU441 |
| A | SER442 |
| A | GLN443 |
| A | HOH771 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | TRP419 |
| A | ASP420 |
| A | SER423 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | CYS200 |
| A | GLU201 |
| A | ARG204 |
| A | LYS385 |
| A | LYS410 |
| A | TYR411 |
| A | HOH893 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGKVVeCidhkaggrh.........VAVK |
| Chain | Residue | Details |
| A | LEU167-LYS191 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LtHtDLKpeNILF |
| Chain | Residue | Details |
| A | LEU284-PHE296 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
