Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6I08

THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W

Functional Information from GO Data
ChainGOidnamespacecontents
A0004888molecular_functiontransmembrane signaling receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0006811biological_processmonoatomic ion transport
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
B0004888molecular_functiontransmembrane signaling receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0006811biological_processmonoatomic ion transport
B0016020cellular_componentmembrane
B0034220biological_processmonoatomic ion transmembrane transport
C0004888molecular_functiontransmembrane signaling receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0006811biological_processmonoatomic ion transport
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
D0004888molecular_functiontransmembrane signaling receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0006811biological_processmonoatomic ion transport
D0016020cellular_componentmembrane
D0034220biological_processmonoatomic ion transmembrane transport
E0004888molecular_functiontransmembrane signaling receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0006811biological_processmonoatomic ion transport
E0016020cellular_componentmembrane
E0034220biological_processmonoatomic ion transmembrane transport
Functional Information from PDB Data
site_idAC1
Number of Residues1
Detailsbinding site for residue CL D 401
ChainResidue
DPHE78

site_idAC2
Number of Residues6
Detailsbinding site for residue PLC D 402
ChainResidue
DPHE121
DTYR194
DLEU203
DTYR254
DILE258
DASN307

site_idAC3
Number of Residues3
Detailsbinding site for residue LMT D 403
ChainResidue
DILE240
AILE240
CILE240

site_idAC4
Number of Residues2
Detailsbinding site for residue NA D 404
ChainResidue
DPRO74
DILE76

site_idAC5
Number of Residues1
Detailsbinding site for residue CL A 401
ChainResidue
APHE78

site_idAC6
Number of Residues5
Detailsbinding site for residue PLC A 402
ChainResidue
APHE121
ATYR194
ATYR254
AILE258
AASN307

site_idAC7
Number of Residues1
Detailsbinding site for residue NA A 404
ChainResidue
ATHR226

site_idAC8
Number of Residues1
Detailsbinding site for residue NA A 405
ChainResidue
APRO74

site_idAC9
Number of Residues1
Detailsbinding site for residue CL B 401
ChainResidue
BPHE78

site_idAD1
Number of Residues6
Detailsbinding site for residue PLC B 402
ChainResidue
BPHE121
BTYR194
BLEU203
BTYR254
BILE258
BASN307

site_idAD2
Number of Residues1
Detailsbinding site for residue NA B 403
ChainResidue
BPRO74

site_idAD3
Number of Residues1
Detailsbinding site for residue CL C 401
ChainResidue
CPHE78

site_idAD4
Number of Residues5
Detailsbinding site for residue PLC C 402
ChainResidue
CPHE121
CTYR194
CTYR254
CILE258
CASN307

site_idAD5
Number of Residues2
Detailsbinding site for residue NA C 403
ChainResidue
CPRO74
CARG77

site_idAD6
Number of Residues1
Detailsbinding site for residue CL E 401
ChainResidue
EPHE78

site_idAD7
Number of Residues5
Detailsbinding site for residue PLC E 402
ChainResidue
EPHE121
ETYR194
ETYR254
EILE258
EASN307

site_idAD8
Number of Residues1
Detailsbinding site for residue NA E 403
ChainResidue
EPRO74

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues990
DetailsTOPO_DOM: Periplasmic => ECO:0000255
ChainResidueDetails
DGLN2-GLN193
EASN245-MET252
DASN245-MET252
AGLN2-GLN193
AASN245-MET252
BGLN2-GLN193
BASN245-MET252
CGLN2-GLN193
CASN245-MET252
EGLN2-GLN193

site_idSWS_FT_FI2
Number of Residues530
DetailsTRANSMEM: Helical
ChainResidueDetails
DTYR194-PHE216
BSER220-THR244
BTHR253-VAL281
BPRO285-PHE317
CTYR194-PHE216
CSER220-THR244
CTHR253-VAL281
CPRO285-PHE317
ETYR194-PHE216
ESER220-THR244
ETHR253-VAL281
DSER220-THR244
EPRO285-PHE317
DTHR253-VAL281
DPRO285-PHE317
ATYR194-PHE216
ASER220-THR244
ATHR253-VAL281
APRO285-PHE317
BTYR194-PHE216

site_idSWS_FT_FI3
Number of Residues20
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
DTRP217-THR219
EGLU282-GLN284
DGLU282-GLN284
ATRP217-THR219
AGLU282-GLN284
BTRP217-THR219
BGLU282-GLN284
CTRP217-THR219
CGLU282-GLN284
ETRP217-THR219

223166

PDB entries from 2024-07-31

PDB statisticsPDBj update infoContact PDBjnumon