6I08
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C-I201W
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0004888 | molecular_function | transmembrane signaling receptor activity |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0004888 | molecular_function | transmembrane signaling receptor activity |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| E | 0004888 | molecular_function | transmembrane signaling receptor activity |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0005230 | molecular_function | extracellular ligand-gated monoatomic ion channel activity |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0016020 | cellular_component | membrane |
| E | 0034220 | biological_process | monoatomic ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 401 |
| Chain | Residue |
| D | PHE78 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue PLC D 402 |
| Chain | Residue |
| D | PHE121 |
| D | TYR194 |
| D | LEU203 |
| D | TYR254 |
| D | ILE258 |
| D | ASN307 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue LMT D 403 |
| Chain | Residue |
| D | ILE240 |
| A | ILE240 |
| C | ILE240 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue NA D 404 |
| Chain | Residue |
| D | PRO74 |
| D | ILE76 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | PHE78 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PLC A 402 |
| Chain | Residue |
| A | PHE121 |
| A | TYR194 |
| A | TYR254 |
| A | ILE258 |
| A | ASN307 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 404 |
| Chain | Residue |
| A | THR226 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 405 |
| Chain | Residue |
| A | PRO74 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | PHE78 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue PLC B 402 |
| Chain | Residue |
| B | PHE121 |
| B | TYR194 |
| B | LEU203 |
| B | TYR254 |
| B | ILE258 |
| B | ASN307 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue NA B 403 |
| Chain | Residue |
| B | PRO74 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 401 |
| Chain | Residue |
| C | PHE78 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PLC C 402 |
| Chain | Residue |
| C | PHE121 |
| C | TYR194 |
| C | TYR254 |
| C | ILE258 |
| C | ASN307 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue NA C 403 |
| Chain | Residue |
| C | PRO74 |
| C | ARG77 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 401 |
| Chain | Residue |
| E | PHE78 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue PLC E 402 |
| Chain | Residue |
| E | PHE121 |
| E | TYR194 |
| E | TYR254 |
| E | ILE258 |
| E | ASN307 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue NA E 403 |
| Chain | Residue |
| E | PRO74 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 370 |
| Details | Transmembrane: {"description":"Helical"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
