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6HYM

Structure of PCM1 LIR motif bound to GABARAP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000045biological_processautophagosome assembly
A0000139cellular_componentGolgi membrane
A0000226biological_processmicrotubule cytoskeleton organization
A0000421cellular_componentautophagosome membrane
A0000423biological_processmitophagy
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005776cellular_componentautophagosome
A0005790cellular_componentsmooth endoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0005875cellular_componentmicrotubule associated complex
A0005886cellular_componentplasma membrane
A0005930cellular_componentaxoneme
A0006605biological_processprotein targeting
A0006914biological_processautophagy
A0006915biological_processapoptotic process
A0006995biological_processcellular response to nitrogen starvation
A0007268biological_processchemical synaptic transmission
A0008017molecular_functionmicrotubule binding
A0008429molecular_functionphosphatidylethanolamine binding
A0008625biological_processextrinsic apoptotic signaling pathway via death domain receptors
A0012505cellular_componentendomembrane system
A0015031biological_processprotein transport
A0015629cellular_componentactin cytoskeleton
A0016020cellular_componentmembrane
A0031410cellular_componentcytoplasmic vesicle
A0031625molecular_functionubiquitin protein ligase binding
A0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
A0035020biological_processregulation of Rac protein signal transduction
A0048487molecular_functionbeta-tubulin binding
A0050811molecular_functionGABA receptor binding
A0097225cellular_componentsperm midpiece
A0097352biological_processautophagosome maturation
A0098696biological_processregulation of neurotransmitter receptor localization to postsynaptic specialization membrane
A0098982cellular_componentGABA-ergic synapse
A1902524biological_processpositive regulation of protein K48-linked ubiquitination
B0000045biological_processautophagosome assembly
B0000139cellular_componentGolgi membrane
B0000226biological_processmicrotubule cytoskeleton organization
B0000421cellular_componentautophagosome membrane
B0000423biological_processmitophagy
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005764cellular_componentlysosome
B0005776cellular_componentautophagosome
B0005790cellular_componentsmooth endoplasmic reticulum
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0005875cellular_componentmicrotubule associated complex
B0005886cellular_componentplasma membrane
B0005930cellular_componentaxoneme
B0006605biological_processprotein targeting
B0006914biological_processautophagy
B0006915biological_processapoptotic process
B0006995biological_processcellular response to nitrogen starvation
B0007268biological_processchemical synaptic transmission
B0008017molecular_functionmicrotubule binding
B0008429molecular_functionphosphatidylethanolamine binding
B0008625biological_processextrinsic apoptotic signaling pathway via death domain receptors
B0012505cellular_componentendomembrane system
B0015031biological_processprotein transport
B0015629cellular_componentactin cytoskeleton
B0016020cellular_componentmembrane
B0031410cellular_componentcytoplasmic vesicle
B0031625molecular_functionubiquitin protein ligase binding
B0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
B0035020biological_processregulation of Rac protein signal transduction
B0048487molecular_functionbeta-tubulin binding
B0050811molecular_functionGABA receptor binding
B0097225cellular_componentsperm midpiece
B0097352biological_processautophagosome maturation
B0098696biological_processregulation of neurotransmitter receptor localization to postsynaptic specialization membrane
B0098982cellular_componentGABA-ergic synapse
B1902524biological_processpositive regulation of protein K48-linked ubiquitination
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue GOL A 201
ChainResidue
ATYR61
AARG65
ALEU76
APHE77
AHOH320
AHOH321

site_idAC2
Number of Residues6
Detailsbinding site for residue GOL A 202
ChainResidue
AARG67
AHOH306
AHOH319
AASP-6
ALEU-5
AVAL-10

site_idAC3
Number of Residues4
Detailsbinding site for residue GOL A 203
ChainResidue
ASER0
AMET1
ALYS2
ALYS35

site_idAC4
Number of Residues6
Detailsbinding site for residue GOL B 201
ChainResidue
BTYR61
BARG65
BLEU76
BHOH310
BHOH322
BHOH348

site_idAC5
Number of Residues3
Detailsbinding site for residue EDO B 202
ChainResidue
BARG22
BPRO26
BSER53

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsSITE: Interaction with LIR (LC3 nteracting Region) motif of ATG3 => ECO:0000269|PubMed:37252361, ECO:0007744|PDB:8AFI
ChainResidueDetails
AGLU17
AARG28
BGLU17
BARG28

site_idSWS_FT_FI2
Number of Residues2
DetailsSITE: Cleavage; by ATG4B => ECO:0000269|PubMed:15169837
ChainResidueDetails
AGLY116
BGLY116

site_idSWS_FT_FI3
Number of Residues2
DetailsLIPID: Phosphatidylserine amidated glycine; alternate => ECO:0000269|PubMed:33909989
ChainResidueDetails
AGLY116
BGLY116

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PDB entries from 2024-11-06

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