Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| B | 0005261 | molecular_function | monoatomic cation channel activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue K A 301 |
| Chain | Residue |
| A | SER267 |
| A | SER267 |
| A | ASP268 |
| A | ASP268 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | LYS165 |
| A | HIS167 |
| A | GLU214 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | ASP113 |
| A | GLU114 |
| A | ASP115 |
| A | HOH430 |
| A | GLY111 |
| A | THR112 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | TYR128 |
| A | GOL306 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | PHE132 |
| A | GOL305 |
| A | HOH464 |
| A | HOH486 |
| B | ASP115 |
| B | GOL307 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | LYS165 |
| A | HIS167 |
| A | ASP189 |
| A | SER209 |
| A | ARG212 |
| A | GLU214 |
| A | ARG217 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 308 |
| Chain | Residue |
| A | THR123 |
| A | ASP126 |
| A | HOH425 |
| A | HOH437 |
| A | HOH474 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue MES A 309 |
| Chain | Residue |
| A | VAL191 |
| A | GLN192 |
| A | ASP194 |
| A | ASP197 |
| A | TRP205 |
| A | HOH401 |
| A | HOH438 |
| B | LEU188 |
| B | HOH462 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 301 |
| Chain | Residue |
| B | LYS165 |
| B | HIS167 |
| B | GLU214 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 302 |
| Chain | Residue |
| B | HIS103 |
| B | THR123 |
| B | PHE133 |
| B | GLN137 |
| B | GOL304 |
| B | HOH412 |
| B | HOH444 |
| B | HOH461 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | GLN124 |
| B | GLU125 |
| B | ASP143 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| B | ASP126 |
| B | GOL302 |
| B | HOH478 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 305 |
| Chain | Residue |
| B | GLU125 |
| B | TYR128 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 306 |
| Chain | Residue |
| B | GLY108 |
| B | TYR109 |
| B | SER110 |
| B | GLU114 |
| B | CYS119 |
| B | SER120 |
| B | HOH416 |
| B | HOH428 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 307 |
| Chain | Residue |
| A | GOL306 |
| B | MES308 |
| B | HOH447 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue MES B 308 |
| Chain | Residue |
| A | LYS201 |
| B | LYS102 |
| B | ASP113 |
| B | ASP115 |
| B | ASP116 |
| B | SER118 |
| B | TYR264 |
| B | PHE265 |
| B | GOL307 |
| B | HOH418 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue MES B 309 |
| Chain | Residue |
| A | CYS190 |
| B | HIS167 |
| B | LYS169 |
| B | LYS170 |
| B | GLU187 |
| B | ASP189 |
| B | ARG217 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Region: {"description":"Extracellular/lumenal pore loop","evidences":[{"source":"UniProtKB","id":"Q9GZU1","evidenceCode":"ECO:0000250"}]} |
