Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0004649 | molecular_function | poly(ADP-ribose) glycohydrolase activity |
A | 0005634 | cellular_component | nucleus |
A | 0005694 | cellular_component | chromosome |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0005759 | cellular_component | mitochondrial matrix |
A | 0006281 | biological_process | DNA repair |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0060546 | biological_process | negative regulation of necroptotic process |
A | 0140290 | biological_process | peptidyl-serine ADP-deribosylation |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0004649 | molecular_function | poly(ADP-ribose) glycohydrolase activity |
B | 0005634 | cellular_component | nucleus |
B | 0005694 | cellular_component | chromosome |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0005759 | cellular_component | mitochondrial matrix |
B | 0006281 | biological_process | DNA repair |
B | 0016787 | molecular_function | hydrolase activity |
B | 0046872 | molecular_function | metal ion binding |
B | 0060546 | biological_process | negative regulation of necroptotic process |
B | 0140290 | biological_process | peptidyl-serine ADP-deribosylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | binding site for residue MG A 401 |
Chain | Residue |
A | THR62 |
A | ASP63 |
A | ASP64 |
A | ASP305 |
A | R5I403 |
A | R7I404 |
A | HOH627 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MG A 402 |
Chain | Residue |
A | ASP305 |
A | THR306 |
A | R5I403 |
A | R7I404 |
A | GLU33 |
A | ASP303 |
site_id | AC3 |
Number of Residues | 29 |
Details | binding site for residue R5I A 403 |
Chain | Residue |
A | GLU33 |
A | ASP63 |
A | ASP64 |
A | GLY101 |
A | GLY103 |
A | ALA104 |
A | GLY105 |
A | VAL106 |
A | PHE129 |
A | GLY133 |
A | SER134 |
A | TYR135 |
A | GLY136 |
A | ASN137 |
A | GLY138 |
A | HIS168 |
A | ILE260 |
A | ASP303 |
A | ASP305 |
A | THR306 |
A | MG401 |
A | MG402 |
A | R7I404 |
A | HOH506 |
A | HOH514 |
A | HOH521 |
A | HOH575 |
A | HOH597 |
B | HOH620 |
site_id | AC4 |
Number of Residues | 29 |
Details | binding site for residue R7I A 404 |
Chain | Residue |
A | GLU33 |
A | ASP63 |
A | ASP64 |
A | GLY101 |
A | GLY103 |
A | GLY105 |
A | VAL106 |
A | PHE129 |
A | GLY133 |
A | SER134 |
A | TYR135 |
A | GLY136 |
A | ASN137 |
A | GLY138 |
A | HIS168 |
A | ILE260 |
A | ASP303 |
A | ASP305 |
A | THR306 |
A | MG401 |
A | MG402 |
A | R5I403 |
A | HOH506 |
A | HOH510 |
A | HOH514 |
A | HOH521 |
A | HOH575 |
A | HOH627 |
B | HOH620 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue GOL A 405 |
Chain | Residue |
A | ASP80 |
A | ASP155 |
A | GLN352 |
A | HOH570 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue GOL A 406 |
Chain | Residue |
A | ASN152 |
A | GLN154 |
A | ASP155 |
A | LYS158 |
A | HOH593 |
B | GLN123 |
B | ARG126 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue GOL A 407 |
Chain | Residue |
A | ASN175 |
A | GLU209 |
A | PHE231 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue GOL A 408 |
Chain | Residue |
A | GLU337 |
A | GLU340 |
B | SER11 |
B | LEU12 |
B | ALA13 |
site_id | AC9 |
Number of Residues | 6 |
Details | binding site for residue GOL A 409 |
Chain | Residue |
A | GLU97 |
A | THR99 |
A | ARG100 |
A | HOH578 |
B | THR99 |
B | HOH528 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue ACT A 410 |
Chain | Residue |
A | PHE60 |
A | HOH502 |
A | HOH586 |
A | GLU31 |
A | THR58 |
A | LEU59 |
site_id | AD2 |
Number of Residues | 7 |
Details | binding site for residue MG B 401 |
Chain | Residue |
B | THR62 |
B | ASP63 |
B | ASP64 |
B | ASP305 |
B | R5I403 |
B | R7I404 |
B | HOH616 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue MG B 402 |
Chain | Residue |
B | GLU33 |
B | ASP303 |
B | ASP305 |
B | THR306 |
B | R5I403 |
B | R7I404 |
site_id | AD4 |
Number of Residues | 30 |
Details | binding site for residue R5I B 403 |
Chain | Residue |
A | ASP42 |
A | HOH518 |
B | GLU33 |
B | ASP63 |
B | ASP64 |
B | GLY101 |
B | GLY103 |
B | GLY105 |
B | VAL106 |
B | PHE129 |
B | GLY133 |
B | SER134 |
B | TYR135 |
B | GLY136 |
B | ASN137 |
B | GLY138 |
B | HIS168 |
B | ILE260 |
B | ASP303 |
B | ASP305 |
B | THR306 |
B | MG401 |
B | MG402 |
B | R7I404 |
B | HOH512 |
B | HOH526 |
B | HOH560 |
B | HOH567 |
B | HOH587 |
B | HOH644 |
site_id | AD5 |
Number of Residues | 31 |
Details | binding site for residue R7I B 404 |
Chain | Residue |
A | ALA37 |
A | HOH518 |
B | GLU33 |
B | ASP63 |
B | ASP64 |
B | GLY101 |
B | GLY103 |
B | GLY105 |
B | VAL106 |
B | PHE129 |
B | GLY133 |
B | SER134 |
B | TYR135 |
B | GLY136 |
B | ASN137 |
B | GLY138 |
B | HIS168 |
B | ILE260 |
B | ASP303 |
B | ASP305 |
B | THR306 |
B | MG401 |
B | MG402 |
B | R5I403 |
B | HOH512 |
B | HOH524 |
B | HOH526 |
B | HOH560 |
B | HOH567 |
B | HOH587 |
B | HOH644 |
site_id | AD6 |
Number of Residues | 6 |
Details | binding site for residue GOL B 405 |
Chain | Residue |
B | SER244 |
B | SER245 |
B | ASN246 |
B | HIS275 |
B | PRO281 |
B | HOH514 |
site_id | AD7 |
Number of Residues | 5 |
Details | binding site for residue GOL B 406 |
Chain | Residue |
B | GLY190 |
B | GLU191 |
B | TYR318 |
B | TYR319 |
B | HOH534 |
site_id | AD8 |
Number of Residues | 4 |
Details | binding site for residue GOL B 407 |
Chain | Residue |
B | ASN175 |
B | GLU209 |
B | PHE231 |
B | HOH627 |
site_id | AD9 |
Number of Residues | 4 |
Details | binding site for residue GOL B 408 |
Chain | Residue |
B | ARG126 |
B | GLN165 |
B | HOH510 |
B | HOH569 |
site_id | AE1 |
Number of Residues | 4 |
Details | binding site for residue GOL B 409 |
Chain | Residue |
B | GLU97 |
B | ARG100 |
B | HOH527 |
B | HOH528 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP26 | |
B | ASP26 | |
Chain | Residue | Details |
A | GLU33 | |
A | ASP64 | |
A | ASP303 | |
A | ASP305 | |
B | GLU33 | |
B | ASP64 | |
B | ASP303 | |
B | ASP305 | |
Chain | Residue | Details |
A | THR62 | |
B | HIS168 | |
B | ILE260 | |
B | THR306 | |
A | ASP63 | |
A | LYS132 | |
A | HIS168 | |
A | ILE260 | |
A | THR306 | |
B | THR62 | |
B | ASP63 | |
B | LYS132 | |
Chain | Residue | Details |
A | GLU33 | |
B | GLU33 | |