6HKW
Crystal structure of human SDS22
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005694 | cellular_component | chromosome |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0019888 | molecular_function | protein phosphatase regulator activity |
| A | 0030234 | molecular_function | enzyme regulator activity |
| A | 0035307 | biological_process | obsolete positive regulation of protein dephosphorylation |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005694 | cellular_component | chromosome |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0019888 | molecular_function | protein phosphatase regulator activity |
| B | 0030234 | molecular_function | enzyme regulator activity |
| B | 0035307 | biological_process | obsolete positive regulation of protein dephosphorylation |
| B | 0070062 | cellular_component | extracellular exosome |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005694 | cellular_component | chromosome |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0019888 | molecular_function | protein phosphatase regulator activity |
| C | 0030234 | molecular_function | enzyme regulator activity |
| C | 0035307 | biological_process | obsolete positive regulation of protein dephosphorylation |
| C | 0070062 | cellular_component | extracellular exosome |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005694 | cellular_component | chromosome |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0019888 | molecular_function | protein phosphatase regulator activity |
| D | 0030234 | molecular_function | enzyme regulator activity |
| D | 0035307 | biological_process | obsolete positive regulation of protein dephosphorylation |
| D | 0070062 | cellular_component | extracellular exosome |
| E | 0005515 | molecular_function | protein binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0005694 | cellular_component | chromosome |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0019888 | molecular_function | protein phosphatase regulator activity |
| E | 0030234 | molecular_function | enzyme regulator activity |
| E | 0035307 | biological_process | obsolete positive regulation of protein dephosphorylation |
| E | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | LYS133 |
| A | ARG155 |
| A | SO4402 |
| B | ARG197 |
| B | ARG199 |
| B | LYS219 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| B | LYS219 |
| B | ARG241 |
| A | LYS133 |
| A | SO4401 |
| B | ARG199 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG197 |
| A | ARG199 |
| A | LYS219 |
| B | LYS133 |
| B | ARG155 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | ARG199 |
| A | LYS219 |
| A | ARG241 |
| B | LYS133 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG155 |
| A | LYS175 |
| A | ARG197 |
| B | ARG155 |
| B | SO4401 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ARG340 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| A | SO4405 |
| B | ARG155 |
| B | LYS175 |
| B | ARG197 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ARG340 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | GLU180 |
| B | ASN181 |
| B | SER183 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 401 |
| Chain | Residue |
| C | ARG155 |
| C | LYS175 |
| C | ARG197 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| C | ARG199 |
| C | LYS219 |
| C | ARG241 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| C | LYS133 |
| C | ARG155 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| B | ARG165 |
| C | GLU180 |
| C | ASN181 |
| C | LEU182 |
| C | SER183 |
| C | ASN203 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 401 |
| Chain | Residue |
| D | ARG155 |
| D | LYS175 |
| D | ARG197 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | ARG199 |
| D | LYS219 |
| D | ARG241 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 403 |
| Chain | Residue |
| D | LYS133 |
| D | ARG155 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 404 |
| Chain | Residue |
| D | GLU180 |
| D | ASN181 |
| D | LEU182 |
| D | SER183 |
| D | ASN203 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 401 |
| Chain | Residue |
| E | ARG155 |
| E | LYS175 |
| E | ARG197 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 402 |
| Chain | Residue |
| E | ARG199 |
| E | LYS219 |
| E | ARG241 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 E 403 |
| Chain | Residue |
| D | ARG165 |
| E | GLU180 |
| E | ASN181 |
| E | SER183 |
| E | ASN203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330 |
| Chain | Residue | Details |
| A | ALA2 | |
| B | ALA2 | |
| C | ALA2 | |
| D | ALA2 | |
| E | ALA2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER12 | |
| B | SER12 | |
| C | SER12 | |
| D | SER12 | |
| E | SER12 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| A | SER24 | |
| B | SER24 | |
| C | SER24 | |
| D | SER24 | |
| E | SER24 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER27 | |
| B | SER27 | |
| C | SER27 | |
| D | SER27 | |
| E | SER27 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER44 | |
| E | SER47 | |
| A | SER47 | |
| B | SER44 | |
| B | SER47 | |
| C | SER44 | |
| C | SER47 | |
| D | SER44 | |
| D | SER47 | |
| E | SER44 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER322 | |
| B | SER322 | |
| C | SER322 | |
| D | SER322 | |
| E | SER322 |
