6HG7

Crystal structure of a collagen II fragment containing the binding site of PEDF and COMP, (POG)4-LKG HRG FTG LQG-POG(4)

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 101

Chain	Residue
A	NH237
B	HYP2
C	ARG17
C	PHE19
C	THR20
C	HOH228

---

site_id	AC2
Number of Residues	5
Details	binding site for Di-peptide ACE B 0 and PRO B 1

Chain	Residue
B	HOH201
C	ACE0
A	ACE0
A	NH237
B	HYP2

---

site_id	AC3
Number of Residues	9
Details	binding site for Di-peptide PRO B 1 and HYP B 2

Chain	Residue
A	ACE0
A	NH237
A	SO4101
B	ACE0
B	GLY3
B	HOH201
B	HOH203
C	PRO1
C	HYP35

---

site_id	AC4
Number of Residues	10
Details	binding site for Di-peptide HYP B 2 and GLY B 3

Chain	Residue
A	ACE0
A	PRO1
A	SO4101
B	PRO1
B	PRO4
B	HOH203
B	HOH211
C	PRO1
C	GLY3
C	HYP35

---

site_id	AC5
Number of Residues	11
Details	binding site for Di-peptide PRO B 4 and HYP B 5

Chain	Residue
A	HYP2
A	GLY3
B	GLY3
B	GLY6
B	GLN23
B	HOH209
B	HOH220
C	GLY3
C	PRO4
C	HYP32
C	HOH211

---

site_id	AC6
Number of Residues	12
Details	binding site for Di-peptide HYP B 5 and GLY B 6

Chain	Residue
A	GLY3
A	PRO4
B	PRO4
B	PRO7
B	HOH209
B	HOH212
B	HOH220
C	PRO4
C	GLY6
C	PRO7
C	HYP32
C	HOH211

---

site_id	AC7
Number of Residues	8
Details	binding site for Di-peptide PRO B 10 and HYP B 11

Chain	Residue
A	HYP8
A	GLY9
B	GLY9
B	GLY12
B	HOH208
B	HOH228
C	GLY9
C	PRO10

---

site_id	AC8
Number of Residues	9
Details	binding site for Di-peptide HYP B 11 and GLY B 12

Chain	Residue
A	GLY9
A	PRO10
B	PRO10
B	LEU13
B	HOH208
B	HOH219
B	HOH228
C	PRO10
C	GLY12

---

site_id	AC9
Number of Residues	10
Details	binding site for Di-peptide PRO B 31 and HYP B 32

Chain	Residue
A	GLY27
A	HYP29
A	GLY30
B	HYP26
B	GLY30
B	GLY33
B	HOH206
B	HOH212
C	GLY30
C	PRO31

---

site_id	AD1
Number of Residues	11
Details	binding site for Di-peptide HYP B 32 and GLY B 33

Chain	Residue
A	GLY30
A	PRO31
B	HYP26
B	PRO31
B	PRO34
B	HOH205
B	HOH206
B	HOH212
C	PRO31
C	GLY33
C	PRO34

---

site_id	AD2
Number of Residues	9
Details	binding site for Di-peptide PRO B 34 and HYP B 35

Chain	Residue
C	PRO34
A	HYP32
A	GLY33
B	GLN23
B	GLY33
B	GLY36
B	HOH202
B	HOH207
C	GLY33

---

site_id	AD3
Number of Residues	11
Details	binding site for Di-peptide HYP B 35 and GLY B 36

Chain	Residue
A	GLY33
A	PRO34
B	GLN23
B	PRO34
B	NH237
B	HOH202
B	HOH207
B	HOH217
B	HOH224
C	PRO34
C	GLY36

---

site_id	AD4
Number of Residues	10
Details	binding site for Di-peptide GLY B 36 and NH2 B 37

Chain	Residue
A	GLY33
A	PRO34
A	HOH216
B	PRO34
B	HYP35
B	HOH217
B	HOH224
B	HOH226
C	PRO34
C	GLY36

---

site_id	AD5
Number of Residues	7
Details	binding site for Di-peptide ACE C 0 and PRO C 1

Chain	Residue
A	ACE0
A	PRO1
B	ACE0
B	HYP2
B	GLY3
C	HYP2
C	GLY3

---

site_id	AD6
Number of Residues	8
Details	binding site for Di-peptide PRO C 1 and HYP C 2

Chain	Residue
A	ACE0
A	PRO1
B	HYP2
B	GLY3
C	ACE0
C	GLY3
C	HOH204
C	HOH207

---

site_id	AD7
Number of Residues	8
Details	binding site for Di-peptide HYP C 2 and GLY C 3

Chain	Residue
A	PRO1
A	GLY3
B	GLY3
B	PRO4
C	PRO1
C	PRO4
C	HOH204
C	HOH207

---

site_id	AD8
Number of Residues	11
Details	binding site for Di-peptide PRO C 4 and HYP C 5

Chain	Residue
A	GLY3
A	PRO4
A	HYP5
B	HYP5
B	GLY6
C	GLY3
C	GLY6
C	GLN23
C	HOH209
C	HOH220
C	HOH230

---

site_id	AD9
Number of Residues	11
Details	binding site for Di-peptide HYP C 5 and GLY C 6

Chain	Residue
A	PRO4
A	HYP5
A	GLY6
B	GLY6
B	PRO7
C	PRO4
C	PRO7
C	HOH209
C	HOH220
C	HOH221
C	HOH230

---

site_id	AE1
Number of Residues	11
Details	binding site for Di-peptide PRO C 10 and HYP C 11

Chain	Residue
A	GLY9
A	PRO10
A	GLN23
B	HYP11
B	GLY12
B	HOH213
C	GLY9
C	GLY12
C	HOH210
C	HOH216
C	HOH227

---

site_id	AE2
Number of Residues	12
Details	binding site for Di-peptide HYP C 11 and GLY C 12

Chain	Residue
A	PRO10
A	GLY12
A	GLN23
B	GLY12
B	LEU13
B	HOH213
C	PRO10
C	LEU13
C	HOH210
C	HOH216
C	HOH227
C	HOH233

---

site_id	AE3
Number of Residues	11
Details	binding site for Di-peptide PRO C 31 and HYP C 32

Chain	Residue
A	GLN23
A	GLY30
A	PRO31
A	HOH214
A	HOH232
B	HYP5
B	GLY30
B	HYP32
B	GLY33
C	GLY30
C	GLY33

---

site_id	AE4
Number of Residues	11
Details	binding site for Di-peptide HYP C 32 and GLY C 33

Chain	Residue
A	GLN23
A	PRO31
A	GLY33
A	HOH214
A	HOH232
B	HYP5
B	GLY33
B	PRO34
C	PRO31
C	PRO34
C	HOH211

---

site_id	AE5
Number of Residues	13
Details	binding site for Di-peptide PRO C 34 and HYP C 35

Chain	Residue
A	GLY33
A	PRO34
B	HYP2
B	GLN23
B	GLY33
B	HYP35
B	GLY36
B	HOH211
C	GLY33
C	GLY36
C	NH237
C	HOH222
C	HOH225

---

site_id	AE6
Number of Residues	11
Details	binding site for Di-peptide HYP C 35 and GLY C 36

Chain	Residue
A	ARG17
A	PRO34
A	HYP35
B	HYP2
B	GLY36
B	HOH211
B	HOH224
C	PRO34
C	NH237
C	HOH222
C	HOH225

---

site_id	AE7
Number of Residues	8
Details	binding site for Di-peptide GLY C 36 and NH2 C 37

Chain	Residue
A	ARG17
A	PRO34
A	HYP35
A	GLY36
B	GLY36
B	HOH224
C	PRO34
C	HYP35

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"5-hydroxylysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Glycosylation: {"description":"O-linked (Gal...) hydroxylysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---