Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue CHO A 601 |
| Chain | Residue |
| A | TRP245 |
| B | ARG390 |
| B | VAL391 |
| B | ARG392 |
| B | HOH781 |
| A | ALA247 |
| A | TYR250 |
| A | TYR435 |
| A | MET436 |
| A | ARG437 |
| A | HOH740 |
| B | GLN312 |
| B | GLY314 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | LEU258 |
| A | ASP403 |
| A | ARG433 |
| A | ALA448 |
| A | ILE449 |
| A | ASP450 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | PRO262 |
| A | GLN263 |
| A | TRP264 |
| A | ASP403 |
| A | ILE405 |
| A | HOH702 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | TYR295 |
| A | GLN340 |
| A | THR341 |
| A | GLU342 |
| A | VAL387 |
| A | ARG390 |
| A | VAL391 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | PRO280 |
| A | VAL281 |
| A | SER282 |
| A | TRP285 |
| A | LEU326 |
| A | HOH756 |
| B | LEU239 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 606 |
| Chain | Residue |
| A | ASN364 |
| A | ASP366 |
| E | LYS94 |
| E | GLY96 |
| E | ASP98 |
| E | HOH316 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue CHO B 600 |
| Chain | Residue |
| A | GLN312 |
| A | GLY314 |
| A | ARG390 |
| A | VAL391 |
| A | ARG392 |
| A | HOH733 |
| A | HOH761 |
| B | TRP245 |
| B | ALA247 |
| B | TYR435 |
| B | MET436 |
| B | ARG437 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 601 |
| Chain | Residue |
| B | GLN438 |
| B | ASP440 |
| B | GLU447 |
| B | HOH769 |
| B | HOH800 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | ASP403 |
| B | ALA448 |
| B | ILE449 |
| B | ASP450 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | PRO262 |
| B | GLN263 |
| B | TRP264 |
| B | ASP403 |
| B | HOH758 |
| B | HOH759 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | TYR295 |
| B | GLN340 |
| B | THR341 |
| B | GLU342 |
| B | VAL387 |
| B | ARG390 |
| B | VAL391 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| A | LEU239 |
| B | PRO280 |
| B | VAL281 |
| B | SER282 |
| B | TRP285 |
| B | LEU326 |
| B | HOH742 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue CHO C 601 |
| Chain | Residue |
| C | TRP245 |
| C | ALA247 |
| C | TYR250 |
| C | TYR435 |
| C | MET436 |
| C | ARG437 |
| D | GLN312 |
| D | GLY314 |
| D | GLN340 |
| D | ARG390 |
| D | VAL391 |
| D | ARG392 |
| D | HOH759 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 602 |
| Chain | Residue |
| C | PRO262 |
| C | GLN263 |
| C | TRP264 |
| C | ASP403 |
| C | HOH724 |
| C | HOH769 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 603 |
| Chain | Residue |
| C | ASP403 |
| C | ARG433 |
| C | ALA448 |
| C | ILE449 |
| C | ASP450 |
| C | HOH805 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 604 |
| Chain | Residue |
| C | TYR295 |
| C | GLN340 |
| C | THR341 |
| C | GLU342 |
| C | VAL387 |
| C | GLY389 |
| C | ARG390 |
| C | VAL391 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 605 |
| Chain | Residue |
| C | ASN364 |
| C | ASP366 |
| C | HOH811 |
| F | LYS94 |
| F | GLY96 |
| F | ASP98 |
| site_id | AD9 |
| Number of Residues | 13 |
| Details | binding site for residue CHO D 600 |
| Chain | Residue |
| C | ILE310 |
| C | GLN312 |
| C | GLY314 |
| C | ARG390 |
| C | VAL391 |
| C | ARG392 |
| C | HOH710 |
| D | TRP245 |
| D | ALA247 |
| D | TYR250 |
| D | TYR435 |
| D | ARG437 |
| D | HOH715 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 601 |
| Chain | Residue |
| D | GLN438 |
| D | ASP440 |
| D | GLU447 |
| D | HOH707 |
| D | HOH764 |
| D | HOH769 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 602 |
| Chain | Residue |
| D | PRO262 |
| D | GLN263 |
| D | TRP264 |
| D | ASP403 |
| D | HOH712 |
| D | HOH750 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 603 |
| Chain | Residue |
| D | ASP403 |
| D | ALA448 |
| D | ILE449 |
| D | ASP450 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 201 |
| Chain | Residue |
| E | GLY12 |
| E | GLN13 |
| E | GLY16 |
| E | SER17 |
| E | LEU80 |
| E | HOH302 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG E 202 |
| Chain | Residue |
| E | LYS32 |
| E | GLU49 |
| E | THR50 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 201 |
| Chain | Residue |
| F | GLY12 |
| F | GLN13 |
| F | GLY16 |
| F | SER17 |
| F | HOH313 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue PGE F 202 |
| Chain | Residue |
| F | LYS32 |
| F | GLU49 |
| F | THR50 |
