Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 0016579 | biological_process | protein deubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 801 |
| Chain | Residue |
| A | ARG210 |
| A | LYS262 |
| A | TRP266 |
| C | GLU51 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide AYE A 802 and GLY C 75 |
| Chain | Residue |
| A | GLY599 |
| A | HIS600 |
| C | LEU73 |
| C | ARG74 |
| A | ASN166 |
| A | CYS171 |
| A | TRP172 |
| A | GLN253 |
| A | GLN254 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide AYE B 801 and GLY D 75 |
| Chain | Residue |
| B | ASN169 |
| B | CYS171 |
| B | TRP172 |
| B | GLN253 |
| B | GLN254 |
| B | GLY599 |
| B | TYR601 |
| D | LEU73 |
| D | ARG74 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| C | LYS27-ASP52 | |
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLknvGNtCWFSAvIQ |
| Chain | Residue | Details |
| A | GLY163-GLN178 | |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YrLhAVlvHdGqana..GHY |
| Chain | Residue | Details |
| A | TYR584-TYR601 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q5I043","evidenceCode":"ECO:0000250"}]} |
