6H2A

Structure of S70A BlaC from Mycobacterium tuberculosis obtained from crystals produced in the presence of DTT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030655	biological_process	beta-lactam antibiotic catabolic process
B	0046677	biological_process	response to antibiotic
C	0008800	molecular_function	beta-lactamase activity
C	0017001	biological_process	antibiotic catabolic process
C	0030655	biological_process	beta-lactam antibiotic catabolic process
C	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue DTT A 502

Chain	Residue
A	ASP42
A	ARG267
A	GLU275
A	ARG277
B	ARG65
B	GLU179

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site_id	AC2
Number of Residues	4
Details	binding site for residue PO4 A 503

Chain	Residue
B	ASP42
A	ARG173
A	ASP241
A	PO4504

---

site_id	AC3
Number of Residues	6
Details	binding site for residue PO4 A 504

Chain	Residue
A	SER102
A	ILE103
A	PRO169
A	ASN172
A	TAM501
A	PO4503

---

site_id	AC4
Number of Residues	3
Details	binding site for residue TAM A 506

Chain	Residue
A	THR87
A	HIS88
A	LYS91

---

site_id	AC5
Number of Residues	6
Details	binding site for residue GOL A 507

Chain	Residue
A	ARG44
A	ARG65
A	PHE66
A	ALA67
A	ARG244
A	ASP266

---

site_id	AC6
Number of Residues	7
Details	binding site for residue DTT B 401

Chain	Residue
B	ALA70
B	LYS73
B	SER128
B	GLU168
B	ASN172
B	THR237
B	THR239

---

site_id	AC7
Number of Residues	3
Details	binding site for residue DTT B 402

Chain	Residue
B	ARG163
B	ASP165
B	ARG180

---

site_id	AC8
Number of Residues	3
Details	binding site for residue PO4 B 403

Chain	Residue
B	ASP122
B	ARG126
B	ARG215

---

site_id	AC9
Number of Residues	4
Details	binding site for residue PO4 B 404

Chain	Residue
B	ASP99
B	ARG101
B	ASN134
B	GLU167

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GOL B 405

Chain	Residue
B	GLY144

---

site_id	AD2
Number of Residues	2
Details	binding site for residue GOL B 406

Chain	Residue
B	GLU59
B	ASP63

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site_id	AD3
Number of Residues	6
Details	binding site for residue DTT C 401

Chain	Residue
C	ALA70
C	LYS73
C	GLU168
C	LYS236
C	THR237
C	THR239

---

site_id	AD4
Number of Residues	4
Details	binding site for residue PO4 C 402

Chain	Residue
C	ALA214
C	ARG224
C	LYS232
C	VAL233

---

site_id	AD5
Number of Residues	2
Details	binding site for residue GOL C 403

Chain	Residue
C	ARG267
C	GLU275

---

site_id	AD6
Number of Residues	11
Details	binding site for residues TAM A 501 and PO4 A 505

Chain	Residue
A	CYS69
A	ALA70
A	LYS73
A	SER128
A	GLU168
A	ASN172
A	THR218
A	THR237
A	GLY238
A	THR239
A	PO4504

---

site_id	AD7
Number of Residues	11
Details	binding site for residues TAM A 501 and PO4 A 505

Chain	Residue
A	CYS69
A	ALA70
A	LYS73
A	SER128
A	GLU168
A	ASN172
A	THR218
A	THR237
A	GLY238
A	THR239
A	PO4504

---

site_id	AD8
Number of Residues	11
Details	binding site for residues TAM A 501 and PO4 A 505

Chain	Residue
A	CYS69
A	ALA70
A	LYS73
A	SER128
A	GLU168
A	ASN172
A	THR218
A	THR237
A	GLY238
A	THR239
A	PO4504

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