6GX7

Tubulin-CopN-alphaRep complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005525	molecular_function	GTP binding
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0005879	cellular_component	axonemal microtubule
A	0005929	cellular_component	cilium
A	0007010	biological_process	cytoskeleton organization
A	0007017	biological_process	microtubule-based process
A	0015630	cellular_component	microtubule cytoskeleton
A	0030317	biological_process	flagellated sperm motility
A	0036126	cellular_component	sperm flagellum
A	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
A	0042802	molecular_function	identical protein binding
A	0055037	cellular_component	recycling endosome
B	0003924	molecular_function	GTPase activity
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005525	molecular_function	GTP binding
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0007010	biological_process	cytoskeleton organization
B	0007017	biological_process	microtubule-based process
C	0005200	molecular_function	structural constituent of cytoskeleton
C	0005525	molecular_function	GTP binding
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0005879	cellular_component	axonemal microtubule
C	0005929	cellular_component	cilium
C	0007010	biological_process	cytoskeleton organization
C	0007017	biological_process	microtubule-based process
C	0015630	cellular_component	microtubule cytoskeleton
C	0030317	biological_process	flagellated sperm motility
C	0036126	cellular_component	sperm flagellum
C	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
C	0042802	molecular_function	identical protein binding
C	0055037	cellular_component	recycling endosome
D	0003924	molecular_function	GTPase activity
D	0005200	molecular_function	structural constituent of cytoskeleton
D	0005525	molecular_function	GTP binding
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0007010	biological_process	cytoskeleton organization
D	0007017	biological_process	microtubule-based process
G	0009986	cellular_component	cell surface
G	0019867	cellular_component	outer membrane
G	0030254	biological_process	protein secretion by the type III secretion system
G	0046903	biological_process	secretion
G	0050709	biological_process	negative regulation of protein secretion
H	0009986	cellular_component	cell surface
H	0019867	cellular_component	outer membrane
H	0030254	biological_process	protein secretion by the type III secretion system
H	0046903	biological_process	secretion
H	0050709	biological_process	negative regulation of protein secretion

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	binding site for residue GTP A 501

Chain	Residue
A	GLY10
A	GLY143
A	GLY144
A	THR145
A	GLY146
A	ILE171
A	VAL177
A	GLU183
A	ASN206
A	TYR224
A	ASN228
A	GLN11
A	ILE231
A	MG502
A	ALA12
A	GLN15
A	ASP69
A	ASP98
A	ALA99
A	ASN101
A	SER140

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MG A 502

Chain	Residue
A	GLU71
A	GTP501

---

site_id	AC3
Number of Residues	1
Details	binding site for residue SO4 A 503

Chain	Residue
A	TYR224

---

site_id	AC4
Number of Residues	21
Details	binding site for residue GTP B 501

Chain	Residue
B	GLY10
B	GLN11
B	CYS12
B	GLN15
B	GLY98
B	ALA99
B	GLY100
B	ASN101
B	SER140
B	GLY143
B	GLY144
B	THR145
B	GLY146
B	PRO173
B	VAL177
B	SER178
B	GLU183
B	ASN206
B	TYR224
B	ASN228
B	MG502

---

site_id	AC5
Number of Residues	3
Details	binding site for residue MG B 502

Chain	Residue
B	GLN11
B	ASP69
B	GTP501

---

site_id	AC6
Number of Residues	7
Details	binding site for residue MES B 503

Chain	Residue
B	ARG158
B	PRO162
B	ASP163
B	ARG164
B	ASN197
B	ASP199
B	ARG253

---

site_id	AC7
Number of Residues	7
Details	binding site for residue MES B 504

Chain	Residue
B	ASP297
B	SER298
B	PRO307
B	ARG308
B	ASN339
B	TYR342
B	PHE343

---

site_id	AC8
Number of Residues	3
Details	binding site for residue GOL B 505

Chain	Residue
B	VAL177
B	PRO222
B	TYR224

---

site_id	AC9
Number of Residues	22
Details	binding site for residue GTP C 501

Chain	Residue
C	GLY10
C	GLN11
C	ALA12
C	GLN15
C	GLU71
C	ASP98
C	ALA99
C	ASN101
C	SER140
C	GLY143
C	GLY144
C	THR145
C	GLY146
C	VAL177
C	THR179
C	GLU183
C	ASN206
C	TYR224
C	ASN228
C	ILE231
C	MG502
D	LYS254

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MG C 502

Chain	Residue
C	GLU71
C	GTP501

---

site_id	AD2
Number of Residues	1
Details	binding site for residue SO4 C 503

Chain	Residue
C	TYR224

---

site_id	AD3
Number of Residues	20
Details	binding site for residue GTP D 501

Chain	Residue
D	GLY144
D	THR145
D	GLY146
D	PRO173
D	VAL177
D	SER178
D	GLU183
D	ASN206
D	TYR224
D	ASN228
D	MG502
D	GLY10
D	GLN11
D	CYS12
D	GLY98
D	ALA99
D	GLY100
D	ASN101
D	SER140
D	GLY143

---

site_id	AD4
Number of Residues	3
Details	binding site for residue MG D 502

Chain	Residue
D	GLN11
D	ASP69
D	GTP501

---

site_id	AD5
Number of Residues	7
Details	binding site for residue MES D 503

Chain	Residue
D	ARG158
D	PRO162
D	ASP163
D	ARG164
D	ASN197
D	ASP199
D	ARG253

---

site_id	AD6
Number of Residues	8
Details	binding site for residue MES D 504

Chain	Residue
D	PHE296
D	ASP297
D	SER298
D	ASP306
D	PRO307
D	ARG308
D	ASN339
D	TYR342

---

site_id	AD7
Number of Residues	4
Details	binding site for residue PGE D 505

Chain	Residue
D	TYR108
D	GLY412
D	GLU417
D	GLU420

---

site_id	AD8
Number of Residues	3
Details	binding site for residue GOL D 506

Chain	Residue
D	VAL177
D	PRO222
D	TYR224

---

site_id	AD9
Number of Residues	4
Details	binding site for residue GOL D 507

Chain	Residue
D	LYS338
D	ASN339
D	SER340
D	SER341

---

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
B	GLY142-GLY148
A	GLY142-GLY148

---

site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
B	MET1-ILE4

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