Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | ARG161 |
| A | ASP162 |
| A | VAL163 |
| A | THR212 |
| A | MET216 |
| A | ALA234 |
| A | HOH581 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | TYR152 |
| A | HOH790 |
| A | ASN66 |
| A | SER148 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 403 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | SER208 |
| A | THR210 |
| A | THR220 |
| A | GLN226 |
| A | HOH560 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | PHE43 |
| A | ASN62 |
| A | THR65 |
| A | GLU67 |
| A | VAL69 |
| A | TYR103 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue F92 A 406 |
| Chain | Residue |
| A | LEU57 |
| A | ALA70 |
| A | LYS72 |
| A | MET114 |
| A | LEU116 |
| A | GLU117 |
| A | LEU118 |
| A | LEU119 |
| A | ASP125 |
| A | GLU166 |
| A | ILE184 |
| A | HOH511 |
| A | HOH580 |
| A | HOH594 |
| A | HOH612 |
| A | HOH737 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGCGNFGELRlGknlytney..........VAIK |
| Chain | Residue | Details |
| A | ILE49-LYS72 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LiYrDVKpeNFLI |
| Chain | Residue | Details |
| A | LEU158-ILE170 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 270 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
