6GL7

Neurturin-GFRa2-RET extracellular complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008083	molecular_function	growth factor activity
A	0030116	molecular_function	glial cell-derived neurotrophic factor receptor binding
A	0030971	molecular_function	receptor tyrosine kinase binding
B	0008083	molecular_function	growth factor activity
B	0030116	molecular_function	glial cell-derived neurotrophic factor receptor binding
B	0030971	molecular_function	receptor tyrosine kinase binding
C	0005886	cellular_component	plasma membrane
C	0007169	biological_process	cell surface receptor protein tyrosine kinase signaling pathway
C	0007399	biological_process	nervous system development
C	0009897	cellular_component	external side of plasma membrane
C	0016167	molecular_function	glial cell-derived neurotrophic factor receptor activity
C	0019898	cellular_component	extrinsic component of membrane
C	0035860	biological_process	glial cell-derived neurotrophic factor receptor signaling pathway
C	0038023	molecular_function	signaling receptor activity
C	0043235	cellular_component	receptor complex
C	0098552	cellular_component	side of membrane
C	1904399	molecular_function	heparan sulfate binding
D	0005886	cellular_component	plasma membrane
D	0007169	biological_process	cell surface receptor protein tyrosine kinase signaling pathway
D	0007399	biological_process	nervous system development
D	0009897	cellular_component	external side of plasma membrane
D	0016167	molecular_function	glial cell-derived neurotrophic factor receptor activity
D	0019898	cellular_component	extrinsic component of membrane
D	0035860	biological_process	glial cell-derived neurotrophic factor receptor signaling pathway
D	0038023	molecular_function	signaling receptor activity
D	0043235	cellular_component	receptor complex
D	0098552	cellular_component	side of membrane
D	1904399	molecular_function	heparan sulfate binding
E	0005509	molecular_function	calcium ion binding
E	0007156	biological_process	homophilic cell-cell adhesion
E	0016020	cellular_component	membrane
F	0005509	molecular_function	calcium ion binding
F	0007156	biological_process	homophilic cell-cell adhesion
F	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29414779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31535977","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25242331","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4UX8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6Q2J","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31535977","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Q2J","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20473317","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---