6GHL
cyanobacterial GAPDH with full-length CP12
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006006 | biological_process | glucose metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050661 | molecular_function | NADP binding |
| C | 0051287 | molecular_function | NAD binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006006 | biological_process | glucose metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0050661 | molecular_function | NADP binding |
| D | 0051287 | molecular_function | NAD binding |
| E | 0080153 | biological_process | negative regulation of reductive pentose-phosphate cycle |
| F | 0080153 | biological_process | negative regulation of reductive pentose-phosphate cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue NAD A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | THR100 |
| A | GLY101 |
| A | THR123 |
| A | ALA124 |
| A | CYS154 |
| A | ASN317 |
| A | TYR321 |
| A | HOH1107 |
| A | HOH1117 |
| A | HOH1119 |
| A | PHE9 |
| A | HOH1129 |
| D | HOH1117 |
| E | GLU69 |
| F | HIS45 |
| A | GLY10 |
| A | ARG11 |
| A | ILE12 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| A | ALA99 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue NAD B 1001 |
| Chain | Residue |
| B | GLY8 |
| B | PHE9 |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ASP80 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | THR123 |
| B | ALA124 |
| B | CYS154 |
| B | THR184 |
| B | ASN317 |
| B | GLU318 |
| B | TYR321 |
| B | HOH1112 |
| B | HOH1118 |
| B | HOH1120 |
| C | HOH1110 |
| F | ASP66 |
| F | TYR73 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue NAD C 1001 |
| Chain | Residue |
| C | GLY8 |
| C | PHE9 |
| C | GLY10 |
| C | ARG11 |
| C | ILE12 |
| C | ASN35 |
| C | ASP36 |
| C | THR37 |
| C | ARG81 |
| C | ALA99 |
| C | THR100 |
| C | GLY101 |
| C | THR123 |
| C | ALA124 |
| C | CYS154 |
| C | ASN317 |
| C | TYR321 |
| C | HOH1129 |
| C | HOH1130 |
| C | HOH1138 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue MLI C 1002 |
| Chain | Residue |
| C | SER153 |
| C | CYS154 |
| C | THR155 |
| C | ARG199 |
| C | THR212 |
| C | GLY213 |
| C | ARG235 |
| C | HOH1141 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | binding site for residue NAD D 1001 |
| Chain | Residue |
| E | TYR73 |
| D | GLY8 |
| D | PHE9 |
| D | GLY10 |
| D | ARG11 |
| D | ILE12 |
| D | ASN35 |
| D | ASP36 |
| D | THR37 |
| D | ARG81 |
| D | ALA99 |
| D | GLY101 |
| D | THR123 |
| D | ALA124 |
| D | CYS154 |
| D | THR184 |
| D | ASN317 |
| D | TYR321 |
| D | HOH1102 |
| D | HOH1106 |
| D | HOH1110 |
| D | HOH1111 |
| E | ASP66 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA152-LEU159 |
