Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue EYQ A 1201 |
| Chain | Residue |
| A | LEU881 |
| A | GLU966 |
| A | ASP1003 |
| A | ARG1007 |
| A | ASN1008 |
| A | LEU1010 |
| A | GLY1020 |
| A | ASP1021 |
| A | HOH1344 |
| A | HOH1358 |
| A | HOH1381 |
| A | GLY882 |
| A | HOH1412 |
| A | VAL889 |
| A | ALA906 |
| A | GLU957 |
| A | PHE958 |
| A | LEU959 |
| A | PRO960 |
| A | GLY962 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue EYQ B 1201 |
| Chain | Residue |
| B | LEU881 |
| B | GLY882 |
| B | ALA906 |
| B | GLU957 |
| B | PHE958 |
| B | LEU959 |
| B | PRO960 |
| B | GLY962 |
| B | GLU966 |
| B | ASP1003 |
| B | ARG1007 |
| B | ASN1008 |
| B | LEU1010 |
| B | GLY1020 |
| B | ASP1021 |
| B | ASP1042 |
| B | HOH1316 |
| B | HOH1362 |
| B | HOH1430 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGHFGKVElCrydpegdntgeq......VAVK |
| Chain | Residue | Details |
| A | LEU881-LYS908 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLAARNVLV |
| Chain | Residue | Details |
| A | TYR999-VAL1011 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32750333","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"11909529","evidenceCode":"ECO:0000269"}]} |
