6GG8
Mineralocorticoid receptor in complex with (s)-13
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 1101 |
| Chain | Residue |
| A | GLU746 |
| A | PRO747 |
| A | VAL780 |
| A | TRP783 |
| A | ALA813 |
| A | LYS873 |
| A | HOH1261 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue EY8 A 1102 |
| Chain | Residue |
| A | ALA773 |
| A | GLN776 |
| A | MET807 |
| A | SER810 |
| A | SER811 |
| A | LEU814 |
| A | ARG817 |
| A | PHE829 |
| A | MET845 |
| A | CYS849 |
| A | PHE941 |
| A | CYS942 |
| A | THR945 |
| A | VAL954 |
| A | ASN770 |
| A | LEU772 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for coactivator binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15908963","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YA3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 7"} |
| Chain | Residue | Details |
