6GG6

Crystal structure of M2 PYK in complex with Serine.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0003824	molecular_function	catalytic activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004713	molecular_function	protein tyrosine kinase activity
A	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
A	0004743	molecular_function	pyruvate kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005791	cellular_component	rough endoplasmic reticulum
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006096	biological_process	glycolytic process
A	0006417	biological_process	regulation of translation
A	0012501	biological_process	programmed cell death
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0023026	molecular_function	MHC class II protein complex binding
A	0030955	molecular_function	potassium ion binding
A	0031982	cellular_component	vesicle
A	0032869	biological_process	cellular response to insulin stimulus
A	0034774	cellular_component	secretory granule lumen
A	0045296	molecular_function	cadherin binding
A	0046872	molecular_function	metal ion binding
A	0061621	biological_process	canonical glycolysis
A	0070062	cellular_component	extracellular exosome
A	1903561	cellular_component	extracellular vesicle
A	1903672	biological_process	positive regulation of sprouting angiogenesis
A	1904813	cellular_component	ficolin-1-rich granule lumen
A	2000767	biological_process	positive regulation of cytoplasmic translation
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0003824	molecular_function	catalytic activity
B	0004674	molecular_function	protein serine/threonine kinase activity
B	0004713	molecular_function	protein tyrosine kinase activity
B	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
B	0004743	molecular_function	pyruvate kinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005791	cellular_component	rough endoplasmic reticulum
B	0005829	cellular_component	cytosol
B	0005929	cellular_component	cilium
B	0006096	biological_process	glycolytic process
B	0006417	biological_process	regulation of translation
B	0012501	biological_process	programmed cell death
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0023026	molecular_function	MHC class II protein complex binding
B	0030955	molecular_function	potassium ion binding
B	0031982	cellular_component	vesicle
B	0032869	biological_process	cellular response to insulin stimulus
B	0034774	cellular_component	secretory granule lumen
B	0045296	molecular_function	cadherin binding
B	0046872	molecular_function	metal ion binding
B	0061621	biological_process	canonical glycolysis
B	0070062	cellular_component	extracellular exosome
B	1903561	cellular_component	extracellular vesicle
B	1903672	biological_process	positive regulation of sprouting angiogenesis
B	1904813	cellular_component	ficolin-1-rich granule lumen
B	2000767	biological_process	positive regulation of cytoplasmic translation
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0003824	molecular_function	catalytic activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0004713	molecular_function	protein tyrosine kinase activity
C	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
C	0004743	molecular_function	pyruvate kinase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005791	cellular_component	rough endoplasmic reticulum
C	0005829	cellular_component	cytosol
C	0005929	cellular_component	cilium
C	0006096	biological_process	glycolytic process
C	0006417	biological_process	regulation of translation
C	0012501	biological_process	programmed cell death
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0023026	molecular_function	MHC class II protein complex binding
C	0030955	molecular_function	potassium ion binding
C	0031982	cellular_component	vesicle
C	0032869	biological_process	cellular response to insulin stimulus
C	0034774	cellular_component	secretory granule lumen
C	0045296	molecular_function	cadherin binding
C	0046872	molecular_function	metal ion binding
C	0061621	biological_process	canonical glycolysis
C	0070062	cellular_component	extracellular exosome
C	1903561	cellular_component	extracellular vesicle
C	1903672	biological_process	positive regulation of sprouting angiogenesis
C	1904813	cellular_component	ficolin-1-rich granule lumen
C	2000767	biological_process	positive regulation of cytoplasmic translation
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0003824	molecular_function	catalytic activity
D	0004674	molecular_function	protein serine/threonine kinase activity
D	0004713	molecular_function	protein tyrosine kinase activity
D	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
D	0004743	molecular_function	pyruvate kinase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005791	cellular_component	rough endoplasmic reticulum
D	0005829	cellular_component	cytosol
D	0005929	cellular_component	cilium
D	0006096	biological_process	glycolytic process
D	0006417	biological_process	regulation of translation
D	0012501	biological_process	programmed cell death
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0023026	molecular_function	MHC class II protein complex binding
D	0030955	molecular_function	potassium ion binding
D	0031982	cellular_component	vesicle
D	0032869	biological_process	cellular response to insulin stimulus
D	0034774	cellular_component	secretory granule lumen
D	0045296	molecular_function	cadherin binding
D	0046872	molecular_function	metal ion binding
D	0061621	biological_process	canonical glycolysis
D	0070062	cellular_component	extracellular exosome
D	1903561	cellular_component	extracellular vesicle
D	1903672	biological_process	positive regulation of sprouting angiogenesis
D	1904813	cellular_component	ficolin-1-rich granule lumen
D	2000767	biological_process	positive regulation of cytoplasmic translation
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0003723	molecular_function	RNA binding
E	0003729	molecular_function	mRNA binding
E	0003824	molecular_function	catalytic activity
E	0004674	molecular_function	protein serine/threonine kinase activity
E	0004713	molecular_function	protein tyrosine kinase activity
E	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
E	0004743	molecular_function	pyruvate kinase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005791	cellular_component	rough endoplasmic reticulum
E	0005829	cellular_component	cytosol
E	0005929	cellular_component	cilium
E	0006096	biological_process	glycolytic process
E	0006417	biological_process	regulation of translation
E	0012501	biological_process	programmed cell death
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0023026	molecular_function	MHC class II protein complex binding
E	0030955	molecular_function	potassium ion binding
E	0031982	cellular_component	vesicle
E	0032869	biological_process	cellular response to insulin stimulus
E	0034774	cellular_component	secretory granule lumen
E	0045296	molecular_function	cadherin binding
E	0046872	molecular_function	metal ion binding
E	0061621	biological_process	canonical glycolysis
E	0070062	cellular_component	extracellular exosome
E	1903561	cellular_component	extracellular vesicle
E	1903672	biological_process	positive regulation of sprouting angiogenesis
E	1904813	cellular_component	ficolin-1-rich granule lumen
E	2000767	biological_process	positive regulation of cytoplasmic translation
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003824	molecular_function	catalytic activity
F	0004674	molecular_function	protein serine/threonine kinase activity
F	0004713	molecular_function	protein tyrosine kinase activity
F	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
F	0004743	molecular_function	pyruvate kinase activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005791	cellular_component	rough endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0005929	cellular_component	cilium
F	0006096	biological_process	glycolytic process
F	0006417	biological_process	regulation of translation
F	0012501	biological_process	programmed cell death
F	0016301	molecular_function	kinase activity
F	0016740	molecular_function	transferase activity
F	0023026	molecular_function	MHC class II protein complex binding
F	0030955	molecular_function	potassium ion binding
F	0031982	cellular_component	vesicle
F	0032869	biological_process	cellular response to insulin stimulus
F	0034774	cellular_component	secretory granule lumen
F	0045296	molecular_function	cadherin binding
F	0046872	molecular_function	metal ion binding
F	0061621	biological_process	canonical glycolysis
F	0070062	cellular_component	extracellular exosome
F	1903561	cellular_component	extracellular vesicle
F	1903672	biological_process	positive regulation of sprouting angiogenesis
F	1904813	cellular_component	ficolin-1-rich granule lumen
F	2000767	biological_process	positive regulation of cytoplasmic translation
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003824	molecular_function	catalytic activity
G	0004674	molecular_function	protein serine/threonine kinase activity
G	0004713	molecular_function	protein tyrosine kinase activity
G	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
G	0004743	molecular_function	pyruvate kinase activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005791	cellular_component	rough endoplasmic reticulum
G	0005829	cellular_component	cytosol
G	0005929	cellular_component	cilium
G	0006096	biological_process	glycolytic process
G	0006417	biological_process	regulation of translation
G	0012501	biological_process	programmed cell death
G	0016301	molecular_function	kinase activity
G	0016740	molecular_function	transferase activity
G	0023026	molecular_function	MHC class II protein complex binding
G	0030955	molecular_function	potassium ion binding
G	0031982	cellular_component	vesicle
G	0032869	biological_process	cellular response to insulin stimulus
G	0034774	cellular_component	secretory granule lumen
G	0045296	molecular_function	cadherin binding
G	0046872	molecular_function	metal ion binding
G	0061621	biological_process	canonical glycolysis
G	0070062	cellular_component	extracellular exosome
G	1903561	cellular_component	extracellular vesicle
G	1903672	biological_process	positive regulation of sprouting angiogenesis
G	1904813	cellular_component	ficolin-1-rich granule lumen
G	2000767	biological_process	positive regulation of cytoplasmic translation
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0003824	molecular_function	catalytic activity
H	0004674	molecular_function	protein serine/threonine kinase activity
H	0004713	molecular_function	protein tyrosine kinase activity
H	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
H	0004743	molecular_function	pyruvate kinase activity
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005791	cellular_component	rough endoplasmic reticulum
H	0005829	cellular_component	cytosol
H	0005929	cellular_component	cilium
H	0006096	biological_process	glycolytic process
H	0006417	biological_process	regulation of translation
H	0012501	biological_process	programmed cell death
H	0016301	molecular_function	kinase activity
H	0016740	molecular_function	transferase activity
H	0023026	molecular_function	MHC class II protein complex binding
H	0030955	molecular_function	potassium ion binding
H	0031982	cellular_component	vesicle
H	0032869	biological_process	cellular response to insulin stimulus
H	0034774	cellular_component	secretory granule lumen
H	0045296	molecular_function	cadherin binding
H	0046872	molecular_function	metal ion binding
H	0061621	biological_process	canonical glycolysis
H	0070062	cellular_component	extracellular exosome
H	1903561	cellular_component	extracellular vesicle
H	1903672	biological_process	positive regulation of sprouting angiogenesis
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	2000767	biological_process	positive regulation of cytoplasmic translation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue K A 601

Chain	Residue
A	ASN75
A	SER77
A	ASP113
A	THR114
A	GLU118

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 602

Chain	Residue
A	LYS270
A	GLU272
A	ASP296

---

site_id	AC3
Number of Residues	8
Details	binding site for residue SER A 603

Chain	Residue
A	ASN44
A	ASN70
A	ARG106
A	HIS464
A	ILE469
A	PHE470
A	PRO471
A	ARG43

---

site_id	AC4
Number of Residues	8
Details	binding site for residue PO4 A 604

Chain	Residue
A	THR432
A	LYS433
A	SER434
A	ARG436
A	SER437
A	SER519
A	GLY520
A	THR522

---

site_id	AC5
Number of Residues	6
Details	binding site for residue K B 601

Chain	Residue
B	ASN75
B	SER77
B	ASP113
B	THR114
B	GLU118
B	SER243

---

site_id	AC6
Number of Residues	4
Details	binding site for residue MG B 602

Chain	Residue
B	LYS270
B	GLU272
B	ALA293
B	ASP296

---

site_id	AC7
Number of Residues	9
Details	binding site for residue SER B 603

Chain	Residue
B	ARG43
B	ASN44
B	GLY46
B	ASN70
B	ARG106
B	HIS464
B	ILE469
B	PHE470
B	PRO471

---

site_id	AC8
Number of Residues	8
Details	binding site for residue PO4 B 604

Chain	Residue
B	THR432
B	LYS433
B	SER434
B	ARG436
B	SER437
B	SER519
B	GLY520
B	THR522

---

site_id	AC9
Number of Residues	6
Details	binding site for residue K C 601

Chain	Residue
C	ASN75
C	SER77
C	ASP113
C	THR114
C	GLU118
C	SER243

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MG C 602

Chain	Residue
C	GLU272
C	ASP296

---

site_id	AD2
Number of Residues	8
Details	binding site for residue SER C 603

Chain	Residue
C	ARG43
C	ASN44
C	ASN70
C	ARG106
C	HIS464
C	ILE469
C	PHE470
C	PRO471

---

site_id	AD3
Number of Residues	8
Details	binding site for residue PO4 C 604

Chain	Residue
C	THR432
C	LYS433
C	SER434
C	ARG436
C	SER437
C	SER519
C	GLY520
C	THR522

---

site_id	AD4
Number of Residues	6
Details	binding site for residue K D 601

Chain	Residue
D	ASN75
D	SER77
D	ASP113
D	THR114
D	GLU118
D	SER243

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG D 602

Chain	Residue
D	LYS270
D	GLU272
D	ASP296

---

site_id	AD6
Number of Residues	8
Details	binding site for residue SER D 603

Chain	Residue
D	ARG43
D	ASN44
D	ASN70
D	ARG106
D	HIS464
D	ILE469
D	PHE470
D	PRO471

---

site_id	AD7
Number of Residues	8
Details	binding site for residue PO4 D 604

Chain	Residue
D	THR522
D	THR432
D	LYS433
D	SER434
D	ARG436
D	SER437
D	SER519
D	GLY520

---

site_id	AD8
Number of Residues	6
Details	binding site for residue K E 601

Chain	Residue
E	ASN75
E	SER77
E	ASP113
E	THR114
E	GLU118
E	SER243

---

site_id	AD9
Number of Residues	3
Details	binding site for residue MG E 602

Chain	Residue
E	LYS270
E	GLU272
E	ASP296

---

site_id	AE1
Number of Residues	8
Details	binding site for residue SER E 603

Chain	Residue
E	ARG43
E	ASN44
E	ASN70
E	ARG106
E	HIS464
E	ILE469
E	PHE470
E	PRO471

---

site_id	AE2
Number of Residues	8
Details	binding site for residue PO4 E 604

Chain	Residue
E	THR432
E	LYS433
E	SER434
E	ARG436
E	SER437
E	SER519
E	GLY520
E	THR522

---

site_id	AE3
Number of Residues	5
Details	binding site for residue K F 601

Chain	Residue
F	ASN75
F	SER77
F	ASP113
F	THR114
F	GLU118

---

site_id	AE4
Number of Residues	3
Details	binding site for residue MG F 602

Chain	Residue
F	LYS270
F	GLU272
F	ASP296

---

site_id	AE5
Number of Residues	6
Details	binding site for residue SER F 603

Chain	Residue
F	ARG43
F	ASN70
F	ARG106
F	HIS464
F	ILE469
F	PHE470

---

site_id	AE6
Number of Residues	8
Details	binding site for residue PO4 F 604

Chain	Residue
F	THR432
F	LYS433
F	SER434
F	ARG436
F	SER437
F	SER519
F	GLY520
F	THR522

---

site_id	AE7
Number of Residues	6
Details	binding site for residue K G 601

Chain	Residue
G	ASN75
G	SER77
G	ASP113
G	THR114
G	GLU118
G	SER243

---

site_id	AE8
Number of Residues	3
Details	binding site for residue MG G 602

Chain	Residue
G	LYS270
G	GLU272
G	ASP296

---

site_id	AE9
Number of Residues	7
Details	binding site for residue SER G 603

Chain	Residue
G	ARG43
G	ASN44
G	ASN70
G	ARG106
G	HIS464
G	ILE469
G	PHE470

---

site_id	AF1
Number of Residues	9
Details	binding site for residue PO4 G 604

Chain	Residue
G	THR432
G	LYS433
G	SER434
G	GLY435
G	ARG436
G	SER437
G	SER519
G	GLY520
G	THR522

---

site_id	AF2
Number of Residues	5
Details	binding site for residue K H 601

Chain	Residue
H	ASN75
H	SER77
H	ASP113
H	THR114
H	GLU118

---

site_id	AF3
Number of Residues	3
Details	binding site for residue MG H 602

Chain	Residue
H	LYS270
H	GLU272
H	ASP296

---

site_id	AF4
Number of Residues	7
Details	binding site for residue SER H 603

Chain	Residue
H	ARG43
H	ASN44
H	ASN70
H	ARG106
H	HIS464
H	ILE469
H	PHE470

---

site_id	AF5
Number of Residues	8
Details	binding site for residue PO4 H 604

Chain	Residue
H	THR432
H	LYS433
H	SER434
H	ARG436
H	SER437
H	SER519
H	GLY520
H	THR522

---

Functional Information from PROSITE/UniProt

site_id	PS00110
Number of Residues	13
Details	PYRUVATE_KINASE Pyruvate kinase active site signature. IkIISKIENhEGV

Chain	Residue	Details
A	ILE265-VAL277

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	352
Details	Region: {"description":"Intersubunit contact"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23064226","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P30613","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	80
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23530218","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FXF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15996096","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23530218","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T5A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FXF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"P00549","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Site: {"description":"Crucial for phosphotyrosine binding","evidences":[{"source":"PubMed","id":"27199445","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18088087","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	16
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P52480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	16
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P11980","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P52480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	16
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P52480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P52480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"21700219","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	16
Details	Modified residue: {"description":"4-hydroxyproline","evidences":[{"source":"PubMed","id":"21620138","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	16
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"30487609","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"24120661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26787900","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P52480","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	24
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---