Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005125 | molecular_function | cytokine activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006915 | biological_process | apoptotic process |
A | 0007165 | biological_process | signal transduction |
A | 0008284 | biological_process | positive regulation of cell population proliferation |
A | 0008285 | biological_process | negative regulation of cell population proliferation |
A | 0030336 | biological_process | negative regulation of cell migration |
A | 0042531 | biological_process | positive regulation of tyrosine phosphorylation of STAT protein |
A | 0071222 | biological_process | cellular response to lipopolysaccharide |
A | 0071353 | biological_process | cellular response to interleukin-4 |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue NI A 301 |
Chain | Residue |
A | HIS125 |
A | SER162 |
A | HIS167 |
A | HOH485 |
A | HOH529 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residues SO4 A 302 and SO4 A 303 |
Chain | Residue |
A | ARG168 |
A | ARG168 |
A | ARG175 |
A | ARG175 |
A | HOH401 |
A | HOH412 |
A | HOH412 |
A | HOH463 |
A | HIS55 |
A | HIS55 |
A | ARG60 |
A | ARG60 |
site_id | AC3 |
Number of Residues | 12 |
Details | binding site for residues SO4 A 302 and SO4 A 303 |
Chain | Residue |
A | HIS55 |
A | HIS55 |
A | ARG60 |
A | ARG60 |
A | ARG168 |
A | ARG168 |
A | ARG175 |
A | ARG175 |
A | HOH401 |
A | HOH412 |
A | HOH412 |
A | HOH463 |
Functional Information from PROSITE/UniProt
site_id | PS00520 |
Number of Residues | 21 |
Details | INTERLEUKIN_10 Interleukin-10 family signature. SdaesCYlvhqLLrFYLdTVF |
Chain | Residue | Details |
A | SER101-PHE121 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN85 | |
A | ASN99 | |
A | ASN126 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23078624 |
Chain | Residue | Details |
A | LYS122 | |