6GFP
cyanobacterial GAPDH with NADP bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 40 |
| Details | binding site for residue NAP A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | ALA99 |
| A | THR100 |
| A | GLY101 |
| A | PHE103 |
| A | THR123 |
| A | ALA124 |
| A | ASN317 |
| A | TYR321 |
| A | NAD1002 |
| A | FMT1004 |
| A | PHE9 |
| A | HOH1101 |
| A | HOH1105 |
| A | HOH1110 |
| A | HOH1113 |
| A | HOH1115 |
| A | HOH1123 |
| A | HOH1136 |
| A | HOH1137 |
| A | HOH1138 |
| A | HOH1153 |
| A | GLY10 |
| A | HOH1172 |
| A | HOH1209 |
| A | HOH1224 |
| A | HOH1230 |
| A | HOH1246 |
| A | HOH1252 |
| A | HOH1276 |
| A | HOH1277 |
| B | HOH1186 |
| B | HOH1194 |
| A | ARG11 |
| B | HOH1201 |
| A | ILE12 |
| A | ASN35 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | binding site for residue NAD A 1002 |
| Chain | Residue |
| A | GLY8 |
| A | PHE9 |
| A | GLY10 |
| A | ARG11 |
| A | ILE12 |
| A | ASN35 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| A | ALA99 |
| A | THR100 |
| A | GLY101 |
| A | THR123 |
| A | ALA124 |
| A | CYS154 |
| A | ASN317 |
| A | TYR321 |
| A | NAP1001 |
| A | FMT1004 |
| A | HOH1101 |
| A | HOH1110 |
| A | HOH1113 |
| A | HOH1115 |
| A | HOH1123 |
| A | HOH1137 |
| A | HOH1138 |
| A | HOH1142 |
| A | HOH1153 |
| A | HOH1172 |
| A | HOH1224 |
| A | HOH1230 |
| A | HOH1246 |
| A | HOH1277 |
| B | HOH1194 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue MLI A 1003 |
| Chain | Residue |
| A | SER153 |
| A | THR155 |
| A | ARG199 |
| A | THR212 |
| A | GLY213 |
| A | ARG235 |
| A | FMT1004 |
| A | HOH1109 |
| A | HOH1214 |
| A | HOH1223 |
| A | HOH1229 |
| A | HOH1358 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue FMT A 1004 |
| Chain | Residue |
| A | THR184 |
| A | ARG199 |
| A | ARG235 |
| A | NAP1001 |
| A | NAD1002 |
| A | MLI1003 |
| A | HOH1109 |
| A | HOH1326 |
| site_id | AC5 |
| Number of Residues | 36 |
| Details | binding site for residue NAP B 1001 |
| Chain | Residue |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | PHE103 |
| B | THR123 |
| B | ALA124 |
| B | ASN317 |
| B | TYR321 |
| B | NAD1002 |
| B | HOH1102 |
| B | HOH1111 |
| B | HOH1119 |
| B | HOH1123 |
| B | HOH1127 |
| B | HOH1152 |
| B | HOH1164 |
| B | HOH1168 |
| B | HOH1198 |
| B | HOH1210 |
| B | HOH1218 |
| B | HOH1220 |
| B | HOH1234 |
| B | HOH1240 |
| B | HOH1282 |
| A | SER193 |
| A | HOH1210 |
| A | HOH1212 |
| B | GLY8 |
| B | PHE9 |
| site_id | AC6 |
| Number of Residues | 33 |
| Details | binding site for residue NAD B 1002 |
| Chain | Residue |
| B | GLY8 |
| B | PHE9 |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | THR123 |
| B | ALA124 |
| B | CYS154 |
| B | THR184 |
| B | ASN317 |
| B | TYR321 |
| B | NAP1001 |
| B | HOH1102 |
| B | HOH1113 |
| B | HOH1119 |
| B | HOH1123 |
| B | HOH1127 |
| B | HOH1152 |
| B | HOH1164 |
| B | HOH1168 |
| B | HOH1198 |
| B | HOH1213 |
| B | HOH1218 |
| B | HOH1220 |
| B | HOH1234 |
| B | HOH1282 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue MLI B 1003 |
| Chain | Residue |
| B | SER153 |
| B | THR155 |
| B | ARG199 |
| B | THR212 |
| B | GLY213 |
| B | ARG235 |
| B | HOH1109 |
| B | HOH1200 |
| B | HOH1209 |
| B | HOH1222 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1004 |
| Chain | Residue |
| A | ALA334 |
| A | HOH1198 |
| B | SER114 |
| B | HOH1219 |
| B | HOH1326 |
| B | HOH1327 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA152-LEU159 |
