6GFK

delta-N METTL16 MTase domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
B	0008168	molecular_function	methyltransferase activity
C	0008168	molecular_function	methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue SAH A 301

Chain	Residue
A	ASN45
A	ASP135
A	CYS138
A	THR164
A	LEU165
A	ASN184
A	PRO186
A	HOH406
A	HOH408
A	HOH412
A	HOH422
A	LEU75
A	HOH426
A	ARG82
A	GLY110
A	THR111
A	TYR117
A	THR132
A	GLU133
A	VAL134

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 302

Chain	Residue
A	LYS47
A	ARG82
A	ASN184
A	ARG282
A	HOH405

---

site_id	AC3
Number of Residues	1
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG53

---

site_id	AC4
Number of Residues	20
Details	binding site for residue SAH B 301

Chain	Residue
B	LEU75
B	ARG82
B	GLY110
B	THR111
B	THR132
B	GLU133
B	VAL134
B	ASP135
B	THR164
B	LEU165
B	ASN184
B	PRO186
B	PHE188
B	HOH401
B	HOH408
B	HOH412
B	HOH415
B	HOH417
C	ASN45
C	HOH415

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 B 302

Chain	Residue
B	LEU75
B	ARG82
B	ASN184
B	ARG282
C	LYS47
C	ARG279

---

site_id	AC6
Number of Residues	1
Details	binding site for residue SO4 B 303

Chain	Residue
B	ARG53

---

site_id	AC7
Number of Residues	19
Details	binding site for residue SAH C 301

Chain	Residue
B	ASN45
B	HOH410
C	LEU75
C	ARG82
C	GLY110
C	THR111
C	THR132
C	GLU133
C	VAL134
C	ASP135
C	CYS138
C	THR164
C	ASN184
C	PRO186
C	PHE188
C	HOH403
C	HOH407
C	HOH409
C	HOH410

---

site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 C 302

Chain	Residue
B	LYS47
B	ARG279
C	LEU75
C	ARG82
C	ASN184
C	ARG282

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:29593291, ECO:0000269|PubMed:30197299, ECO:0000269|Ref.16, ECO:0007744|PDB:2H00, ECO:0007744|PDB:6B92, ECO:0007744|PDB:6GFK, ECO:0007744|PDB:6GFN

Chain	Residue	Details
A	ARG82
A	GLU133
A	THR164
B	ARG82
B	GLU133
B	THR164
C	ARG82
C	GLU133
C	THR164

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:30197299, ECO:0000269|Ref.16, ECO:0007744|PDB:2H00, ECO:0007744|PDB:6GFK, ECO:0007744|PDB:6GFN

Chain	Residue	Details
A	GLY110
A	ASN184
B	GLY110
B	ASN184
C	GLY110
C	ASN184

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:30197299, ECO:0007744|PDB:6GFN

Chain	Residue	Details
A	SER114
B	SER114
C	SER114

---