6GEV
Mineralocorticoid receptor in complex with (s)-13
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 1101 |
| Chain | Residue |
| A | GLU746 |
| A | HOH1215 |
| A | PRO747 |
| A | GLN776 |
| A | GLN779 |
| A | LEU809 |
| A | LEU810 |
| A | ALA813 |
| A | LYS873 |
| A | HOH1206 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 1102 |
| Chain | Residue |
| A | GLN825 |
| A | PHE826 |
| A | LEU827 |
| A | PHE835 |
| A | GLU837 |
| A | MET840 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 1103 |
| Chain | Residue |
| A | SER808 |
| A | THR880 |
| A | HIS932 |
| A | LEU939 |
| A | HOH1269 |
| A | HOH1275 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue EWN A 1104 |
| Chain | Residue |
| A | LEU769 |
| A | ASN770 |
| A | ALA773 |
| A | GLN776 |
| A | MET807 |
| A | SER811 |
| A | LEU814 |
| A | MET845 |
| A | PHE941 |
| A | CYS942 |
| A | THR945 |
| A | VAL954 |
| A | PHE956 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for coactivator binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15908963","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YA3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 7"} |
| Chain | Residue | Details |
