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6GB5

Structure of H-2Db with truncated SEV peptide and GL

Functional Information from GO Data
ChainGOidnamespacecontents
A0001913biological_processT cell mediated cytotoxicity
A0001916biological_processpositive regulation of T cell mediated cytotoxicity
A0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
A0002485biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006955biological_processimmune response
A0009897cellular_componentexternal side of plasma membrane
A0010977biological_processnegative regulation of neuron projection development
A0016020cellular_componentmembrane
A0019882biological_processantigen processing and presentation
A0030670cellular_componentphagocytic vesicle membrane
A0042612cellular_componentMHC class I protein complex
A0098553cellular_componentlumenal side of endoplasmic reticulum membrane
B0001913biological_processT cell mediated cytotoxicity
B0001916biological_processpositive regulation of T cell mediated cytotoxicity
B0002237biological_processresponse to molecule of bacterial origin
B0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
B0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
B0002502biological_processpeptide antigen assembly with MHC class I protein complex
B0002726biological_processpositive regulation of T cell cytokine production
B0005198molecular_functionstructural molecule activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006826biological_processiron ion transport
B0006879biological_processintracellular iron ion homeostasis
B0006955biological_processimmune response
B0006968biological_processcellular defense response
B0007608biological_processsensory perception of smell
B0007611biological_processlearning or memory
B0009897cellular_componentexternal side of plasma membrane
B0010977biological_processnegative regulation of neuron projection development
B0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
B0030670cellular_componentphagocytic vesicle membrane
B0033077biological_processT cell differentiation in thymus
B0034756biological_processregulation of iron ion transport
B0042026biological_processprotein refolding
B0042612cellular_componentMHC class I protein complex
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042824cellular_componentMHC class I peptide loading complex
B0045646biological_processregulation of erythrocyte differentiation
B0048260biological_processpositive regulation of receptor-mediated endocytosis
B0050680biological_processnegative regulation of epithelial cell proliferation
B0050768biological_processnegative regulation of neurogenesis
B0051289biological_processprotein homotetramerization
B0060586biological_processmulticellular organismal-level iron ion homeostasis
B0071281biological_processcellular response to iron ion
B0071283biological_processcellular response to iron(III) ion
B0071316biological_processcellular response to nicotine
B1990000biological_processamyloid fibril formation
B1990712cellular_componentHFE-transferrin receptor complex
B2000774biological_processpositive regulation of cellular senescence
B2000978biological_processnegative regulation of forebrain neuron differentiation
C0001913biological_processT cell mediated cytotoxicity
C0001916biological_processpositive regulation of T cell mediated cytotoxicity
C0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
C0002485biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0006955biological_processimmune response
C0009897cellular_componentexternal side of plasma membrane
C0010977biological_processnegative regulation of neuron projection development
C0016020cellular_componentmembrane
C0019882biological_processantigen processing and presentation
C0030670cellular_componentphagocytic vesicle membrane
C0042612cellular_componentMHC class I protein complex
C0098553cellular_componentlumenal side of endoplasmic reticulum membrane
D0001913biological_processT cell mediated cytotoxicity
D0001916biological_processpositive regulation of T cell mediated cytotoxicity
D0002237biological_processresponse to molecule of bacterial origin
D0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
D0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
D0002502biological_processpeptide antigen assembly with MHC class I protein complex
D0002726biological_processpositive regulation of T cell cytokine production
D0005198molecular_functionstructural molecule activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006826biological_processiron ion transport
D0006879biological_processintracellular iron ion homeostasis
D0006955biological_processimmune response
D0006968biological_processcellular defense response
D0007608biological_processsensory perception of smell
D0007611biological_processlearning or memory
D0009897cellular_componentexternal side of plasma membrane
D0010977biological_processnegative regulation of neuron projection development
D0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
D0030670cellular_componentphagocytic vesicle membrane
D0033077biological_processT cell differentiation in thymus
D0034756biological_processregulation of iron ion transport
D0042026biological_processprotein refolding
D0042612cellular_componentMHC class I protein complex
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0042824cellular_componentMHC class I peptide loading complex
D0045646biological_processregulation of erythrocyte differentiation
D0048260biological_processpositive regulation of receptor-mediated endocytosis
D0050680biological_processnegative regulation of epithelial cell proliferation
D0050768biological_processnegative regulation of neurogenesis
D0051289biological_processprotein homotetramerization
D0060586biological_processmulticellular organismal-level iron ion homeostasis
D0071281biological_processcellular response to iron ion
D0071283biological_processcellular response to iron(III) ion
D0071316biological_processcellular response to nicotine
D1990000biological_processamyloid fibril formation
D1990712cellular_componentHFE-transferrin receptor complex
D2000774biological_processpositive regulation of cellular senescence
D2000978biological_processnegative regulation of forebrain neuron differentiation
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue SO4 A 401
ChainResidue
AARG121
AMET138
AARG145
AHOH513
BILE1

site_idAC2
Number of Residues1
Detailsbinding site for residue SO4 A 402
ChainResidue
AARG111

site_idAC3
Number of Residues5
Detailsbinding site for residue GOL A 403
ChainResidue
AASN30
AHOH501
AARG6
APHE8
ATYR27

site_idAC4
Number of Residues3
Detailsbinding site for residue SO4 C 401
ChainResidue
CPRO15
CALA89
CGLY90

site_idAC5
Number of Residues2
Detailsbinding site for residue SO4 C 402
ChainResidue
CARG144
CARG145

site_idAC6
Number of Residues1
Detailsbinding site for residue SO4 C 403
ChainResidue
CARG111

site_idAC7
Number of Residues1
Detailsbinding site for residue SO4 C 404
ChainResidue
CTRP167

site_idAC8
Number of Residues3
Detailsbinding site for residue GOL C 405
ChainResidue
CARG6
CTYR27
CASN30

site_idAC9
Number of Residues7
Detailsbinding site for residue GOL D 101
ChainResidue
CARG234
DILE7
DGLN8
DVAL9
DTYR94
DASP96
DMET99

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCRVYH
ChainResidueDetails
ATYR257-HIS263
BTYR78-HIS84

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues568
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
AGLY1-VAL285
CGLY1-VAL285

site_idSWS_FT_FI2
Number of Residues42
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AILE286-MET307
CILE286-MET307

site_idSWS_FT_FI3
Number of Residues60
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
ALYS308-ALA338
CLYS308-ALA338

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine; alternate => ECO:0000250|UniProtKB:P01900
ChainResidueDetails
ASER329
CSER329

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P01900
ChainResidueDetails
ASER332
CSER332

site_idSWS_FT_FI6
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3980466, ECO:0000269|PubMed:7118212
ChainResidueDetails
AASN86
CASN86

site_idSWS_FT_FI7
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305
ChainResidueDetails
AASN176
CASN176

site_idSWS_FT_FI8
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3980466
ChainResidueDetails
AASN256
CASN256

site_idSWS_FT_FI9
Number of Residues4
DetailsCROSSLNK: Glycyl serine ester (Ser-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000305|PubMed:19951915
ChainResidueDetails
ASER329
CSER329

227344

PDB entries from 2024-11-13

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