Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006281 | biological_process | DNA repair |
A | 0006307 | biological_process | DNA alkylation repair |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | binding site for residue ETW A 201 |
Chain | Residue |
A | LEU11 |
A | ARG133 |
A | GLY134 |
A | HOH305 |
A | HOH314 |
A | HOH318 |
A | HOH323 |
A | HOH347 |
A | GLY12 |
A | PHE28 |
A | CYS29 |
A | LEU108 |
A | GLU110 |
A | CYS119 |
A | HIS120 |
A | TYR131 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue SO4 A 202 |
Chain | Residue |
A | LYS8 |
A | TYR13 |
A | TYR69 |
A | PHE71 |
A | ARG72 |
A | HOH338 |
A | HOH346 |
A | HOH348 |
A | HOH363 |
site_id | AC3 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 203 |
Chain | Residue |
A | LYS21 |
A | LYS21 |
A | ASN65 |
A | ASN65 |
A | LYS67 |
A | LYS67 |
Functional Information from PROSITE/UniProt
site_id | PS00374 |
Number of Residues | 7 |
Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVI |
Chain | Residue | Details |
A | ILE117-ILE123 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS119 | |