Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006307 | biological_process | DNA alkylation repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ETW A 201 |
| Chain | Residue |
| A | LEU11 |
| A | ARG133 |
| A | GLY134 |
| A | HOH305 |
| A | HOH314 |
| A | HOH318 |
| A | HOH323 |
| A | HOH347 |
| A | GLY12 |
| A | PHE28 |
| A | CYS29 |
| A | LEU108 |
| A | GLU110 |
| A | CYS119 |
| A | HIS120 |
| A | TYR131 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | LYS8 |
| A | TYR13 |
| A | TYR69 |
| A | PHE71 |
| A | ARG72 |
| A | HOH338 |
| A | HOH346 |
| A | HOH348 |
| A | HOH363 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | LYS21 |
| A | LYS21 |
| A | ASN65 |
| A | ASN65 |
| A | LYS67 |
| A | LYS67 |
Functional Information from PROSITE/UniProt
| site_id | PS00374 |
| Number of Residues | 7 |
| Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVI |
| Chain | Residue | Details |
| A | ILE117-ILE123 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; methyl group acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00772","evidenceCode":"ECO:0000255"}]} |
