6G1S
CryoEM structure of the MDA5-dsRNA filament with 87-degree helical twist
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1101 |
| Chain | Residue |
| A | CYS907 |
| A | CYS910 |
| A | CYS962 |
| A | CYS964 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01125 |
| Chain | Residue | Details |
| A | HIS974 | |
| A | LEU977 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | ARG338 | |
| A | ALA340 | |
| A | LYS351 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | PHE712 | |
| A | SER715 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by RIOK3 => ECO:0000250|UniProtKB:Q9BYX4 |
| Chain | Residue | Details |
| A | GLN895 |
