6FZX
LasB, hydroxymate Inhibitor Complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue EEK A 401 |
| Chain | Residue |
| A | ASN112 |
| A | HIS223 |
| A | HIS224 |
| A | TYR234 |
| A | LEU235 |
| A | ASN238 |
| A | ZN402 |
| A | HOH614 |
| A | ALA113 |
| A | TYR114 |
| A | HIS140 |
| A | GLU141 |
| A | HIS144 |
| A | TYR155 |
| A | GLU164 |
| A | ASP221 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | HIS140 |
| A | HIS144 |
| A | TYR155 |
| A | GLU164 |
| A | EEK401 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP136 |
| A | GLU172 |
| A | GLU175 |
| A | ASP183 |
| A | LEU185 |
| A | HOH586 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | GLN10 |
| A | ARG29 |
| A | GLN65 |
| A | ASN67 |
| A | GLY68 |
| A | HOH532 |
| A | HOH582 |
| A | HOH603 |
| A | HOH682 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | GLY35 |
| A | ASN36 |
| A | PHE84 |
| A | SER94 |
| A | LEU96 |
| A | HIS98 |
| A | LYS99 |
| A | LEU100 |
| A | HOH579 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEVSHGF |
| Chain | Residue | Details |
| A | VAL137-PHE146 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"1899664","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"PDB data bank","title":"Elastase of Pseudomonas aeruginosa with an inhibitor.","authors":["Bitto E.","McKay D.B."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2008","submissionDatabase":"PDB data bank","title":"Structure of the elastase of Pseudomonas aeruginosa complexed with phosphoramidon.","authors":["Overgaard M.T.","McKay D.B."]}}]} |
| Chain | Residue | Details |
