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6FZJ

PPAR gamma mutant complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue EDK A 550
ChainResidue
APHE310
AMET392
AHIS477
ALEU481
ALEU497
ATYR501
AHOH688
AGLY312
ACYS313
AGLN314
ASER317
AHIS351
AILE369
APHE388
APHE391

site_idAC2
Number of Residues1
Detailsbinding site for residue IOD A 551
ChainResidue
ASER370

site_idAC3
Number of Residues3
Detailsbinding site for residue CL A 552
ChainResidue
AASN403
AHOH628
AHOH729

site_idAC4
Number of Residues1
Detailsbinding site for residue CL A 553
ChainResidue
AGLN311

site_idAC5
Number of Residues3
Detailsbinding site for residue CL A 554
ChainResidue
AHIS453
APRO454
AGLU455

site_idAC6
Number of Residues14
Detailsbinding site for residue EDK B 550
ChainResidue
BPHE310
BGLY312
BCYS313
BGLN314
BSER317
BHIS351
BTYR355
BILE369
BPHE388
BPHE391
BHIS477
BTYR501
BHOH622
BHOH644

site_idAC7
Number of Residues2
Detailsbinding site for residue CL B 552
ChainResidue
BASN403
BHOH726

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN314
AHIS351
AHIS477
ATYR501
BGLN314
BHIS351
BHIS477
BTYR501

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
ALYS252
BLYS252

227111

PDB entries from 2024-11-06

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