6FY5
Crystal structure of the macro domain of human macroh2a2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 1000 |
| Chain | Residue |
| A | GLU287 |
| A | GLU288 |
| A | GLU291 |
| A | LYS332 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1001 |
| Chain | Residue |
| A | TYR362 |
| A | HOH1122 |
| A | PHE311 |
| A | PRO312 |
| A | PRO313 |
| A | PHE314 |
| A | LEU352 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 1000 |
| Chain | Residue |
| B | GLY282 |
| B | SER283 |
| B | GLU287 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 1001 |
| Chain | Residue |
| B | PHE311 |
| B | PRO312 |
| B | PRO313 |
| B | PHE351 |
| B | LEU352 |
| B | LEU353 |
| B | TYR362 |
| B | EDO1002 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 1002 |
| Chain | Residue |
| B | PRO313 |
| B | PHE314 |
| B | LEU353 |
| B | SER358 |
| B | TYR362 |
| B | EDO1001 |
| B | HOH1134 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 372 |
| Details | Domain: {"description":"Macro","evidences":[{"source":"PROSITE-ProRule","id":"PRU00490","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
