6FQV
2.60A BINARY COMPLEX OF S.AUREUS GYRASE with UNCLEAVED DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006265 | biological_process | DNA topological change |
| R | 0003677 | molecular_function | DNA binding |
| R | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| R | 0005524 | molecular_function | ATP binding |
| R | 0006259 | biological_process | DNA metabolic process |
| R | 0006265 | biological_process | DNA topological change |
| S | 0003677 | molecular_function | DNA binding |
| S | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| S | 0005524 | molecular_function | ATP binding |
| S | 0006265 | biological_process | DNA topological change |
| T | 0003677 | molecular_function | DNA binding |
| T | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| T | 0005524 | molecular_function | ATP binding |
| T | 0006259 | biological_process | DNA metabolic process |
| T | 0006265 | biological_process | DNA topological change |
| U | 0003677 | molecular_function | DNA binding |
| U | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| U | 0005524 | molecular_function | ATP binding |
| U | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | PRO44 |
| A | ARG47 |
| A | ARG48 |
| A | ILE147 |
| A | PRO157 |
| A | HOH616 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | ARG429 |
| A | ARG432 |
| C | ARG429 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | PRO44 |
| C | ARG47 |
| C | ARG48 |
| C | SER158 |
| C | HOH639 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL E 101 |
| Chain | Residue |
| E | DT6 |
| F | DT14 |
| F | DA15 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL F 101 |
| Chain | Residue |
| E | DT14 |
| F | DC4 |
| F | DG5 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL R 501 |
| Chain | Residue |
| R | PRO44 |
| R | ARG47 |
| R | PRO157 |
| R | HOH614 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL R 502 |
| Chain | Residue |
| R | ASP96 |
| R | MET113 |
| R | PRO219 |
| R | ARG485 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL R 503 |
| Chain | Residue |
| R | ASN54 |
| R | GLU55 |
| R | ASN140 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue NA R 504 |
| Chain | Residue |
| R | TYR322 |
| R | LYS323 |
| R | THR325 |
| R | GLN328 |
| R | HOH629 |
| R | HOH667 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL T 501 |
| Chain | Residue |
| T | PRO44 |
| T | ARG47 |
| T | SER158 |
| T | HOH610 |
| T | HOH631 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL T 502 |
| Chain | Residue |
| T | GLU263 |
| T | ARG485 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 T 503 |
| Chain | Residue |
| R | ARG429 |
| T | ARG429 |
| T | ARG432 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue NA T 504 |
| Chain | Residue |
| T | TYR322 |
| T | LYS323 |
| T | THR325 |
| T | GLN328 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL U 701 |
| Chain | Residue |
| T | ASP24 |
| U | ASP510 |
| U | LYS581 |
| U | LEU642 |
| U | HOH811 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL V 101 |
| Chain | Residue |
| V | DT14 |
| W | DG5 |
| W | DT6 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01898 |
| Chain | Residue | Details |
| B | GLU435 | |
| U | GLU435 | |
| U | ASP508 | |
| U | ASP510 | |
| B | ASP508 | |
| B | ASP510 | |
| D | GLU435 | |
| D | ASP508 | |
| D | ASP510 | |
| S | GLU435 | |
| S | ASP508 | |
| S | ASP510 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | SITE: Interaction with DNA => ECO:0000255|HAMAP-Rule:MF_01898 |
| Chain | Residue | Details |
| B | LYS460 | |
| B | ASN463 | |
| D | LYS460 | |
| D | ASN463 | |
| S | LYS460 | |
| S | ASN463 | |
| U | LYS460 | |
| U | ASN463 |
