6FPY
Inter-alpha-inhibitor heavy chain 1, wild type
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | ASP298 |
| A | SER300 |
| A | SER302 |
| A | ASP403 |
| A | HOH1185 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 1002 |
| Chain | Residue |
| A | ASP269 |
| A | PHE280 |
| A | PHE281 |
| A | ALA282 |
| A | ARG65 |
| A | ARG264 |
| A | LYS266 |
| A | ILE267 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1003 |
| Chain | Residue |
| A | SER73 |
| A | ALA86 |
| A | PHE87 |
| A | ASP88 |
| A | HOH1234 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1004 |
| Chain | Residue |
| A | HIS68 |
| A | SER98 |
| A | ASP99 |
| A | GLU165 |
| A | ARG564 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 1001 |
| Chain | Residue |
| B | SER300 |
| B | SER302 |
| B | ASP403 |
| B | HOH1110 |
| B | HOH1234 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1002 |
| Chain | Residue |
| B | THR94 |
| B | GLU166 |
| B | VAL167 |
| B | LEU168 |
| B | LYS169 |
| B | GLU176 |
| B | HOH1179 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 1003 |
| Chain | Residue |
| B | LEU56 |
| B | SER73 |
| B | ALA86 |
| B | PHE87 |
| B | ASP88 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 1004 |
| Chain | Residue |
| B | ARG65 |
| B | GLN200 |
| B | ARG264 |
| B | LYS266 |
| B | ILE267 |
| B | ASP269 |
| B | PHE280 |
| B | PHE281 |
| B | ALA282 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER129 | |
| B | SER129 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | THR402 | |
| A | THR407 | |
| B | THR402 | |
| B | THR407 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Aspartate 1-(chondroitin 4-sulfate)-ester |
| Chain | Residue | Details |
| A | ASP672 | |
| B | ASP672 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: S-linked (Hex...) cysteine => ECO:0000269|PubMed:9425062 |
| Chain | Residue | Details |
| A | CYS60 | |
| B | CYS60 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:9425062, ECO:0000269|PubMed:9677337 |
| Chain | Residue | Details |
| A | ASN285 | |
| B | ASN285 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:9425062, ECO:0000269|PubMed:9677337 |
| Chain | Residue | Details |
| A | ASN588 | |
| B | ASN588 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:9425062 |
| Chain | Residue | Details |
| A | THR653 | |
| B | THR653 |
