6FI9
Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0008270 | molecular_function | zinc ion binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0008270 | molecular_function | zinc ion binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0003677 | molecular_function | DNA binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0008270 | molecular_function | zinc ion binding |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0003677 | molecular_function | DNA binding |
| H | 0003700 | molecular_function | DNA-binding transcription factor activity |
| H | 0006355 | biological_process | regulation of DNA-templated transcription |
| H | 0008270 | molecular_function | zinc ion binding |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 201 |
| Chain | Residue |
| A | GLU23 |
| A | HIS41 |
| A | HIS107 |
| A | HIS111 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 202 |
| Chain | Residue |
| A | CYS29 |
| A | SER31 |
| A | GLU40 |
| A | GLU106 |
| A | HIS107 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 201 |
| Chain | Residue |
| B | GLU23 |
| B | LEU25 |
| B | HIS41 |
| B | HIS107 |
| B | HIS111 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 202 |
| Chain | Residue |
| B | CYS29 |
| B | SER31 |
| B | GLU40 |
| B | GLU106 |
| B | HIS107 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 201 |
| Chain | Residue |
| C | GLU23 |
| C | HIS41 |
| C | HIS107 |
| C | HIS111 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 202 |
| Chain | Residue |
| C | CYS29 |
| C | SER31 |
| C | GLU40 |
| C | GLU106 |
| C | HIS107 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 201 |
| Chain | Residue |
| D | GLU23 |
| D | HIS41 |
| D | HIS107 |
| D | HIS111 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 202 |
| Chain | Residue |
| D | CYS29 |
| D | GLU40 |
| D | GLU106 |
| D | HIS110 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 201 |
| Chain | Residue |
| E | GLU23 |
| E | HIS41 |
| E | HIS107 |
| E | HIS111 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 202 |
| Chain | Residue |
| E | CYS29 |
| E | GLU40 |
| E | GLU106 |
| E | HIS107 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 201 |
| Chain | Residue |
| F | GLU23 |
| F | HIS41 |
| F | HIS107 |
| F | HIS111 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 202 |
| Chain | Residue |
| F | CYS29 |
| F | SER31 |
| F | GLU40 |
| F | GLU106 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 201 |
| Chain | Residue |
| G | GLU23 |
| G | LEU25 |
| G | HIS107 |
| G | HIS111 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN G 202 |
| Chain | Residue |
| G | CYS29 |
| G | SER31 |
| G | GLU40 |
| G | GLU106 |
| G | HIS107 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN H 201 |
| Chain | Residue |
| H | GLU23 |
| H | HIS41 |
| H | HIS107 |
| H | HIS111 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN H 202 |
| Chain | Residue |
| H | CYS29 |
| H | GLU40 |
| H | GLU106 |
| H | HIS107 |
| H | HIS110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 184 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00345 |
| Chain | Residue | Details |
| A | ASN53-GLU76 | |
| B | ASN53-GLU76 | |
| C | ASN53-GLU76 | |
| D | ASN53-GLU76 | |
| E | ASN53-GLU76 | |
| F | ASN53-GLU76 | |
| G | ASN53-GLU76 | |
| H | ASN53-GLU76 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 56 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU23 | |
| B | GLU40 | |
| B | HIS41 | |
| B | GLU106 | |
| B | HIS107 | |
| B | HIS111 | |
| C | GLU23 | |
| C | CYS29 | |
| C | GLU40 | |
| C | HIS41 | |
| C | GLU106 | |
| A | CYS29 | |
| C | HIS107 | |
| C | HIS111 | |
| D | GLU23 | |
| D | CYS29 | |
| D | GLU40 | |
| D | HIS41 | |
| D | GLU106 | |
| D | HIS107 | |
| D | HIS111 | |
| E | GLU23 | |
| A | GLU40 | |
| E | CYS29 | |
| E | GLU40 | |
| E | HIS41 | |
| E | GLU106 | |
| E | HIS107 | |
| E | HIS111 | |
| F | GLU23 | |
| F | CYS29 | |
| F | GLU40 | |
| F | HIS41 | |
| A | HIS41 | |
| F | GLU106 | |
| F | HIS107 | |
| F | HIS111 | |
| G | GLU23 | |
| G | CYS29 | |
| G | GLU40 | |
| G | HIS41 | |
| G | GLU106 | |
| G | HIS107 | |
| G | HIS111 | |
| A | GLU106 | |
| H | GLU23 | |
| H | CYS29 | |
| H | GLU40 | |
| H | HIS41 | |
| H | GLU106 | |
| H | HIS107 | |
| H | HIS111 | |
| A | HIS107 | |
| A | HIS111 | |
| B | GLU23 | |
| B | CYS29 |
