6FI9

Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0046872	molecular_function	metal ion binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0008270	molecular_function	zinc ion binding
C	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0008270	molecular_function	zinc ion binding
D	0046872	molecular_function	metal ion binding
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0008270	molecular_function	zinc ion binding
E	0046872	molecular_function	metal ion binding
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0008270	molecular_function	zinc ion binding
F	0046872	molecular_function	metal ion binding
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
G	0008270	molecular_function	zinc ion binding
G	0046872	molecular_function	metal ion binding
H	0003677	molecular_function	DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006351	biological_process	DNA-templated transcription
H	0006355	biological_process	regulation of DNA-templated transcription
H	0008270	molecular_function	zinc ion binding
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	GLU23
A	HIS41
A	HIS107
A	HIS111

---

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 202

Chain	Residue
A	CYS29
A	SER31
A	GLU40
A	GLU106
A	HIS107

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ZN B 201

Chain	Residue
B	GLU23
B	LEU25
B	HIS41
B	HIS107
B	HIS111

---

site_id	AC4
Number of Residues	5
Details	binding site for residue ZN B 202

Chain	Residue
B	CYS29
B	SER31
B	GLU40
B	GLU106
B	HIS107

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	GLU23
C	HIS41
C	HIS107
C	HIS111

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN C 202

Chain	Residue
C	CYS29
C	SER31
C	GLU40
C	GLU106
C	HIS107

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 201

Chain	Residue
D	GLU23
D	HIS41
D	HIS107
D	HIS111

---

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN D 202

Chain	Residue
D	CYS29
D	GLU40
D	GLU106
D	HIS110

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN E 201

Chain	Residue
E	GLU23
E	HIS41
E	HIS107
E	HIS111

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN E 202

Chain	Residue
E	CYS29
E	GLU40
E	GLU106
E	HIS107

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN F 201

Chain	Residue
F	GLU23
F	HIS41
F	HIS107
F	HIS111

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN F 202

Chain	Residue
F	CYS29
F	SER31
F	GLU40
F	GLU106

---

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN G 201

Chain	Residue
G	GLU23
G	LEU25
G	HIS107
G	HIS111

---

site_id	AD5
Number of Residues	5
Details	binding site for residue ZN G 202

Chain	Residue
G	CYS29
G	SER31
G	GLU40
G	GLU106
G	HIS107

---

site_id	AD6
Number of Residues	4
Details	binding site for residue ZN H 201

Chain	Residue
H	GLU23
H	HIS41
H	HIS107
H	HIS111

---

site_id	AD7
Number of Residues	5
Details	binding site for residue ZN H 202

Chain	Residue
H	CYS29
H	GLU40
H	GLU106
H	HIS107
H	HIS110

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	184
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00345","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---