6F6W
Structure of Mycobacterium smegmatis RNA polymerase core
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| B | 0046983 | molecular_function | protein dimerization activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0032549 | molecular_function | ribonucleoside binding |
| C | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 2001 |
| Chain | Residue |
| D | CYS890 |
| D | ARG962 |
| D | CYS967 |
| D | CYS974 |
| D | CYS977 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 2002 |
| Chain | Residue |
| D | CYS60 |
| D | CYS62 |
| D | CYS75 |
| D | CYS78 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 2003 |
| Chain | Residue |
| D | ASP535 |
| D | ASP537 |
| D | ASP539 |
Functional Information from PROSITE/UniProt
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV |
| Chain | Residue | Details |
| C | GLY873-VAL885 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 225 |
| Details | Region: {"description":"Alpha N-terminal domain (alpha-NTD)","evidences":[{"source":"HAMAP-Rule","id":"MF_00059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"6YXU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6YYS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6Z11","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
