Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6EZM

Imidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
A	0005575	cellular_component	cellular_component
A	0008652	biological_process	amino acid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000105	biological_process	L-histidine biosynthetic process
B	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
B	0005575	cellular_component	cellular_component
B	0008652	biological_process	amino acid biosynthetic process
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
C	0000105	biological_process	L-histidine biosynthetic process
C	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
C	0005575	cellular_component	cellular_component
C	0008652	biological_process	amino acid biosynthetic process
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding
D	0000105	biological_process	L-histidine biosynthetic process
D	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
D	0005575	cellular_component	cellular_component
D	0008652	biological_process	amino acid biosynthetic process
D	0016829	molecular_function	lyase activity
D	0046872	molecular_function	metal ion binding
E	0000105	biological_process	L-histidine biosynthetic process
E	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
E	0005575	cellular_component	cellular_component
E	0008652	biological_process	amino acid biosynthetic process
E	0016829	molecular_function	lyase activity
E	0046872	molecular_function	metal ion binding
F	0000105	biological_process	L-histidine biosynthetic process
F	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
F	0005575	cellular_component	cellular_component
F	0008652	biological_process	amino acid biosynthetic process
F	0016829	molecular_function	lyase activity
F	0046872	molecular_function	metal ion binding
G	0000105	biological_process	L-histidine biosynthetic process
G	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
G	0005575	cellular_component	cellular_component
G	0008652	biological_process	amino acid biosynthetic process
G	0016829	molecular_function	lyase activity
G	0046872	molecular_function	metal ion binding
H	0000105	biological_process	L-histidine biosynthetic process
H	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
H	0005575	cellular_component	cellular_component
H	0008652	biological_process	amino acid biosynthetic process
H	0016829	molecular_function	lyase activity
H	0046872	molecular_function	metal ion binding
I	0000105	biological_process	L-histidine biosynthetic process
I	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
I	0005575	cellular_component	cellular_component
I	0008652	biological_process	amino acid biosynthetic process
I	0016829	molecular_function	lyase activity
I	0046872	molecular_function	metal ion binding
J	0000105	biological_process	L-histidine biosynthetic process
J	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
J	0005575	cellular_component	cellular_component
J	0008652	biological_process	amino acid biosynthetic process
J	0016829	molecular_function	lyase activity
J	0046872	molecular_function	metal ion binding
K	0000105	biological_process	L-histidine biosynthetic process
K	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
K	0005575	cellular_component	cellular_component
K	0008652	biological_process	amino acid biosynthetic process
K	0016829	molecular_function	lyase activity
K	0046872	molecular_function	metal ion binding
L	0000105	biological_process	L-histidine biosynthetic process
L	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
L	0005575	cellular_component	cellular_component
L	0008652	biological_process	amino acid biosynthetic process
L	0016829	molecular_function	lyase activity
L	0046872	molecular_function	metal ion binding
M	0000105	biological_process	L-histidine biosynthetic process
M	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
M	0005575	cellular_component	cellular_component
M	0008652	biological_process	amino acid biosynthetic process
M	0016829	molecular_function	lyase activity
M	0046872	molecular_function	metal ion binding
N	0000105	biological_process	L-histidine biosynthetic process
N	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
N	0005575	cellular_component	cellular_component
N	0008652	biological_process	amino acid biosynthetic process
N	0016829	molecular_function	lyase activity
N	0046872	molecular_function	metal ion binding
O	0000105	biological_process	L-histidine biosynthetic process
O	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
O	0005575	cellular_component	cellular_component
O	0008652	biological_process	amino acid biosynthetic process
O	0016829	molecular_function	lyase activity
O	0046872	molecular_function	metal ion binding
P	0000105	biological_process	L-histidine biosynthetic process
P	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
P	0005575	cellular_component	cellular_component
P	0008652	biological_process	amino acid biosynthetic process
P	0016829	molecular_function	lyase activity
P	0046872	molecular_function	metal ion binding
Q	0000105	biological_process	L-histidine biosynthetic process
Q	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
Q	0005575	cellular_component	cellular_component
Q	0008652	biological_process	amino acid biosynthetic process
Q	0016829	molecular_function	lyase activity
Q	0046872	molecular_function	metal ion binding
R	0000105	biological_process	L-histidine biosynthetic process
R	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
R	0005575	cellular_component	cellular_component
R	0008652	biological_process	amino acid biosynthetic process
R	0016829	molecular_function	lyase activity
R	0046872	molecular_function	metal ion binding
S	0000105	biological_process	L-histidine biosynthetic process
S	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
S	0005575	cellular_component	cellular_component
S	0008652	biological_process	amino acid biosynthetic process
S	0016829	molecular_function	lyase activity
S	0046872	molecular_function	metal ion binding
T	0000105	biological_process	L-histidine biosynthetic process
T	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
T	0005575	cellular_component	cellular_component
T	0008652	biological_process	amino acid biosynthetic process
T	0016829	molecular_function	lyase activity
T	0046872	molecular_function	metal ion binding
U	0000105	biological_process	L-histidine biosynthetic process
U	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
U	0005575	cellular_component	cellular_component
U	0008652	biological_process	amino acid biosynthetic process
U	0016829	molecular_function	lyase activity
U	0046872	molecular_function	metal ion binding
V	0000105	biological_process	L-histidine biosynthetic process
V	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
V	0005575	cellular_component	cellular_component
V	0008652	biological_process	amino acid biosynthetic process
V	0016829	molecular_function	lyase activity
V	0046872	molecular_function	metal ion binding
W	0000105	biological_process	L-histidine biosynthetic process
W	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
W	0005575	cellular_component	cellular_component
W	0008652	biological_process	amino acid biosynthetic process
W	0016829	molecular_function	lyase activity
W	0046872	molecular_function	metal ion binding
X	0000105	biological_process	L-histidine biosynthetic process
X	0004424	molecular_function	imidazoleglycerol-phosphate dehydratase activity
X	0005575	cellular_component	cellular_component
X	0008652	biological_process	amino acid biosynthetic process
X	0016829	molecular_function	lyase activity
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN U 301

Chain	Residue
L	HIS187
U	5LD306
U	HIS90
U	GLU94
U	HIS162

site_id	AC2
Number of Residues	5
Details	binding site for residue MN U 302

Chain	Residue
U	5LD303
D	HIS91
U	HIS64
U	HIS186
U	GLU190

site_id	AC3
Number of Residues	16
Details	binding site for residue 5LD U 303

Chain	Residue
D	HIS90
D	HIS91
D	GLU94
U	MN304
S	ARG116
S	ARG138
S	SER214
S	THR215
S	LYS216
U	HIS64
U	LEU124
U	HIS186
U	HIS187
U	GLU190
U	LYS194
U	MN302

site_id	AC4
Number of Residues	5
Details	binding site for residue MN A 401

Chain	Residue
A	HIS64
A	HIS186
A	GLU190
A	5LD402
Q	HIS91

site_id	AC5
Number of Residues	15
Details	binding site for residue 5LD A 402

Chain	Residue
A	HIS64
A	HIS186
A	HIS187
A	GLU190
A	LYS194
A	MN401
L	ARG116
L	ARG138
L	SER214
L	THR215
L	LYS216
Q	HIS90
Q	HIS91
Q	GLU94
A	MN404

site_id	AC6
Number of Residues	5
Details	binding site for residue MN A 403

Chain	Residue
A	HIS90
A	GLU94
A	HIS162
V	HIS187
A	5LD406

site_id	AC7
Number of Residues	5
Details	binding site for residue MN B 301

Chain	Residue
B	HIS90
B	GLU94
B	HIS162
F	HIS187
B	5LD305

site_id	AC8
Number of Residues	5
Details	binding site for residue MN B 302

Chain	Residue
B	HIS64
B	HIS186
B	GLU190
B	5LD303
N	HIS91

site_id	AC9
Number of Residues	15
Details	binding site for residue 5LD B 303

Chain	Residue
B	HIS64
B	HIS186
B	HIS187
B	GLU190
B	LYS194
B	MN302
N	HIS90
N	HIS91
N	GLU94
B	MN306
V	ARG116
V	ARG138
V	SER214
V	THR215
V	LYS216

site_id	AD1
Number of Residues	5
Details	binding site for residue MN C 301

Chain	Residue
C	HIS90
C	GLU94
C	HIS162
S	HIS187
C	5LD305

site_id	AD2
Number of Residues	5
Details	binding site for residue MN C 302

Chain	Residue
C	HIS64
C	HIS186
C	GLU190
C	5LD303
X	HIS91

site_id	AD3
Number of Residues	16
Details	binding site for residue 5LD C 303

Chain	Residue
X	HIS91
X	GLU94
C	MN306
C	HIS64
C	LEU124
C	HIS186
C	HIS187
C	GLU190
C	LYS194
C	MN302
F	ARG116
F	ARG138
F	SER214
F	THR215
F	LYS216
X	HIS90

site_id	AD4
Number of Residues	5
Details	binding site for residue MN D 401

Chain	Residue
D	HIS64
D	HIS186
D	GLU190
D	5LD402
H	HIS91

site_id	AD5
Number of Residues	15
Details	binding site for residue 5LD D 402

Chain	Residue
D	HIS64
D	HIS186
D	HIS187
D	GLU190
D	LYS194
D	MN401
H	HIS90
H	HIS91
H	GLU94
D	MN403
P	ARG116
P	ARG138
P	SER214
P	THR215
P	LYS216

site_id	AD6
Number of Residues	5
Details	binding site for residue MN U 304

Chain	Residue
D	HIS90
D	GLU94
D	HIS162
U	HIS187
U	5LD303

site_id	AD7
Number of Residues	5
Details	binding site for residue MN E 401

Chain	Residue
E	HIS64
E	HIS186
E	GLU190
E	5LD402
R	HIS91

site_id	AD8
Number of Residues	15
Details	binding site for residue 5LD E 402

Chain	Residue
E	HIS64
E	HIS186
E	HIS187
E	GLU190
E	LYS194
E	MN401
R	HIS90
R	HIS91
R	GLU94
E	MN404
U	ARG116
U	ARG138
U	SER214
U	THR215
U	LYS216

site_id	AD9
Number of Residues	5
Details	binding site for residue MN E 403

Chain	Residue
E	HIS90
E	GLU94
E	HIS162
T	HIS187
E	5LD406

site_id	AE1
Number of Residues	5
Details	binding site for residue MN B 304

Chain	Residue
B	HIS91
F	HIS64
F	HIS186
F	GLU190
B	5LD305

site_id	AE2
Number of Residues	15
Details	binding site for residue 5LD B 305

Chain	Residue
B	HIS90
B	HIS91
B	GLU94
B	MN301
F	HIS64
F	HIS186
F	HIS187
F	GLU190
F	LYS194
B	MN304
T	ARG116
T	ARG138
T	SER214
T	THR215
T	LYS216

site_id	AE3
Number of Residues	5
Details	binding site for residue MN F 301

Chain	Residue
F	HIS90
F	GLU94
F	HIS162
J	HIS187
F	5LD303

site_id	AE4
Number of Residues	6
Details	binding site for residue MN G 301

Chain	Residue
G	HIS90
G	GLU94
G	HIS162
G	5LD302
P	ASP125
P	HIS187

site_id	AE5
Number of Residues	16
Details	binding site for residue 5LD G 302

Chain	Residue
G	GLU14
G	HIS90
G	HIS91
G	GLU94
G	MN301
I	ARG116
I	ARG138
I	SER214
I	THR215
I	LYS216
P	HIS64
P	HIS186
P	HIS187
P	GLU190
P	LYS194
G	MN305

site_id	AE6
Number of Residues	5
Details	binding site for residue MN G 303

Chain	Residue
G	HIS64
G	HIS186
G	GLU190
G	5LD304
W	HIS91

site_id	AE7
Number of Residues	15
Details	binding site for residue 5LD G 304

Chain	Residue
G	HIS64
G	HIS186
G	HIS187
G	GLU190
G	LYS194
G	MN303
J	ARG116
J	ARG138
J	SER214
J	THR215
J	LYS216
W	HIS90
W	HIS91
W	GLU94
G	MN306

site_id	AE8
Number of Residues	5
Details	binding site for residue MN D 403

Chain	Residue
D	HIS187
D	5LD402
H	HIS90
H	GLU94
H	HIS162

site_id	AE9
Number of Residues	5
Details	binding site for residue MN H 301

Chain	Residue
H	HIS64
H	HIS186
H	GLU190
H	5LD302
L	HIS91

site_id	AF1
Number of Residues	16
Details	binding site for residue 5LD H 302

Chain	Residue
H	HIS64
H	LEU124
H	HIS186
H	HIS187
H	GLU190
H	LYS194
H	MN301
L	HIS90
L	HIS91
L	GLU94
H	MN303
Q	ARG116
Q	ARG138
Q	SER214
Q	THR215
Q	LYS216

site_id	AF2
Number of Residues	5
Details	binding site for residue MN I 401

Chain	Residue
I	HIS64
I	HIS186
I	GLU190
I	5LD402
S	HIS91

site_id	AF3
Number of Residues	15
Details	binding site for residue 5LD I 402

Chain	Residue
D	ARG116
D	ARG138
D	SER214
D	THR215
D	LYS216
I	HIS64
I	HIS186
I	HIS187
I	GLU190
I	LYS194
I	MN401
S	HIS90
S	HIS91
S	GLU94
I	MN404

site_id	AF4
Number of Residues	5
Details	binding site for residue MN I 403

Chain	Residue
I	HIS90
I	GLU94
I	HIS162
X	HIS187
I	5LD406

site_id	AF5
Number of Residues	5
Details	binding site for residue MN J 301

Chain	Residue
J	HIS90
J	GLU94
J	HIS162
N	HIS187
J	5LD303

site_id	AF6
Number of Residues	5
Details	binding site for residue MN F 302

Chain	Residue
F	HIS91
J	HIS64
J	HIS186
J	GLU190
F	5LD303

site_id	AF7
Number of Residues	16
Details	binding site for residue 5LD F 303

Chain	Residue
F	HIS90
F	HIS91
F	GLU94
F	MN301
J	HIS64
J	LEU124
J	HIS186
J	HIS187
J	GLU190
J	LYS194
F	MN302
X	ARG116
X	ARG138
X	SER214
X	THR215
X	LYS216

site_id	AF8
Number of Residues	5
Details	binding site for residue MN K 301

Chain	Residue
K	HIS90
K	GLU94
K	HIS162
Q	HIS187
K	5LD305

site_id	AF9
Number of Residues	5
Details	binding site for residue MN K 302

Chain	Residue
K	HIS64
K	HIS186
K	GLU190
K	5LD303
V	HIS91

site_id	AG1
Number of Residues	15
Details	binding site for residue 5LD K 303

Chain	Residue
K	HIS64
K	HIS186
K	HIS187
K	GLU190
K	LYS194
K	MN302
N	ARG116
N	ARG138
N	SER214
N	THR215
N	LYS216
V	HIS90
V	HIS91
V	GLU94
K	MN306

site_id	AG2
Number of Residues	5
Details	binding site for residue MN H 303

Chain	Residue
H	HIS187
H	5LD302
L	HIS90
L	GLU94
L	HIS162

site_id	AG3
Number of Residues	5
Details	binding site for residue MN U 305

Chain	Residue
L	HIS64
L	HIS186
L	GLU190
U	5LD306
U	HIS91

site_id	AG4
Number of Residues	16
Details	binding site for residue 5LD U 306

Chain	Residue
L	HIS64
L	LEU124
L	HIS186
L	HIS187
L	GLU190
L	LYS194
U	MN305
R	ARG116
R	ARG138
R	SER214
R	THR215
R	LYS216
U	HIS90
U	HIS91
U	GLU94
U	MN301

site_id	AG5
Number of Residues	5
Details	binding site for residue MN M 401

Chain	Residue
M	HIS64
M	HIS186
M	GLU190
M	5LD402
P	HIS91

site_id	AG6
Number of Residues	16
Details	binding site for residue 5LD M 402

Chain	Residue
H	ARG116
H	ARG138
H	SER214
H	THR215
H	LYS216
M	HIS64
M	LEU124
M	HIS186
M	HIS187
M	GLU190
M	LYS194
M	MN401
P	HIS90
P	HIS91
P	GLU94
M	MN404

site_id	AG7
Number of Residues	5
Details	binding site for residue MN M 403

Chain	Residue
M	HIS90
M	GLU94
M	HIS162
W	HIS187
M	5LD406

site_id	AG8
Number of Residues	5
Details	binding site for residue MN B 306

Chain	Residue
B	HIS187
B	5LD303
N	HIS90
N	GLU94
N	HIS162

site_id	AG9
Number of Residues	5
Details	binding site for residue MN J 302

Chain	Residue
J	HIS91
N	HIS64
N	HIS186
N	GLU190
J	5LD303

site_id	AH1
Number of Residues	15
Details	binding site for residue 5LD J 303

Chain	Residue
J	HIS90
J	HIS91
J	GLU94
J	MN301
N	HIS64
N	HIS186
N	HIS187
N	GLU190
N	LYS194
J	MN302
W	ARG116
W	ARG138
W	SER214
W	THR215
W	LYS216

site_id	AH2
Number of Residues	5
Details	binding site for residue MN O 301

Chain	Residue
O	HIS90
O	GLU94
O	HIS162
R	HIS187
O	5LD305

site_id	AH3
Number of Residues	5
Details	binding site for residue MN O 302

Chain	Residue
O	HIS64
O	HIS186
O	GLU190
O	5LD303
T	HIS91

site_id	AH4
Number of Residues	15
Details	binding site for residue 5LD O 303

Chain	Residue
B	ARG116
B	ARG138
B	SER214
B	THR215
B	LYS216
O	HIS64
O	HIS186
O	HIS187
O	GLU190
O	LYS194
O	MN302
T	HIS90
T	HIS91
T	GLU94
O	MN306

site_id	AH5
Number of Residues	5
Details	binding site for residue MN M 404

Chain	Residue
M	HIS187
M	5LD402
P	HIS90
P	GLU94
P	HIS162

site_id	AH6
Number of Residues	5
Details	binding site for residue MN G 305

Chain	Residue
G	HIS91
G	5LD302
P	HIS64
P	HIS186
P	GLU190

site_id	AH7
Number of Residues	5
Details	binding site for residue MN A 404

Chain	Residue
A	HIS187
A	5LD402
Q	HIS90
Q	GLU94
Q	HIS162

site_id	AH8
Number of Residues	5
Details	binding site for residue MN K 304

Chain	Residue
K	HIS91
Q	HIS64
Q	HIS186
Q	GLU190
K	5LD305

site_id	AH9
Number of Residues	16
Details	binding site for residue 5LD K 305

Chain	Residue
K	HIS90
K	HIS91
K	GLU94
K	MN301
M	ARG116
M	ARG138
M	SER214
M	THR215
M	LYS216
Q	HIS64
Q	LEU124
Q	HIS186
Q	HIS187
Q	GLU190
Q	LYS194
K	MN304

site_id	AI1
Number of Residues	5
Details	binding site for residue MN E 404

Chain	Residue
E	HIS187
E	5LD402
R	HIS90
R	GLU94
R	HIS162

site_id	AI2
Number of Residues	5
Details	binding site for residue MN O 304

Chain	Residue
O	HIS91
R	HIS64
R	HIS186
R	GLU190
O	5LD305

site_id	AI3
Number of Residues	16
Details	binding site for residue 5LD O 305

Chain	Residue
A	ARG116
A	ARG138
A	SER214
A	THR215
A	LYS216
O	HIS90
O	HIS91
O	GLU94
O	MN301
R	HIS64
R	LEU124
R	HIS186
R	HIS187
R	GLU190
R	LYS194
O	MN304

site_id	AI4
Number of Residues	5
Details	binding site for residue MN I 404

Chain	Residue
I	HIS187
I	5LD402
S	HIS90
S	GLU94
S	HIS162

site_id	AI5
Number of Residues	5
Details	binding site for residue MN C 304

Chain	Residue
C	HIS91
S	HIS64
S	HIS186
S	GLU190
C	5LD305

site_id	AI6
Number of Residues	16
Details	binding site for residue 5LD C 305

Chain	Residue
C	HIS90
C	HIS91
C	GLU94
C	MN301
E	ARG116
E	ARG138
E	SER214
E	THR215
E	LYS216
S	HIS64
S	LEU124
S	HIS186
S	HIS187
S	GLU190
S	LYS194
C	MN304

site_id	AI7
Number of Residues	5
Details	binding site for residue MN O 306

Chain	Residue
O	HIS187
O	5LD303
T	HIS90
T	GLU94
T	HIS162

site_id	AI8
Number of Residues	5
Details	binding site for residue MN E 405

Chain	Residue
E	HIS91
T	HIS64
T	HIS186
T	GLU190
E	5LD406

site_id	AI9
Number of Residues	16
Details	binding site for residue 5LD E 406

Chain	Residue
C	ARG116
C	ARG138
C	SER214
C	THR215
C	LYS216
E	HIS90
E	HIS91
E	GLU94
E	MN403
T	HIS64
T	LEU124
T	HIS186
T	HIS187
T	GLU190
T	LYS194
E	MN405

site_id	AJ1
Number of Residues	5
Details	binding site for residue MN K 306

Chain	Residue
K	HIS187
K	5LD303
V	HIS90
V	GLU94
V	HIS162

site_id	AJ2
Number of Residues	5
Details	binding site for residue MN A 405

Chain	Residue
A	HIS91
V	HIS64
V	HIS186
V	GLU190
A	5LD406

site_id	AJ3
Number of Residues	16
Details	binding site for residue 5LD A 406

Chain	Residue
A	HIS90
A	HIS91
A	GLU94
A	MN403
O	ARG116
O	ARG138
O	SER214
O	THR215
O	LYS216
V	HIS64
V	LEU124
V	HIS186
V	HIS187
V	GLU190
V	LYS194
A	MN405

site_id	AJ4
Number of Residues	5
Details	binding site for residue MN G 306

Chain	Residue
G	HIS187
G	5LD304
W	HIS90
W	GLU94
W	HIS162

site_id	AJ5
Number of Residues	5
Details	binding site for residue MN M 405

Chain	Residue
M	HIS91
W	HIS64
W	HIS186
W	GLU190
M	5LD406

site_id	AJ6
Number of Residues	16
Details	binding site for residue 5LD M 406

Chain	Residue
K	ARG116
K	ARG138
K	SER214
K	THR215
K	LYS216
M	HIS90
M	HIS91
M	GLU94
M	MN403
W	HIS64
W	LEU124
W	HIS186
W	HIS187
W	GLU190
W	LYS194
M	MN405

site_id	AJ7
Number of Residues	5
Details	binding site for residue MN C 306

Chain	Residue
C	HIS187
C	5LD303
X	HIS90
X	GLU94
X	HIS162

site_id	AJ8
Number of Residues	5
Details	binding site for residue MN I 405

Chain	Residue
I	HIS91
X	HIS64
X	HIS186
X	GLU190
I	5LD406

site_id	AJ9
Number of Residues	15
Details	binding site for residue 5LD I 406

Chain	Residue
G	ARG116
G	ARG138
G	SER214
G	THR215
G	LYS216
I	HIS90
I	HIS91
I	GLU94
I	MN403
X	HIS64
X	HIS186
X	HIS187
X	GLU190
X	LYS194
I	MN405

Functional Information from PROSITE/UniProt

site_id	PS00954
Number of Residues	14
Details	IGP_DEHYDRATASE_1 Imidazoleglycerol-phosphate dehydratase signature 1. IDdHHttEdcGIAL

Chain	Residue	Details
U	ILE87-LEU100

site_id	PS00955
Number of Residues	13
Details	IGP_DEHYDRATASE_2 Imidazoleglycerol-phosphate dehydratase signature 2. GkNdHHrsESaFK

Chain	Residue	Details
U	GLY182-LYS194

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O23346","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	744
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29434040","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6EZM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)