6EZM
Imidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| A | 0005575 | cellular_component | cellular_component |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| B | 0005575 | cellular_component | cellular_component |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000105 | biological_process | L-histidine biosynthetic process |
| C | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| C | 0005575 | cellular_component | cellular_component |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000105 | biological_process | L-histidine biosynthetic process |
| D | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| D | 0005575 | cellular_component | cellular_component |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000105 | biological_process | L-histidine biosynthetic process |
| E | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| E | 0005575 | cellular_component | cellular_component |
| E | 0016829 | molecular_function | lyase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000105 | biological_process | L-histidine biosynthetic process |
| F | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| F | 0005575 | cellular_component | cellular_component |
| F | 0016829 | molecular_function | lyase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000105 | biological_process | L-histidine biosynthetic process |
| G | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| G | 0005575 | cellular_component | cellular_component |
| G | 0016829 | molecular_function | lyase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000105 | biological_process | L-histidine biosynthetic process |
| H | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| H | 0005575 | cellular_component | cellular_component |
| H | 0016829 | molecular_function | lyase activity |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0000105 | biological_process | L-histidine biosynthetic process |
| I | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| I | 0005575 | cellular_component | cellular_component |
| I | 0016829 | molecular_function | lyase activity |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0000105 | biological_process | L-histidine biosynthetic process |
| J | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| J | 0005575 | cellular_component | cellular_component |
| J | 0016829 | molecular_function | lyase activity |
| J | 0046872 | molecular_function | metal ion binding |
| K | 0000105 | biological_process | L-histidine biosynthetic process |
| K | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| K | 0005575 | cellular_component | cellular_component |
| K | 0016829 | molecular_function | lyase activity |
| K | 0046872 | molecular_function | metal ion binding |
| L | 0000105 | biological_process | L-histidine biosynthetic process |
| L | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| L | 0005575 | cellular_component | cellular_component |
| L | 0016829 | molecular_function | lyase activity |
| L | 0046872 | molecular_function | metal ion binding |
| M | 0000105 | biological_process | L-histidine biosynthetic process |
| M | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| M | 0005575 | cellular_component | cellular_component |
| M | 0016829 | molecular_function | lyase activity |
| M | 0046872 | molecular_function | metal ion binding |
| N | 0000105 | biological_process | L-histidine biosynthetic process |
| N | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| N | 0005575 | cellular_component | cellular_component |
| N | 0016829 | molecular_function | lyase activity |
| N | 0046872 | molecular_function | metal ion binding |
| O | 0000105 | biological_process | L-histidine biosynthetic process |
| O | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| O | 0005575 | cellular_component | cellular_component |
| O | 0016829 | molecular_function | lyase activity |
| O | 0046872 | molecular_function | metal ion binding |
| P | 0000105 | biological_process | L-histidine biosynthetic process |
| P | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| P | 0005575 | cellular_component | cellular_component |
| P | 0016829 | molecular_function | lyase activity |
| P | 0046872 | molecular_function | metal ion binding |
| Q | 0000105 | biological_process | L-histidine biosynthetic process |
| Q | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| Q | 0005575 | cellular_component | cellular_component |
| Q | 0016829 | molecular_function | lyase activity |
| Q | 0046872 | molecular_function | metal ion binding |
| R | 0000105 | biological_process | L-histidine biosynthetic process |
| R | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| R | 0005575 | cellular_component | cellular_component |
| R | 0016829 | molecular_function | lyase activity |
| R | 0046872 | molecular_function | metal ion binding |
| S | 0000105 | biological_process | L-histidine biosynthetic process |
| S | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| S | 0005575 | cellular_component | cellular_component |
| S | 0016829 | molecular_function | lyase activity |
| S | 0046872 | molecular_function | metal ion binding |
| T | 0000105 | biological_process | L-histidine biosynthetic process |
| T | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| T | 0005575 | cellular_component | cellular_component |
| T | 0016829 | molecular_function | lyase activity |
| T | 0046872 | molecular_function | metal ion binding |
| U | 0000105 | biological_process | L-histidine biosynthetic process |
| U | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| U | 0005575 | cellular_component | cellular_component |
| U | 0016829 | molecular_function | lyase activity |
| U | 0046872 | molecular_function | metal ion binding |
| V | 0000105 | biological_process | L-histidine biosynthetic process |
| V | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| V | 0005575 | cellular_component | cellular_component |
| V | 0016829 | molecular_function | lyase activity |
| V | 0046872 | molecular_function | metal ion binding |
| W | 0000105 | biological_process | L-histidine biosynthetic process |
| W | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| W | 0005575 | cellular_component | cellular_component |
| W | 0016829 | molecular_function | lyase activity |
| W | 0046872 | molecular_function | metal ion binding |
| X | 0000105 | biological_process | L-histidine biosynthetic process |
| X | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| X | 0005575 | cellular_component | cellular_component |
| X | 0016829 | molecular_function | lyase activity |
| X | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN U 301 |
| Chain | Residue |
| L | HIS187 |
| U | 5LD306 |
| U | HIS90 |
| U | GLU94 |
| U | HIS162 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MN U 302 |
| Chain | Residue |
| U | 5LD303 |
| D | HIS91 |
| U | HIS64 |
| U | HIS186 |
| U | GLU190 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD U 303 |
| Chain | Residue |
| D | HIS90 |
| D | HIS91 |
| D | GLU94 |
| U | MN304 |
| S | ARG116 |
| S | ARG138 |
| S | SER214 |
| S | THR215 |
| S | LYS216 |
| U | HIS64 |
| U | LEU124 |
| U | HIS186 |
| U | HIS187 |
| U | GLU190 |
| U | LYS194 |
| U | MN302 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | HIS64 |
| A | HIS186 |
| A | GLU190 |
| A | 5LD402 |
| Q | HIS91 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD A 402 |
| Chain | Residue |
| A | HIS64 |
| A | HIS186 |
| A | HIS187 |
| A | GLU190 |
| A | LYS194 |
| A | MN401 |
| L | ARG116 |
| L | ARG138 |
| L | SER214 |
| L | THR215 |
| L | LYS216 |
| Q | HIS90 |
| Q | HIS91 |
| Q | GLU94 |
| A | MN404 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 403 |
| Chain | Residue |
| A | HIS90 |
| A | GLU94 |
| A | HIS162 |
| V | HIS187 |
| A | 5LD406 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 301 |
| Chain | Residue |
| B | HIS90 |
| B | GLU94 |
| B | HIS162 |
| F | HIS187 |
| B | 5LD305 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 302 |
| Chain | Residue |
| B | HIS64 |
| B | HIS186 |
| B | GLU190 |
| B | 5LD303 |
| N | HIS91 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD B 303 |
| Chain | Residue |
| B | HIS64 |
| B | HIS186 |
| B | HIS187 |
| B | GLU190 |
| B | LYS194 |
| B | MN302 |
| N | HIS90 |
| N | HIS91 |
| N | GLU94 |
| B | MN306 |
| V | ARG116 |
| V | ARG138 |
| V | SER214 |
| V | THR215 |
| V | LYS216 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 301 |
| Chain | Residue |
| C | HIS90 |
| C | GLU94 |
| C | HIS162 |
| S | HIS187 |
| C | 5LD305 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 302 |
| Chain | Residue |
| C | HIS64 |
| C | HIS186 |
| C | GLU190 |
| C | 5LD303 |
| X | HIS91 |
| site_id | AD3 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD C 303 |
| Chain | Residue |
| X | HIS91 |
| X | GLU94 |
| C | MN306 |
| C | HIS64 |
| C | LEU124 |
| C | HIS186 |
| C | HIS187 |
| C | GLU190 |
| C | LYS194 |
| C | MN302 |
| F | ARG116 |
| F | ARG138 |
| F | SER214 |
| F | THR215 |
| F | LYS216 |
| X | HIS90 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | HIS64 |
| D | HIS186 |
| D | GLU190 |
| D | 5LD402 |
| H | HIS91 |
| site_id | AD5 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD D 402 |
| Chain | Residue |
| D | HIS64 |
| D | HIS186 |
| D | HIS187 |
| D | GLU190 |
| D | LYS194 |
| D | MN401 |
| H | HIS90 |
| H | HIS91 |
| H | GLU94 |
| D | MN403 |
| P | ARG116 |
| P | ARG138 |
| P | SER214 |
| P | THR215 |
| P | LYS216 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MN U 304 |
| Chain | Residue |
| D | HIS90 |
| D | GLU94 |
| D | HIS162 |
| U | HIS187 |
| U | 5LD303 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 401 |
| Chain | Residue |
| E | HIS64 |
| E | HIS186 |
| E | GLU190 |
| E | 5LD402 |
| R | HIS91 |
| site_id | AD8 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD E 402 |
| Chain | Residue |
| E | HIS64 |
| E | HIS186 |
| E | HIS187 |
| E | GLU190 |
| E | LYS194 |
| E | MN401 |
| R | HIS90 |
| R | HIS91 |
| R | GLU94 |
| E | MN404 |
| U | ARG116 |
| U | ARG138 |
| U | SER214 |
| U | THR215 |
| U | LYS216 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 403 |
| Chain | Residue |
| E | HIS90 |
| E | GLU94 |
| E | HIS162 |
| T | HIS187 |
| E | 5LD406 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 304 |
| Chain | Residue |
| B | HIS91 |
| F | HIS64 |
| F | HIS186 |
| F | GLU190 |
| B | 5LD305 |
| site_id | AE2 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD B 305 |
| Chain | Residue |
| B | HIS90 |
| B | HIS91 |
| B | GLU94 |
| B | MN301 |
| F | HIS64 |
| F | HIS186 |
| F | HIS187 |
| F | GLU190 |
| F | LYS194 |
| B | MN304 |
| T | ARG116 |
| T | ARG138 |
| T | SER214 |
| T | THR215 |
| T | LYS216 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MN F 301 |
| Chain | Residue |
| F | HIS90 |
| F | GLU94 |
| F | HIS162 |
| J | HIS187 |
| F | 5LD303 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue MN G 301 |
| Chain | Residue |
| G | HIS90 |
| G | GLU94 |
| G | HIS162 |
| G | 5LD302 |
| P | ASP125 |
| P | HIS187 |
| site_id | AE5 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD G 302 |
| Chain | Residue |
| G | GLU14 |
| G | HIS90 |
| G | HIS91 |
| G | GLU94 |
| G | MN301 |
| I | ARG116 |
| I | ARG138 |
| I | SER214 |
| I | THR215 |
| I | LYS216 |
| P | HIS64 |
| P | HIS186 |
| P | HIS187 |
| P | GLU190 |
| P | LYS194 |
| G | MN305 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue MN G 303 |
| Chain | Residue |
| G | HIS64 |
| G | HIS186 |
| G | GLU190 |
| G | 5LD304 |
| W | HIS91 |
| site_id | AE7 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD G 304 |
| Chain | Residue |
| G | HIS64 |
| G | HIS186 |
| G | HIS187 |
| G | GLU190 |
| G | LYS194 |
| G | MN303 |
| J | ARG116 |
| J | ARG138 |
| J | SER214 |
| J | THR215 |
| J | LYS216 |
| W | HIS90 |
| W | HIS91 |
| W | GLU94 |
| G | MN306 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 403 |
| Chain | Residue |
| D | HIS187 |
| D | 5LD402 |
| H | HIS90 |
| H | GLU94 |
| H | HIS162 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue MN H 301 |
| Chain | Residue |
| H | HIS64 |
| H | HIS186 |
| H | GLU190 |
| H | 5LD302 |
| L | HIS91 |
| site_id | AF1 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD H 302 |
| Chain | Residue |
| H | HIS64 |
| H | LEU124 |
| H | HIS186 |
| H | HIS187 |
| H | GLU190 |
| H | LYS194 |
| H | MN301 |
| L | HIS90 |
| L | HIS91 |
| L | GLU94 |
| H | MN303 |
| Q | ARG116 |
| Q | ARG138 |
| Q | SER214 |
| Q | THR215 |
| Q | LYS216 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue MN I 401 |
| Chain | Residue |
| I | HIS64 |
| I | HIS186 |
| I | GLU190 |
| I | 5LD402 |
| S | HIS91 |
| site_id | AF3 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD I 402 |
| Chain | Residue |
| D | ARG116 |
| D | ARG138 |
| D | SER214 |
| D | THR215 |
| D | LYS216 |
| I | HIS64 |
| I | HIS186 |
| I | HIS187 |
| I | GLU190 |
| I | LYS194 |
| I | MN401 |
| S | HIS90 |
| S | HIS91 |
| S | GLU94 |
| I | MN404 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue MN I 403 |
| Chain | Residue |
| I | HIS90 |
| I | GLU94 |
| I | HIS162 |
| X | HIS187 |
| I | 5LD406 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue MN J 301 |
| Chain | Residue |
| J | HIS90 |
| J | GLU94 |
| J | HIS162 |
| N | HIS187 |
| J | 5LD303 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue MN F 302 |
| Chain | Residue |
| F | HIS91 |
| J | HIS64 |
| J | HIS186 |
| J | GLU190 |
| F | 5LD303 |
| site_id | AF7 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD F 303 |
| Chain | Residue |
| F | HIS90 |
| F | HIS91 |
| F | GLU94 |
| F | MN301 |
| J | HIS64 |
| J | LEU124 |
| J | HIS186 |
| J | HIS187 |
| J | GLU190 |
| J | LYS194 |
| F | MN302 |
| X | ARG116 |
| X | ARG138 |
| X | SER214 |
| X | THR215 |
| X | LYS216 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue MN K 301 |
| Chain | Residue |
| K | HIS90 |
| K | GLU94 |
| K | HIS162 |
| Q | HIS187 |
| K | 5LD305 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue MN K 302 |
| Chain | Residue |
| K | HIS64 |
| K | HIS186 |
| K | GLU190 |
| K | 5LD303 |
| V | HIS91 |
| site_id | AG1 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD K 303 |
| Chain | Residue |
| K | HIS64 |
| K | HIS186 |
| K | HIS187 |
| K | GLU190 |
| K | LYS194 |
| K | MN302 |
| N | ARG116 |
| N | ARG138 |
| N | SER214 |
| N | THR215 |
| N | LYS216 |
| V | HIS90 |
| V | HIS91 |
| V | GLU94 |
| K | MN306 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue MN H 303 |
| Chain | Residue |
| H | HIS187 |
| H | 5LD302 |
| L | HIS90 |
| L | GLU94 |
| L | HIS162 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue MN U 305 |
| Chain | Residue |
| L | HIS64 |
| L | HIS186 |
| L | GLU190 |
| U | 5LD306 |
| U | HIS91 |
| site_id | AG4 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD U 306 |
| Chain | Residue |
| L | HIS64 |
| L | LEU124 |
| L | HIS186 |
| L | HIS187 |
| L | GLU190 |
| L | LYS194 |
| U | MN305 |
| R | ARG116 |
| R | ARG138 |
| R | SER214 |
| R | THR215 |
| R | LYS216 |
| U | HIS90 |
| U | HIS91 |
| U | GLU94 |
| U | MN301 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue MN M 401 |
| Chain | Residue |
| M | HIS64 |
| M | HIS186 |
| M | GLU190 |
| M | 5LD402 |
| P | HIS91 |
| site_id | AG6 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD M 402 |
| Chain | Residue |
| H | ARG116 |
| H | ARG138 |
| H | SER214 |
| H | THR215 |
| H | LYS216 |
| M | HIS64 |
| M | LEU124 |
| M | HIS186 |
| M | HIS187 |
| M | GLU190 |
| M | LYS194 |
| M | MN401 |
| P | HIS90 |
| P | HIS91 |
| P | GLU94 |
| M | MN404 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue MN M 403 |
| Chain | Residue |
| M | HIS90 |
| M | GLU94 |
| M | HIS162 |
| W | HIS187 |
| M | 5LD406 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 306 |
| Chain | Residue |
| B | HIS187 |
| B | 5LD303 |
| N | HIS90 |
| N | GLU94 |
| N | HIS162 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue MN J 302 |
| Chain | Residue |
| J | HIS91 |
| N | HIS64 |
| N | HIS186 |
| N | GLU190 |
| J | 5LD303 |
| site_id | AH1 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD J 303 |
| Chain | Residue |
| J | HIS90 |
| J | HIS91 |
| J | GLU94 |
| J | MN301 |
| N | HIS64 |
| N | HIS186 |
| N | HIS187 |
| N | GLU190 |
| N | LYS194 |
| J | MN302 |
| W | ARG116 |
| W | ARG138 |
| W | SER214 |
| W | THR215 |
| W | LYS216 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue MN O 301 |
| Chain | Residue |
| O | HIS90 |
| O | GLU94 |
| O | HIS162 |
| R | HIS187 |
| O | 5LD305 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue MN O 302 |
| Chain | Residue |
| O | HIS64 |
| O | HIS186 |
| O | GLU190 |
| O | 5LD303 |
| T | HIS91 |
| site_id | AH4 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD O 303 |
| Chain | Residue |
| B | ARG116 |
| B | ARG138 |
| B | SER214 |
| B | THR215 |
| B | LYS216 |
| O | HIS64 |
| O | HIS186 |
| O | HIS187 |
| O | GLU190 |
| O | LYS194 |
| O | MN302 |
| T | HIS90 |
| T | HIS91 |
| T | GLU94 |
| O | MN306 |
| site_id | AH5 |
| Number of Residues | 5 |
| Details | binding site for residue MN M 404 |
| Chain | Residue |
| M | HIS187 |
| M | 5LD402 |
| P | HIS90 |
| P | GLU94 |
| P | HIS162 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue MN G 305 |
| Chain | Residue |
| G | HIS91 |
| G | 5LD302 |
| P | HIS64 |
| P | HIS186 |
| P | GLU190 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 404 |
| Chain | Residue |
| A | HIS187 |
| A | 5LD402 |
| Q | HIS90 |
| Q | GLU94 |
| Q | HIS162 |
| site_id | AH8 |
| Number of Residues | 5 |
| Details | binding site for residue MN K 304 |
| Chain | Residue |
| K | HIS91 |
| Q | HIS64 |
| Q | HIS186 |
| Q | GLU190 |
| K | 5LD305 |
| site_id | AH9 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD K 305 |
| Chain | Residue |
| K | HIS90 |
| K | HIS91 |
| K | GLU94 |
| K | MN301 |
| M | ARG116 |
| M | ARG138 |
| M | SER214 |
| M | THR215 |
| M | LYS216 |
| Q | HIS64 |
| Q | LEU124 |
| Q | HIS186 |
| Q | HIS187 |
| Q | GLU190 |
| Q | LYS194 |
| K | MN304 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 404 |
| Chain | Residue |
| E | HIS187 |
| E | 5LD402 |
| R | HIS90 |
| R | GLU94 |
| R | HIS162 |
| site_id | AI2 |
| Number of Residues | 5 |
| Details | binding site for residue MN O 304 |
| Chain | Residue |
| O | HIS91 |
| R | HIS64 |
| R | HIS186 |
| R | GLU190 |
| O | 5LD305 |
| site_id | AI3 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD O 305 |
| Chain | Residue |
| A | ARG116 |
| A | ARG138 |
| A | SER214 |
| A | THR215 |
| A | LYS216 |
| O | HIS90 |
| O | HIS91 |
| O | GLU94 |
| O | MN301 |
| R | HIS64 |
| R | LEU124 |
| R | HIS186 |
| R | HIS187 |
| R | GLU190 |
| R | LYS194 |
| O | MN304 |
| site_id | AI4 |
| Number of Residues | 5 |
| Details | binding site for residue MN I 404 |
| Chain | Residue |
| I | HIS187 |
| I | 5LD402 |
| S | HIS90 |
| S | GLU94 |
| S | HIS162 |
| site_id | AI5 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 304 |
| Chain | Residue |
| C | HIS91 |
| S | HIS64 |
| S | HIS186 |
| S | GLU190 |
| C | 5LD305 |
| site_id | AI6 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD C 305 |
| Chain | Residue |
| C | HIS90 |
| C | HIS91 |
| C | GLU94 |
| C | MN301 |
| E | ARG116 |
| E | ARG138 |
| E | SER214 |
| E | THR215 |
| E | LYS216 |
| S | HIS64 |
| S | LEU124 |
| S | HIS186 |
| S | HIS187 |
| S | GLU190 |
| S | LYS194 |
| C | MN304 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue MN O 306 |
| Chain | Residue |
| O | HIS187 |
| O | 5LD303 |
| T | HIS90 |
| T | GLU94 |
| T | HIS162 |
| site_id | AI8 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 405 |
| Chain | Residue |
| E | HIS91 |
| T | HIS64 |
| T | HIS186 |
| T | GLU190 |
| E | 5LD406 |
| site_id | AI9 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD E 406 |
| Chain | Residue |
| C | ARG116 |
| C | ARG138 |
| C | SER214 |
| C | THR215 |
| C | LYS216 |
| E | HIS90 |
| E | HIS91 |
| E | GLU94 |
| E | MN403 |
| T | HIS64 |
| T | LEU124 |
| T | HIS186 |
| T | HIS187 |
| T | GLU190 |
| T | LYS194 |
| E | MN405 |
| site_id | AJ1 |
| Number of Residues | 5 |
| Details | binding site for residue MN K 306 |
| Chain | Residue |
| K | HIS187 |
| K | 5LD303 |
| V | HIS90 |
| V | GLU94 |
| V | HIS162 |
| site_id | AJ2 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 405 |
| Chain | Residue |
| A | HIS91 |
| V | HIS64 |
| V | HIS186 |
| V | GLU190 |
| A | 5LD406 |
| site_id | AJ3 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD A 406 |
| Chain | Residue |
| A | HIS90 |
| A | HIS91 |
| A | GLU94 |
| A | MN403 |
| O | ARG116 |
| O | ARG138 |
| O | SER214 |
| O | THR215 |
| O | LYS216 |
| V | HIS64 |
| V | LEU124 |
| V | HIS186 |
| V | HIS187 |
| V | GLU190 |
| V | LYS194 |
| A | MN405 |
| site_id | AJ4 |
| Number of Residues | 5 |
| Details | binding site for residue MN G 306 |
| Chain | Residue |
| G | HIS187 |
| G | 5LD304 |
| W | HIS90 |
| W | GLU94 |
| W | HIS162 |
| site_id | AJ5 |
| Number of Residues | 5 |
| Details | binding site for residue MN M 405 |
| Chain | Residue |
| M | HIS91 |
| W | HIS64 |
| W | HIS186 |
| W | GLU190 |
| M | 5LD406 |
| site_id | AJ6 |
| Number of Residues | 16 |
| Details | binding site for residue 5LD M 406 |
| Chain | Residue |
| K | ARG116 |
| K | ARG138 |
| K | SER214 |
| K | THR215 |
| K | LYS216 |
| M | HIS90 |
| M | HIS91 |
| M | GLU94 |
| M | MN403 |
| W | HIS64 |
| W | LEU124 |
| W | HIS186 |
| W | HIS187 |
| W | GLU190 |
| W | LYS194 |
| M | MN405 |
| site_id | AJ7 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 306 |
| Chain | Residue |
| C | HIS187 |
| C | 5LD303 |
| X | HIS90 |
| X | GLU94 |
| X | HIS162 |
| site_id | AJ8 |
| Number of Residues | 5 |
| Details | binding site for residue MN I 405 |
| Chain | Residue |
| I | HIS91 |
| X | HIS64 |
| X | HIS186 |
| X | GLU190 |
| I | 5LD406 |
| site_id | AJ9 |
| Number of Residues | 15 |
| Details | binding site for residue 5LD I 406 |
| Chain | Residue |
| G | ARG116 |
| G | ARG138 |
| G | SER214 |
| G | THR215 |
| G | LYS216 |
| I | HIS90 |
| I | HIS91 |
| I | GLU94 |
| I | MN403 |
| X | HIS64 |
| X | HIS186 |
| X | HIS187 |
| X | GLU190 |
| X | LYS194 |
| I | MN405 |
Functional Information from PROSITE/UniProt
| site_id | PS00954 |
| Number of Residues | 14 |
| Details | IGP_DEHYDRATASE_1 Imidazoleglycerol-phosphate dehydratase signature 1. IDdHHttEdcGIAL |
| Chain | Residue | Details |
| U | ILE87-LEU100 |
| site_id | PS00955 |
| Number of Residues | 13 |
| Details | IGP_DEHYDRATASE_2 Imidazoleglycerol-phosphate dehydratase signature 2. GkNdHHrsESaFK |
| Chain | Residue | Details |
| U | GLY182-LYS194 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:O23346 |
| Chain | Residue | Details |
| U | GLU14 | |
| D | ARG138 | |
| E | GLU14 | |
| E | ARG138 | |
| F | GLU14 | |
| F | ARG138 | |
| G | GLU14 | |
| G | ARG138 | |
| H | GLU14 | |
| H | ARG138 | |
| I | GLU14 | |
| U | ARG138 | |
| I | ARG138 | |
| J | GLU14 | |
| J | ARG138 | |
| K | GLU14 | |
| K | ARG138 | |
| L | GLU14 | |
| L | ARG138 | |
| M | GLU14 | |
| M | ARG138 | |
| N | GLU14 | |
| A | GLU14 | |
| N | ARG138 | |
| O | GLU14 | |
| O | ARG138 | |
| P | GLU14 | |
| P | ARG138 | |
| Q | GLU14 | |
| Q | ARG138 | |
| R | GLU14 | |
| R | ARG138 | |
| S | GLU14 | |
| A | ARG138 | |
| S | ARG138 | |
| T | GLU14 | |
| T | ARG138 | |
| V | GLU14 | |
| V | ARG138 | |
| W | GLU14 | |
| W | ARG138 | |
| X | GLU14 | |
| X | ARG138 | |
| B | GLU14 | |
| B | ARG138 | |
| C | GLU14 | |
| C | ARG138 | |
| D | GLU14 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 240 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29434040, ECO:0007744|PDB:6EZM |
| Chain | Residue | Details |
| U | HIS64 | |
| U | SER214 | |
| I | SER214 | |
| J | HIS64 | |
| J | HIS90 | |
| J | HIS91 | |
| J | GLU94 | |
| J | ARG116 | |
| J | HIS162 | |
| J | HIS186 | |
| J | HIS187 | |
| J | GLU190 | |
| A | HIS64 | |
| J | SER214 | |
| K | HIS64 | |
| K | HIS90 | |
| K | HIS91 | |
| K | GLU94 | |
| K | ARG116 | |
| K | HIS162 | |
| K | HIS186 | |
| K | HIS187 | |
| K | GLU190 | |
| A | HIS90 | |
| K | SER214 | |
| L | HIS64 | |
| L | HIS90 | |
| L | HIS91 | |
| L | GLU94 | |
| L | ARG116 | |
| L | HIS162 | |
| L | HIS186 | |
| L | HIS187 | |
| L | GLU190 | |
| A | HIS91 | |
| L | SER214 | |
| M | HIS64 | |
| M | HIS90 | |
| M | HIS91 | |
| M | GLU94 | |
| M | ARG116 | |
| M | HIS162 | |
| M | HIS186 | |
| M | HIS187 | |
| M | GLU190 | |
| A | GLU94 | |
| M | SER214 | |
| N | HIS64 | |
| N | HIS90 | |
| N | HIS91 | |
| N | GLU94 | |
| N | ARG116 | |
| N | HIS162 | |
| N | HIS186 | |
| N | HIS187 | |
| N | GLU190 | |
| A | ARG116 | |
| N | SER214 | |
| O | HIS64 | |
| O | HIS90 | |
| O | HIS91 | |
| O | GLU94 | |
| O | ARG116 | |
| O | HIS162 | |
| O | HIS186 | |
| O | HIS187 | |
| O | GLU190 | |
| A | HIS162 | |
| O | SER214 | |
| P | HIS64 | |
| P | HIS90 | |
| P | HIS91 | |
| P | GLU94 | |
| P | ARG116 | |
| P | HIS162 | |
| P | HIS186 | |
| P | HIS187 | |
| P | GLU190 | |
| A | HIS186 | |
| P | SER214 | |
| Q | HIS64 | |
| Q | HIS90 | |
| Q | HIS91 | |
| Q | GLU94 | |
| Q | ARG116 | |
| Q | HIS162 | |
| Q | HIS186 | |
| Q | HIS187 | |
| Q | GLU190 | |
| A | HIS187 | |
| Q | SER214 | |
| R | HIS64 | |
| R | HIS90 | |
| R | HIS91 | |
| R | GLU94 | |
| R | ARG116 | |
| R | HIS162 | |
| R | HIS186 | |
| R | HIS187 | |
| R | GLU190 | |
| A | GLU190 | |
| R | SER214 | |
| S | HIS64 | |
| S | HIS90 | |
| S | HIS91 | |
| S | GLU94 | |
| S | ARG116 | |
| S | HIS162 | |
| S | HIS186 | |
| S | HIS187 | |
| S | GLU190 | |
| U | HIS90 | |
| A | SER214 | |
| S | SER214 | |
| T | HIS64 | |
| T | HIS90 | |
| T | HIS91 | |
| T | GLU94 | |
| T | ARG116 | |
| T | HIS162 | |
| T | HIS186 | |
| T | HIS187 | |
| T | GLU190 | |
| B | HIS64 | |
| T | SER214 | |
| V | HIS64 | |
| V | HIS90 | |
| V | HIS91 | |
| V | GLU94 | |
| V | ARG116 | |
| V | HIS162 | |
| V | HIS186 | |
| V | HIS187 | |
| V | GLU190 | |
| B | HIS90 | |
| V | SER214 | |
| W | HIS64 | |
| W | HIS90 | |
| W | HIS91 | |
| W | GLU94 | |
| W | ARG116 | |
| W | HIS162 | |
| W | HIS186 | |
| W | HIS187 | |
| W | GLU190 | |
| B | HIS91 | |
| W | SER214 | |
| X | HIS64 | |
| X | HIS90 | |
| X | HIS91 | |
| X | GLU94 | |
| X | ARG116 | |
| X | HIS162 | |
| X | HIS186 | |
| X | HIS187 | |
| X | GLU190 | |
| B | GLU94 | |
| X | SER214 | |
| B | ARG116 | |
| B | HIS162 | |
| B | HIS186 | |
| B | HIS187 | |
| B | GLU190 | |
| U | HIS91 | |
| B | SER214 | |
| C | HIS64 | |
| C | HIS90 | |
| C | HIS91 | |
| C | GLU94 | |
| C | ARG116 | |
| C | HIS162 | |
| C | HIS186 | |
| C | HIS187 | |
| C | GLU190 | |
| U | GLU94 | |
| C | SER214 | |
| D | HIS64 | |
| D | HIS90 | |
| D | HIS91 | |
| D | GLU94 | |
| D | ARG116 | |
| D | HIS162 | |
| D | HIS186 | |
| D | HIS187 | |
| D | GLU190 | |
| U | ARG116 | |
| D | SER214 | |
| E | HIS64 | |
| E | HIS90 | |
| E | HIS91 | |
| E | GLU94 | |
| E | ARG116 | |
| E | HIS162 | |
| E | HIS186 | |
| E | HIS187 | |
| E | GLU190 | |
| U | HIS162 | |
| E | SER214 | |
| F | HIS64 | |
| F | HIS90 | |
| F | HIS91 | |
| F | GLU94 | |
| F | ARG116 | |
| F | HIS162 | |
| F | HIS186 | |
| F | HIS187 | |
| F | GLU190 | |
| U | HIS186 | |
| F | SER214 | |
| G | HIS64 | |
| G | HIS90 | |
| G | HIS91 | |
| G | GLU94 | |
| G | ARG116 | |
| G | HIS162 | |
| G | HIS186 | |
| G | HIS187 | |
| G | GLU190 | |
| U | HIS187 | |
| G | SER214 | |
| H | HIS64 | |
| H | HIS90 | |
| H | HIS91 | |
| H | GLU94 | |
| H | ARG116 | |
| H | HIS162 | |
| H | HIS186 | |
| H | HIS187 | |
| H | GLU190 | |
| U | GLU190 | |
| H | SER214 | |
| I | HIS64 | |
| I | HIS90 | |
| I | HIS91 | |
| I | GLU94 | |
| I | ARG116 | |
| I | HIS162 | |
| I | HIS186 | |
| I | HIS187 | |
| I | GLU190 |
