6EYK

E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV355

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CkCdpGfsGLkC

Chain	Residue	Details
A	CYS142-CYS153

---

site_id	PS00615
Number of Residues	28
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVeiyikrekdvgmWNDERCskkkl.ALC

Chain	Residue	Details
A	CYS90-CYS117

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CkCdpGFsglk....C

Chain	Residue	Details
A	CYS142-CYS153

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	117
Details	Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EGF-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	61
Details	Domain: {"description":"Sushi 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	61
Details	Domain: {"description":"Sushi 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26117840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4C16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26117840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ESL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11081633","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26117840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ESL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1G1T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11081633","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26117840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4C16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	7
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"26117840","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4C16","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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