6EXH

Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/succinate/(4R)-4-hydroxy-L-lysine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0055114	biological_process	obsolete oxidation-reduction process
B	0016491	molecular_function	oxidoreductase activity
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
B	0055114	biological_process	obsolete oxidation-reduction process
C	0016491	molecular_function	oxidoreductase activity
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0055114	biological_process	obsolete oxidation-reduction process
D	0016491	molecular_function	oxidoreductase activity
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity
D	0055114	biological_process	obsolete oxidation-reduction process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue FE A 401

Chain	Residue
A	HIS176
A	GLU178
A	HIS312
A	SIN403

---

site_id	AC2
Number of Residues	10
Details	binding site for residue LYO A 402

Chain	Residue
A	ASP230
A	ARG338
A	SIN403
A	HOH622
A	HOH639
A	TRP112
A	ARG145
A	GLY166
A	SER167
A	GLU178

---

site_id	AC3
Number of Residues	14
Details	binding site for residue SIN A 403

Chain	Residue
A	LEU173
A	HIS176
A	GLU178
A	PHE191
A	TYR193
A	HIS312
A	ARG314
A	ARG334
A	MET336
A	ARG338
A	FE401
A	LYO402
A	HOH513
A	HOH517

---

site_id	AC4
Number of Residues	2
Details	binding site for residue GOL A 404

Chain	Residue
A	THR354
A	ASP355

---

site_id	AC5
Number of Residues	4
Details	binding site for residue FE B 401

Chain	Residue
B	HIS176
B	GLU178
B	HIS312
B	SIN403

---

site_id	AC6
Number of Residues	12
Details	binding site for residue LYO B 402

Chain	Residue
B	GLN144
B	GLN164
B	GLY166
B	HIS176
B	GLU178
B	ASP260
B	ARG338
B	SIN403
B	HOH529
B	HOH537
B	HOH543
B	HOH562

---

site_id	AC7
Number of Residues	12
Details	binding site for residue SIN B 403

Chain	Residue
B	VAL154
B	GLY166
B	LEU173
B	HIS176
B	GLU178
B	HIS312
B	ARG314
B	ARG334
B	MET336
B	ARG338
B	FE401
B	LYO402

---

site_id	AC8
Number of Residues	4
Details	binding site for residue FE C 401

Chain	Residue
C	HIS176
C	GLU178
C	HIS312
C	HOH565

---

site_id	AC9
Number of Residues	10
Details	binding site for residue LYO C 402

Chain	Residue
C	GLN144
C	GLN164
C	THR165
C	GLY166
C	HIS176
C	GLU178
C	ASN232
C	GLU263
C	ARG338
C	HOH528

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL C 403

Chain	Residue
C	GLN102
C	ASP103
C	GLY106
C	PRO107
C	ARG195
C	GLU332

---

site_id	AD2
Number of Residues	5
Details	binding site for residue FE D 401

Chain	Residue
D	HIS176
D	GLU178
D	HIS312
D	SIN402
D	HOH572

---

site_id	AD3
Number of Residues	13
Details	binding site for residue SIN D 402

Chain	Residue
D	HIS176
D	GLU178
D	PHE191
D	TYR193
D	HIS312
D	GLY313
D	ARG334
D	MET336
D	ARG338
D	FE401
D	LYO404
D	HOH572
D	HOH590

---

site_id	AD4
Number of Residues	2
Details	binding site for residue GOL D 403

Chain	Residue
D	ALA48
D	HIS64

---

site_id	AD5
Number of Residues	12
Details	binding site for residue LYO D 404

Chain	Residue
D	GLN164
D	THR165
D	GLY166
D	HIS176
D	GLU178
D	ASP230
D	ASN232
D	ASP260
D	ARG338
D	SIN402
D	HOH530
D	GLN144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Z4Z5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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