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6EW9

CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0006508biological_processproteolysis
B0004252molecular_functionserine-type endopeptidase activity
B0006508biological_processproteolysis
C0004252molecular_functionserine-type endopeptidase activity
C0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue PEG A 401
ChainResidue
AALA267
APRO268
ALEU269

site_idAC2
Number of Residues2
Detailsbinding site for residue CA A 402
ChainResidue
AASP221
AHOH501

site_idAC3
Number of Residues4
Detailsbinding site for residue CA A 403
ChainResidue
AASN197
AHIS198
AGLY199
ASER201

site_idAC4
Number of Residues4
Detailsbinding site for residue CA A 404
ChainResidue
AHOH528
AHOH535
CCA401
CHOH517

site_idAC5
Number of Residues2
Detailsbinding site for residue CA A 405
ChainResidue
ATHR228
CASP221

site_idAC6
Number of Residues4
Detailsbinding site for residue CA B 401
ChainResidue
BASN197
BHIS198
BGLY199
BSER201

site_idAC7
Number of Residues3
Detailsbinding site for residue CA B 402
ChainResidue
BASP221
CTHR228
CHOH514

site_idAC8
Number of Residues5
Detailsbinding site for residue CA C 401
ChainResidue
ACA404
BHOH512
CASP193
CHOH517
CHOH521

site_idAC9
Number of Residues4
Detailsbinding site for residue CA C 402
ChainResidue
CASN197
CHIS198
CGLY199
CSER201

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsACT_SITE: Charge relay system => ECO:0000269|PubMed:15137941, ECO:0000269|PubMed:15225661, ECO:0000269|PubMed:20739286
ChainResidueDetails
AHIS96
AASP126
ASER201
BHIS96
BASP126
BSER201
CHIS96
CASP126
CSER201

site_idSWS_FT_FI2
Number of Residues9
DetailsBINDING:
ChainResidueDetails
ATHR184
AILE259
ATYR351
BTHR184
BILE259
BTYR351
CTHR184
CILE259
CTYR351

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PDB entries from 2024-11-06

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