6EW9
CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 401 |
| Chain | Residue |
| A | ALA267 |
| A | PRO268 |
| A | LEU269 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | ASP221 |
| A | HOH501 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASN197 |
| A | HIS198 |
| A | GLY199 |
| A | SER201 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | HOH528 |
| A | HOH535 |
| C | CA401 |
| C | HOH517 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 405 |
| Chain | Residue |
| A | THR228 |
| C | ASP221 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| B | ASN197 |
| B | HIS198 |
| B | GLY199 |
| B | SER201 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | ASP221 |
| C | THR228 |
| C | HOH514 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 401 |
| Chain | Residue |
| A | CA404 |
| B | HOH512 |
| C | ASP193 |
| C | HOH517 |
| C | HOH521 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 402 |
| Chain | Residue |
| C | ASN197 |
| C | HIS198 |
| C | GLY199 |
| C | SER201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 135 |
| Details | Domain: {"description":"PDZ","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15137941","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15225661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20739286","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Binding site: {} |
| Chain | Residue | Details |
