6EVQ

solution NMR structure of EB1 C terminus (191-260) with a small molecule bound into the SxIP binding site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008017	molecular_function	microtubule binding
B	0008017	molecular_function	microtubule binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue C05 A 301

Chain	Residue
A	GLU225
A	LEU246
A	TYR247
A	THR249
B	TYR217

---

site_id	AC2
Number of Residues	5
Details	binding site for residue C05 B 301

Chain	Residue
B	THR249
A	TYR217
B	GLU225
B	LEU246
B	TYR247

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Region: {"description":"Interaction with APC","evidences":[{"source":"PubMed","id":"15311282","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	44
Details	Region: {"description":"APC-binding","evidences":[{"source":"UniProtKB","id":"Q15691","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	46
Details	Region: {"description":"Interaction with SKA1","evidences":[{"source":"UniProtKB","id":"Q15691","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q15691","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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