6EUY

Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication
B	0003723	molecular_function	RNA binding
B	0039694	biological_process	viral RNA genome replication
C	0003723	molecular_function	RNA binding
C	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue BYB A 601

Chain	Residue
A	PHE323
A	GLN406
A	MET431
A	ASN510
A	VAL511
A	LEU512
A	ARG332
A	SER337
A	ARG355
A	HIS357
A	GLU361
A	PHE363
A	LYS376
A	PHE404

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site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 602

Chain	Residue
A	SER273
A	ALA274
B	ARG299

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 603

Chain	Residue
A	LEU317
A	ARG318
A	ARG493
C	ARG500

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 604

Chain	Residue
A	ARG264
A	LYS368
A	HIS522

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site_id	AC5
Number of Residues	1
Details	binding site for residue SO4 A 605

Chain	Residue
A	LYS482

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site_id	AC6
Number of Residues	14
Details	binding site for residue BYB B 601

Chain	Residue
B	PHE323
B	PHE325
B	ARG332
B	ARG355
B	HIS357
B	GLU361
B	PHE363
B	LYS376
B	PHE404
B	GLN406
B	MET431
B	ASN510
B	VAL511
B	LEU512

---

site_id	AC7
Number of Residues	14
Details	binding site for residue BYB C 601

Chain	Residue
C	PHE323
C	PHE325
C	ARG332
C	SER337
C	HIS357
C	GLU361
C	PHE363
C	LYS376
C	PHE404
C	GLN406
C	MET431
C	ASN510
C	VAL511
C	LEU512

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 C 602

Chain	Residue
A	GLU341
C	LYS339
C	ARG508

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site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 C 603

Chain	Residue
A	ARG500
C	LEU317
C	ARG318

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