6EUW

Crystal structure of the cap-binding domain of the PB2 subunit of influenza A/H5N1 polymerase bound to an azaindazole inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue BYB A 501

Chain	Residue
A	ILE319
A	PHE363
A	LYS376
A	PHE404
A	GLN406
A	ASN425
A	MET427
A	HOH611
A	HOH645
A	HOH671
A	HOH681
A	SER320
A	PHE323
A	SER324
A	ARG332
A	SER337
A	ARG355
A	HIS357
A	GLU361

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 502

Chain	Residue
A	GLY327
A	GLY367
A	ARG368
A	ARG369
A	ALA370
A	GLU396
A	HOH619

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site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 503

Chain	Residue
A	GLN392
A	ILE399
A	GLN435
A	LYS436
A	ASP437
A	ALA438
A	HOH601
A	HOH657

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