6EUR

Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/alpha-ketoglutarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0055114	biological_process	obsolete oxidation-reduction process
B	0016491	molecular_function	oxidoreductase activity
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
B	0055114	biological_process	obsolete oxidation-reduction process
C	0016491	molecular_function	oxidoreductase activity
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
C	0055114	biological_process	obsolete oxidation-reduction process
D	0016491	molecular_function	oxidoreductase activity
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity
D	0055114	biological_process	obsolete oxidation-reduction process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue FE A 401

Chain	Residue
A	HIS176
A	GLU178
A	HIS312
A	AKG402

---

site_id	AC2
Number of Residues	13
Details	binding site for residue AKG A 402

Chain	Residue
A	HIS312
A	ARG314
A	ARG334
A	MET336
A	ARG338
A	FE401
A	HOH543
A	HOH555
A	LEU173
A	HIS176
A	GLU178
A	PHE191
A	TYR193

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 403

Chain	Residue
A	ARG353
A	THR354
A	ASP355
A	MET361
A	HOH589

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 404

Chain	Residue
A	GLU53
A	GLN140
A	ASP356
A	TYR358

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 405

Chain	Residue
A	GLU53
A	GLY148
A	GLY149
A	HOH644
D	LYS159

---

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL A 406

Chain	Residue
A	ALA245
A	SER246
A	TYR249
A	ARG258

---

site_id	AC7
Number of Residues	5
Details	binding site for residue FE B 401

Chain	Residue
B	HIS176
B	GLU178
B	HIS312
B	AKG402
B	HOH620

---

site_id	AC8
Number of Residues	12
Details	binding site for residue AKG B 402

Chain	Residue
B	VAL154
B	HIS176
B	GLU178
B	PHE191
B	TYR193
B	HIS312
B	GLY313
B	ARG334
B	MET336
B	ARG338
B	FE401
B	HOH590

---

site_id	AC9
Number of Residues	3
Details	binding site for residue GOL B 403

Chain	Residue
B	GLN33
D	LEU44
D	LEU45

---

site_id	AD1
Number of Residues	5
Details	binding site for residue FE C 401

Chain	Residue
C	HIS176
C	GLU178
C	HIS312
C	AKG402
C	HOH595

---

site_id	AD2
Number of Residues	14
Details	binding site for residue AKG C 402

Chain	Residue
C	VAL154
C	LEU173
C	HIS176
C	GLU178
C	PHE191
C	TYR193
C	HIS312
C	GLY313
C	ARG314
C	ARG334
C	ARG338
C	FE401
C	HOH528
C	HOH556

---

site_id	AD3
Number of Residues	5
Details	binding site for residue GOL C 403

Chain	Residue
C	GLU53
C	GLN140
C	ASP356
C	TYR358
C	HOH535

---

site_id	AD4
Number of Residues	6
Details	binding site for residue GOL C 404

Chain	Residue
C	GLN102
C	ASP103
C	GLY106
C	PRO107
C	ARG195
C	GLU332

---

site_id	AD5
Number of Residues	4
Details	binding site for residue GOL C 405

Chain	Residue
C	THR352
C	THR354
C	MET361
C	ILE368

---

site_id	AD6
Number of Residues	4
Details	binding site for residue FE D 401

Chain	Residue
D	HIS176
D	GLU178
D	HIS312
D	AKG402

---

site_id	AD7
Number of Residues	11
Details	binding site for residue AKG D 402

Chain	Residue
D	ARG314
D	ARG334
D	MET336
D	ARG338
D	FE401
D	LEU173
D	HIS176
D	GLU178
D	PHE191
D	TYR193
D	HIS312

---

site_id	AD8
Number of Residues	6
Details	binding site for residue GOL D 403

Chain	Residue
D	ASP172
D	PHE174
D	VAL175
D	ILE291
D	HOH550
D	HOH561

---

site_id	AD9
Number of Residues	3
Details	binding site for residue GOL D 404

Chain	Residue
D	TRP112
D	ARG145
D	SER167

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Z4Z5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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