6ERA
Crystal structure of cyclohexanone monooxygenase mutant (F249A, F280A and F435A) from Rhodococcus sp. Phi1 bound to NADP+
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
A | 0050661 | molecular_function | NADP binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 26 |
Details | binding site for residue FAD A 601 |
Chain | Residue |
A | GLY16 |
A | TRP51 |
A | TYR54 |
A | LEU58 |
A | SER59 |
A | ASP60 |
A | THR61 |
A | TYR66 |
A | GLU112 |
A | VAL113 |
A | ALA143 |
A | GLY18 |
A | VAL144 |
A | GLY145 |
A | ASN437 |
A | LEU438 |
A | NAP602 |
A | HOH702 |
A | HOH721 |
A | PHE19 |
A | GLY20 |
A | ASP40 |
A | LYS41 |
A | GLY47 |
A | THR48 |
A | TRP49 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue NAP A 602 |
Chain | Residue |
A | PRO153 |
A | ILE185 |
A | GLY186 |
A | THR187 |
A | GLY188 |
A | THR190 |
A | ARG210 |
A | THR211 |
A | ARG330 |
A | ALA380 |
A | THR381 |
A | GLY382 |
A | ASN437 |
A | FAD601 |
site_id | AC3 |
Number of Residues | 25 |
Details | binding site for residue FAD B 601 |
Chain | Residue |
B | ILE15 |
B | GLY16 |
B | GLY18 |
B | PHE19 |
B | GLY20 |
B | ASP40 |
B | LYS41 |
B | GLY47 |
B | THR48 |
B | TRP49 |
B | TRP51 |
B | TYR54 |
B | SER59 |
B | ASP60 |
B | THR61 |
B | TYR66 |
B | VAL113 |
B | ALA143 |
B | VAL144 |
B | GLY145 |
B | ASN389 |
B | ASN437 |
B | LEU438 |
B | NAP602 |
B | HOH702 |
site_id | AC4 |
Number of Residues | 14 |
Details | binding site for residue NAP B 602 |
Chain | Residue |
B | ASP60 |
B | PRO153 |
B | ILE185 |
B | GLY186 |
B | THR187 |
B | GLY188 |
B | SER189 |
B | THR190 |
B | ARG210 |
B | THR211 |
B | ALA380 |
B | THR381 |
B | GLY382 |
B | FAD601 |