6EQL
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue UDP A 301 |
| Chain | Residue |
| A | LEU9 |
| A | HIS212 |
| A | LEU214 |
| A | GLY215 |
| A | LYS218 |
| A | MN302 |
| A | THR10 |
| A | THR11 |
| A | ASN12 |
| A | TYR15 |
| A | ARG30 |
| A | ASP102 |
| A | ALA103 |
| A | ASP104 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MN A 302 |
| Chain | Residue |
| A | ASP102 |
| A | ASP104 |
| A | HIS212 |
| A | UDP301 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue UDP B 301 |
| Chain | Residue |
| B | LEU9 |
| B | THR10 |
| B | THR11 |
| B | ASN12 |
| B | TYR15 |
| B | VAL82 |
| B | ASP102 |
| B | ALA103 |
| B | ASP104 |
| B | HIS212 |
| B | LEU214 |
| B | GLY215 |
| B | LYS218 |
| B | MN302 |
| B | 2PE303 |
| B | EDO304 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 302 |
| Chain | Residue |
| B | ASP102 |
| B | ASP104 |
| B | HIS212 |
| B | UDP301 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue 2PE B 303 |
| Chain | Residue |
| B | ASP125 |
| B | ASN133 |
| B | SER134 |
| B | GLY162 |
| B | ASP163 |
| B | GLN164 |
| B | GLY215 |
| B | UDP301 |
| B | EDO304 |
| B | HOH413 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | UDP301 |
| B | 2PE303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22160680, ECO:0000269|PubMed:30356213, ECO:0007744|PDB:3RMW, ECO:0007744|PDB:3T7O |
| Chain | Residue | Details |
| A | LEU9 | |
| B | LEU9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22160680, ECO:0007744|PDB:3T7M, ECO:0007744|PDB:3T7N, ECO:0007744|PDB:3T7O, ECO:0007744|PDB:3U2U, ECO:0007744|PDB:3U2V, ECO:0007744|PDB:3U2W, ECO:0007744|PDB:3U2X |
| Chain | Residue | Details |
| A | ARG77 | |
| B | ARG77 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22160680, ECO:0000269|PubMed:30356213, ECO:0007744|PDB:3QVB, ECO:0007744|PDB:3RMV, ECO:0007744|PDB:3RMW, ECO:0007744|PDB:3T7M, ECO:0007744|PDB:3T7N, ECO:0007744|PDB:3T7O, ECO:0007744|PDB:3U2T, ECO:0007744|PDB:3U2U, ECO:0007744|PDB:3U2V, ECO:0007744|PDB:3U2W, ECO:0007744|PDB:3U2X |
| Chain | Residue | Details |
| A | ASP102 | |
| A | ASP104 | |
| A | HIS212 | |
| B | ASP102 | |
| B | ASP104 | |
| B | HIS212 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22160680, ECO:0007744|PDB:3RMW, ECO:0007744|PDB:3T7O |
| Chain | Residue | Details |
| A | ASN133 | |
| A | ASP160 | |
| B | ASN133 | |
| B | ASP160 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Important for catalytic activity => ECO:0000250|UniProtKB:P13280 |
| Chain | Residue | Details |
| A | LYS86 | |
| B | LYS86 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 |
| Chain | Residue | Details |
| A | THR2 | |
| B | THR2 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P13280 |
| Chain | Residue | Details |
| A | SER44 | |
| B | SER44 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: O-linked (Glc...) tyrosine => ECO:0000269|PubMed:22160680, ECO:0000269|PubMed:30356213, ECO:0007744|PDB:3U2U, ECO:0007744|PDB:3U2V |
| Chain | Residue | Details |
| A | PHI195 | |
| B | PHI195 |
