6EOP
DPP8 - SLRFLYEG, space group 20
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004177 | molecular_function | aminopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006508 | biological_process | proteolysis |
A | 0006915 | biological_process | apoptotic process |
A | 0006955 | biological_process | immune response |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
A | 0043069 | biological_process | negative regulation of programmed cell death |
B | 0004177 | molecular_function | aminopeptidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006508 | biological_process | proteolysis |
B | 0006915 | biological_process | apoptotic process |
B | 0006955 | biological_process | immune response |
B | 0008236 | molecular_function | serine-type peptidase activity |
B | 0008239 | molecular_function | dipeptidyl-peptidase activity |
B | 0043069 | biological_process | negative regulation of programmed cell death |
C | 0004177 | molecular_function | aminopeptidase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0006508 | biological_process | proteolysis |
C | 0006915 | biological_process | apoptotic process |
C | 0006955 | biological_process | immune response |
C | 0008236 | molecular_function | serine-type peptidase activity |
C | 0008239 | molecular_function | dipeptidyl-peptidase activity |
C | 0043069 | biological_process | negative regulation of programmed cell death |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue FLC A 901 |
Chain | Residue |
A | HIS172 |
A | PRO222 |
A | ALA223 |
A | PRO287 |
A | LYS288 |
A | ALA289 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue CA A 902 |
Chain | Residue |
A | TYR280 |
A | HOH1019 |
A | ARG158 |
A | GLN274 |
A | ASP278 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue CA B 901 |
Chain | Residue |
B | ARG158 |
B | GLN274 |
B | GLU275 |
B | ASP278 |
B | TYR280 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue CA C 901 |
Chain | Residue |
C | ARG158 |
C | GLN274 |
C | ASP278 |
C | TYR280 |
C | HOH1042 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue F15 D 101 |
Chain | Residue |
A | PHE667 |
A | TYR669 |
A | VAL674 |
A | TYR686 |
A | ARG688 |
A | TYR876 |
D | ARG12 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue F15 E 101 |
Chain | Residue |
B | TYR669 |
B | TYR686 |
B | ARG688 |
B | TYR876 |
E | ARG12 |
E | PHE13 |
E | HOH201 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue F15 F 101 |
Chain | Residue |
C | TYR686 |
C | ARG688 |
C | TYR876 |
C | LEU880 |
F | ARG12 |
F | PHE13 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 9 |
Details | ACT_SITE: Charge relay system => ECO:0000305|PubMed:12534281, ECO:0000305|PubMed:29382749 |
Chain | Residue | Details |
A | SER755 | |
A | ASP833 | |
A | HIS865 | |
B | SER755 | |
B | ASP833 | |
B | HIS865 | |
C | SER755 | |
C | ASP833 | |
C | HIS865 |